Results for the gene: EPHA2

Results for Proteins associated with the Gene: EPHA2

EPHA2

1969

P29317 NP_004422

NCBI

Known Diseases associated with this Protein:

CATARACT 6, AGE-RELATED CORTICAL

CATARACT 6, MULTIPLE TYPES (CTRCT6)

CATARACT 6, POSTERIOR POLAR

			6 8 3 2 9

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

Clicking a check box on the left will display or hide the corresponding domain(s).

To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: P29317

Identical to: NP_004422

Default View:

RefSeq Protein: NP_004422

Default View:

Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_004422	FN3	cd00063	437	526	6.7e-17
NP_004422	PTKc_VEGFR	cd05054	468	878	8.2e-22
NP_004422	PTKc_Kit	cd05104	573	875	1.2e-13
NP_004422	PTKc_PDGFR_alpha	cd05105	575	877	3.9e-13
NP_004422	PTKc_PDGFR_beta	cd05107	575	876	1.1e-09
NP_004422	STKc_PAK1	cd06654	577	885	0.00012
NP_004422	STKc_PAK_I	cd06647	578	894	9e-05
NP_004422	STKc_PAK5	cd06658	578	889	8.7e-05
NP_004422	PTKc_PDGFR	cd05055	581	875	2e-17
NP_004422	PTKc_CSF-1R	cd05106	583	876	7.2e-19
NP_004422	STKc_TAO1	cd06635	591	898	0.00019
NP_004422	PTKc_FGFR1	cd05098	592	882	1.9e-38
NP_004422	STKc_MAP4K4_6	cd06636	592	867	0.00019
NP_004422	STKc_myosinIIIB	cd06639	592	876	0.00018
NP_004422	PTKc_FGFR2	cd05101	593	886	2.8e-44
NP_004422	STKc_TAO3	cd06633	593	898	0.00034
NP_004422	STKc_PAK4	cd06657	593	892	0.00016
NP_004422	STKc_PAK6	cd06659	593	895	1e-06
NP_004422	STKc_JNK	cd07850	593	920	0.00052
NP_004422	PTKc_EGFR_like	cd05057	594	885	3.3e-78
NP_004422	STKc_PAK	cd06614	594	888	1.5e-12
NP_004422	STKc_myosinIIIA	cd06638	594	875	0.00013
NP_004422	STKc_PAK_II	cd06648	595	885	2.2e-08
NP_004422	STKc_TAO	cd06607	596	898	2.2e-05
NP_004422	STKc_TAO2	cd06634	596	899	8.1e-06
NP_004422	STKc_PAK2	cd06655	597	885	0.00045
NP_004422	STKc_JNK2	cd07876	597	946	0.00073
NP_004422	STKc_PAK3	cd06656	598	886	6.9e-05
NP_004422	STKc_p38	cd07851	598	923	9.1e-06
NP_004422	STKc_p38gamma_MAPK12	cd07880	598	949	1.2e-05
NP_004422	STKc_CDK9	cd07865	598	906	1.4e-06
NP_004422	PTK_Tyk2_rpt1	cd05076	600	872	1.2e-08
NP_004422	PTKc_FGFR3	cd05100	600	920	3.2e-32
NP_004422	STKc_MAP4K5	cd06646	600	872	0.00036
NP_004422	STKc_PCTAIRE2	cd07872	600	922	7.8e-05
NP_004422	PKc_MKK7	cd06618	601	894	1.3e-07
NP_004422	STKc_Sty1_Hog1	cd07856	601	942	3.4e-06
NP_004422	PTKc_FGFR4	cd05099	602	890	2.4e-46
NP_004422	PTKc_EGFR	cd05108	602	924	2.6e-54
NP_004422	PTKc_HER4	cd05110	602	912	5.2e-56
NP_004422	STKc_STK10_LOK	cd06644	603	891	9e-06
