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  Domain Name: Pep_M12B_propep
Reprolysin family propeptide. This region is the propeptide for members of peptidase family M12B. The propeptide contains a sequence motif similar to the "cysteine switch" of the matrixins. This motif is found at the C terminus of the alignment but is not well aligned.
No pairwise interactions found for the domain Pep_M12B_propep

Total Mutations Found: 84
Total Disease Mutations Found: 4
This domain occurred 37 times on human genes (71 proteins).



  MICROCORNEA, MYOPIC CHORIORETINAL ATROPHY, AND TELECANTHUS
  RECLASSIFIED - VARIANT OF UNKNOWN SIGNIFICANCE
  RETICULATE ACROPIGMENTATION OF KITAMURA
  WEILL-MARCHESANI SYNDROME 1


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Pep_M12B_propep













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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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