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  Domain Name: RabGAP-TBC
Rab-GTPase-TBC domain. Identification of a TBC domain in GYP6_YEAST and GYP7_YEAST, which are GTPase activator proteins of yeast Ypt6 and Ypt7, implies that these domains are GTPase activator proteins of Rab-like small GTPases.
No pairwise interactions found for the domain RabGAP-TBC

Total Mutations Found: 19
Total Disease Mutations Found: 5
This domain occurred 42 times on human genes (65 proteins).



  DEAFNESS, ONYCHODYSTROPHY, OSTEODYSTROPHY, MENTAL RETARDATION, AND
  EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 16
  MYOCLONIC EPILEPSY, INFANTILE, FAMILIAL
  SEIZURES SYNDROME


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for RabGAP-TBC
















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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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