NP_004422	STKc_MAP4K3	cd06645	603	879	0.0001
NP_004422	STKc_ASK	cd06624	604	875	4.9e-12
NP_004422	STKc_SLK	cd06643	604	880	6.7e-06
NP_004422	STKc_ERK5	cd07855	604	911	0.00077
NP_004422	PTKc_VEGFR3	cd05102	605	878	1.1e-24
NP_004422	PTKc_VEGFR2	cd05103	605	878	2.3e-21
NP_004422	PTK_HER3	cd05111	605	885	3.8e-49
NP_004422	PTKc_ALK_LTK	cd05036	606	873	9.1e-74
NP_004422	PTKc_FAK	cd05056	606	879	2.4e-90
NP_004422	PTKc_Tie2	cd05088	606	895	8.9e-42
NP_004422	STKc_ERK1_2_like	cd07849	606	935	4.5e-06
NP_004422	STKc_TEY_MAPK_plant	cd07858	606	962	1.3e-06
NP_004422	PTKc_InsR_like	cd05032	607	873	5.9e-77
NP_004422	PTKc_Csk_like	cd05039	607	877	3.9e-67
NP_004422	PTK_CCK4	cd05046	607	873	2.4e-42
NP_004422	PTKc_Ror	cd05048	607	874	9.3e-65
NP_004422	PTKc_Musk	cd05050	607	873	1e-68
NP_004422	PTKc_DDR	cd05051	607	873	2e-53
NP_004422	PTKc_Abl	cd05052	607	875	7.2e-84
NP_004422	PTKc_Trk	cd05049	607	873	1.9e-76
NP_004422	PTKc_InsR	cd05061	607	886	2.6e-60
NP_004422	PTKc_IGF-1R	cd05062	607	873	3.5e-58
NP_004422	PTKc_EphR_A2	cd05063	607	875	2.8e-232
NP_004422	PTKc_EphR_A10	cd05064	607	875	4e-135
NP_004422	PTKc_Lck_Blk	cd05067	607	874	3.7e-76
NP_004422	PTKc_Frk_like	cd05068	607	874	4.6e-97
NP_004422	PTKc_Yes	cd05069	607	874	4.6e-73
NP_004422	PTKc_Fyn_Yrk	cd05070	607	874	3e-77
NP_004422	PTKc_Src	cd05071	607	876	4.8e-73
NP_004422	PTKc_Src_like	cd05034	607	874	8.6e-101
NP_004422	PTKc_Hck	cd05073	607	874	9.9e-78
NP_004422	PTKc_Lyn	cd05072	607	874	4.2e-80
NP_004422	PTKc_Ror1	cd05090	607	874	2.8e-58
NP_004422	PTKc_Ror2	cd05091	607	874	5.5e-54
NP_004422	PTKc_DDR2	cd05095	607	873	6.7e-54
NP_004422	PTKc_DDR1	cd05096	607	873	5e-44
NP_004422	PTKc_DDR_like	cd05097	607	873	4.3e-56
NP_004422	PTKc_TrkB	cd05093	607	882	9.5e-59
NP_004422	PTKc_Csk	cd05082	607	874	6.3e-61
NP_004422	PTKc_FGFR	cd05053	607	876	1.5e-44
NP_004422	PTKc_TrkC	cd05094	607	882	1.4e-39
NP_004422	STKc_TNIK	cd06637	607	875	3.5e-05
NP_004422	PKc_MAPKK_Byr1_like	cd06620	607	922	4.3e-06
NP_004422	PTKc_EphR	cd05033	608	875	2.4e-224
NP_004422	PTK_Ryk	cd05043	608	874	1.6e-26
NP_004422	PTKc_Jak_rpt2	cd05038	608	875	6e-69
NP_004422	PTKc_Tec_like	cd05059	608	872	1.3e-81
NP_004422	PTKc_EphR_B	cd05065	608	875	8.7e-179
NP_004422	PTKc_Jak1_rpt2	cd05079	608	875	5.2e-44
NP_004422	PTKc_Tyk2_rpt2	cd05080	608	876	7.1e-26
NP_004422	PTKc_EphR_A	cd05066	608	875	2.3e-190
NP_004422	PTKc_Chk	cd05083	608	874	3.4e-68
NP_004422	PTKc_HER2	cd05109	608	885	4.9e-60
NP_004422	PTKc_Itk	cd05112	608	872	1.5e-82
NP_004422	PTKc_Btk_Bmx	cd05113	608	872	1e-77
NP_004422	PTKc_Tec_Rlk	cd05114	608	872	3e-83
NP_004422	STKc_MAPK15	cd07852	608	919	8.4e-05
NP_004422	STKc_PCTAIRE_like	cd07844	609	906	1.3e-07
NP_004422	STKc_CDK12	cd07864	609	884	2.1e-09
NP_004422	STKc_PFTAIRE2	cd07870	609	907	9.1e-06
NP_004422	STKc_MST1_2	cd06612	610	846	5.8e-11
NP_004422	STKc_MEKK3_like	cd06625	610	873	1.7e-10
NP_004422	STKc_MEKK3	cd06651	610	867	2.7e-08
NP_004422	STKc_MEKK2	cd06652	610	876	6.6e-05
NP_004422	STKc_MEKK3_like_1	cd06653	610	880	7e-07
NP_004422	STKc_CDK10	cd07845	610	896	6e-07
NP_004422	STKc_Nek4	cd08223	610	876	1.1e-06
NP_004422	STKc_PKA	cd05580	611	895	1.1e-06
NP_004422	STKc_MAST	cd05609	611	926	8.1e-05
NP_004422	STKc_PRKX_like	cd05612	611	896	3.1e-06
NP_004422	PKc_MAPKK	cd06605	611	869	2.7e-09
NP_004422	STKc_MST3_like	cd06609	611	882	1.5e-11
NP_004422	PKc_MEK	cd06615	611	917	3.2e-07
NP_004422	PKc_MKK3_6	cd06617	611	886	1.1e-06
NP_004422	PKc_MKK5	cd06619	611	917	4.4e-05
NP_004422	PKc_MAPKK_Pek1_like	cd06621	611	888	5.7e-07
NP_004422	STKc_MST4	cd06640	611	892	2.9e-08
NP_004422	STKc_MST3	cd06641	611	882	1.8e-07
NP_004422	STKc_STK25-YSK1	cd06642	611	892	8.2e-09
NP_004422	PKc_MAPKK_plant_like	cd06623	611	880	6.2e-12
NP_004422	PKc_MAPKK_PBS2_like	cd06622	611	920	1e-07
NP_004422	STKc_NAK1_like	cd06917	611	879	1.2e-08
NP_004422	STKc_CDK6	cd07862	611	907	0.00066
NP_004422	STKc_PCTAIRE3	cd07871	611	906	6e-06
NP_004422	STKc_PCTAIRE1	cd07873	611	918	4.2e-05
NP_004422	STKc_CDKL1_4	cd07847	611	906	9e-07
NP_004422	STKc_Nek7	cd08229	611	876	3e-07
NP_004422	STKc_Nek6	cd08228	611	876	3e-05
NP_004422	SPS1	COG0515	611	974	8.3e-25
NP_004422	PTKc_RET	cd05045	612	878	8.5e-51
NP_004422	PTKc_TrkA	cd05092	612	873	2.3e-61
NP_004422	PKc_STE	cd05122	612	864	1.9e-15
NP_004422	STKc_GRK4_like	cd05605	612	910	0.00016
NP_004422	STKc_MSK1_N	cd05613	612	889	0.00039
NP_004422	STKc_cPKC_alpha	cd05615	612	932	0.00057
NP_004422	STKc_MAPKKK	cd06606	612	865	4.2e-19
NP_004422	STKc_MAPKKK_Byr2_lik	cd06628	612	873	6.7e-17
NP_004422	STKc_Pho85	cd07836	612	906	1.6e-07
NP_004422	STKc_NLK	cd07853	612	963	5.4e-07
NP_004422	STKc_TDY_MAPK_plant	cd07859	612	955	3e-07
NP_004422	STKc_CDK9_like	cd07840	612	884	2.6e-10
NP_004422	PTKc_Axl_like	cd05035	613	875	4.5e-60
NP_004422	PTKc_Axl	cd05075	613	875	4.1e-49
NP_004422	PTKc_Tyro3	cd05074	613	875	1.3e-53
NP_004422	PTKc_Tie1	cd05089	613	896	6.1e-47
NP_004422	STKc_cPKC	cd05587	613	948	3.3e-05
NP_004422	STKc_PKN	cd05589	613	922	7.4e-06
NP_004422	STKc_MSK2_N	cd05614	613	935	0.00052
NP_004422	STKc_CDK1_like	cd07835	613	904	1.7e-06
NP_004422	STKc_MAPK	cd07834	613	928	5.4e-07
NP_004422	STKc_CDK1_euk	cd07861	613	907	5.5e-05
NP_004422	STKc_Nek1	cd08218	613	876	3.8e-09
NP_004422	STKc_CMGC	cd05118	614	864	6.1e-10
NP_004422	PTKc_Srm_Brk	cd05148	614	874	9.1e-81
NP_004422	STKc_MEKK1	cd06630	614	865	1.6e-06
NP_004422	STKc_YSK4	cd06631	614	871	1.6e-08
NP_004422	STKc_CDK_like	cd07829	614	882	6.5e-11
NP_004422	STKc_MAK_like	cd07830	614	864	8.2e-09
NP_004422	STKc_CdkB_plant	cd07837	614	901	2.8e-06
NP_004422	STKc_CDK5	cd07839	614	906	2.2e-06
NP_004422	STKc_CDK7	cd07841	614	896	4.9e-09
NP_004422	STKc_CDK2_3	cd07860	614	904	8.4e-06
NP_004422	STKc_Nek	cd08215	614	876	4.1e-16
NP_004422	STKc_Nek8	cd08220	614	875	1.5e-07
NP_004422	STKc_Nek9	cd08221	614	876	3e-08
NP_004422	STKc_MEKK4	cd06626	615	865	5.9e-10
NP_004422	STKc_Yank1	cd05578	616	870	3.7e-06
NP_004422	STKc_RSK_N	cd05582	616	922	2.2e-06
NP_004422	STKc_p70S6K	cd05584	616	933	1.7e-05
NP_004422	STKc_CRIK	cd05601	616	933	0.00034
NP_004422	STKc_OSR1_SPAK	cd06610	616	865	2.4e-10
NP_004422	STKc_MAP4K3_like	cd06613	616	872	2.7e-10
NP_004422	STKc_Cdc7_like	cd06627	616	864	2e-16
NP_004422	STKc_CDKL	cd07833	616	864	0.00016
NP_004422	STKc_Nek11	cd08222	616	875	1.1e-11
NP_004422	STKc_Nek6_Nek7	cd08224	616	876	6.7e-08
NP_004422	STKc_CNK2-like	cd08530	616	871	8.5e-08
NP_004422	PTKc	cd00192	617	872	1.5e-139
NP_004422	PTKc_Ack_like	cd05040	617	873	2.3e-79
NP_004422	PTKc_Fes_like	cd05041	617	873	5.4e-86
NP_004422	PTKc_Aatyk	cd05042	617	873	7.6e-16
NP_004422	PTK_Jak_rpt1	cd05037	617	872	2.4e-12
NP_004422	PTKc_c-ros	cd05044	617	873	8.5e-72
NP_004422	PTKc_Tie	cd05047	617	876	5e-53
NP_004422	PTKc_Syk_like	cd05060	617	876	3.3e-88
NP_004422	PTKc_Met_Ron	cd05058	617	877	4.4e-69
NP_004422	PTK_Jak1_rpt1	cd05077	617	872	2.8e-11
NP_004422	PTK_Jak2_Jak3_rpt1	cd05078	617	872	7.7e-13
NP_004422	PTKc_Jak2_Jak3_rpt2	cd05081	617	875	2.9e-43
NP_004422	PTKc_Fes	cd05084	617	873	2e-73
NP_004422	PTKc_Fer	cd05085	617	873	4.1e-76
NP_004422	PTKc_Aatyk2	cd05086	617	873	4.8e-21
NP_004422	PTKc_Aatyk1_Aatyk3	cd05087	617	873	1.5e-23
NP_004422	PTKc_Syk	cd05116	617	876	1.4e-65
NP_004422	STKc_PKC	cd05570	617	909	6.6e-06
NP_004422	STKc_PKB	cd05571	617	924	2.5e-06
NP_004422	STKc_phototropin_lik	cd05574	617	883	2.6e-05
NP_004422	STKc_SGK	cd05575	617	931	0.0001
NP_004422	STKc_PDK1	cd05581	617	887	1.7e-08
NP_004422	STKc_MSK_N	cd05583	617	889	0.00058
NP_004422	STKc_nPKC_theta_delt	cd05592	617	929	0.00015
NP_004422	STKc_PKB_gamma	cd05593	617	936	0.00029
NP_004422	STKc_PKB_alpha	cd05594	617	915	0.00011
NP_004422	STKc_PKB_beta	cd05595	617	933	0.00047
NP_004422	STKc_nPKC_epsilon	cd05591	617	964	4.4e-05
NP_004422	STKc_SGK1	cd05602	617	933	4.9e-05
NP_004422	STKc_SGK2	cd05603	617	932	2.3e-05
NP_004422	STKc_nPKC_theta	cd05619	617	928	0.00013
NP_004422	STKc_myosinIII_like	cd06608	617	870	7.3e-09
NP_004422	STKc_MEKK1_plant	cd06632	617	868	3e-10
NP_004422	STKc_MAPKKK_Bck1_lik	cd06629	617	865	2e-11
NP_004422	STKc_MAPK4_6	cd07854	617	931	3.7e-05
NP_004422	STKc_MPK1	cd07857	617	926	5.1e-07
NP_004422	STKc_Nek2	cd08217	617	875	6.3e-07
NP_004422	STKc_Nek3	cd08219	617	871	3.1e-09
NP_004422	STKc_Nek5	cd08225	617	876	5.4e-09
NP_004422	STKc_Nek10	cd08528	617	873	5.4e-06
NP_004422	STKc_FA2-like	cd08529	617	881	9.9e-09
NP_004422	STKc_beta_ARK	cd05606	618	884	0.00024
NP_004422	STKc_CCRK	cd07832	618	865	1.9e-06
NP_004422	STKc_CDKL2_3	cd07846	618	869	3.4e-06
NP_004422	STKc_BUR1	cd07866	618	882	1.1e-06
NP_004422	PKc	cd00180	619	871	2e-63
NP_004422	STKc_AGC	cd05123	619	866	8e-08
NP_004422	PTKc_Zap-70	cd05115	619	876	3.3e-75
NP_004422	STKc_cGK_PKG	cd05572	619	874	2e-06
NP_004422	STKc_GRK	cd05577	619	879	0.00074
NP_004422	STKc_MAST_like	cd05579	619	869	4.9e-06
NP_004422	STKc_YPK1_like	cd05585	619	918	2.9e-05
NP_004422	STKc_Sck1_like	cd05586	619	976	7.1e-05
NP_004422	STKc_SLK_like	cd06611	619	890	1.2e-07
NP_004422	PKc_MKK4	cd06616	619	895	1.8e-06
NP_004422	STKc_MOK	cd07831	619	887	1.8e-06
NP_004422	STKc_CDK4_6_like	cd07838	619	895	5.1e-06
NP_004422	STKc_CDK8_like	cd07842	619	906	4.7e-06
NP_004422	STKc_CDK4	cd07863	619	907	0.00022
NP_004422	STKc_CDC2L6	cd07867	619	906	0.00024
NP_004422	STKc_CDC2L1	cd07843	623	882	1.3e-05
NP_004422		cd00166	903	966	2.5e-21
NP_004422	Ephrin_lbd	pfam01404	28	201	4e-118
NP_004422	fn3	pfam00041	330	424	1.8e-17
NP_004422	fn3	pfam00041	437	519	5.9e-20
NP_004422	Pkinase	pfam00069	613	871	4.8e-37
NP_004422	SAM_1	pfam00536	902	966	1.4e-30
NP_004422	EPH_lbd	smart00615	28	200	2.4e-103
NP_004422	FN3	smart00060	329	422	2.3e-12
NP_004422	FN3	smart00060	436	516	1.4e-12
NP_004422	Pkinase_Tyr	pfam07714	613	871	1.6e-150
NP_004422	STYKc	smart00221	613	913	1.1e-56
NP_004422	TyrKc	smart00219	613	871	1.3e-137
NP_004422	S_TKc	smart00220	623	875	1.6e-43
NP_004422	SAM_2	pfam07647	901	966	1.8e-15
NP_004422	SAM	smart00454	901	968	1.6e-23

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258