Results for the protein: P09871

Results for the Protein: P09871

115205

716

C1S

NCBI, UniProt

C1S_HUMAN RecName: Full=Complement C1s subcomponent; AltName: Full=C1 esterase; AltName: Full=Complement component 1 subcomponent s; Contains: RecName: Full=Complement C1s subcomponent heavy chain; Contains: RecName: Full=Complement C1s subcomponent light chain; Flags: Precursor

			0 3 0 0 3

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

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To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: CUB - cd00041 CUB - pfam00431 CUB - smart00042 EGF_CA - smart00179 EGF_CA - cd00054 EGF - smart00181 EGF - cd00053 EGF - pfam00008 CCP - smart00032 CCP - cd00033 Sushi - pfam00084 Tryp_SPc - smart00020 Tryp_SPc - cd00190 Trypsin - pfam00089	Swiss-Prot Protein: P09871 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
EGF_CA	cd00054	4.2e-09	131	172
EGF	cd00053	4.7e-06	134	172
CUB	cd00041	1.6e-28	175	289
CCP	cd00033	4.8e-12	294	355
CCP	cd00033	3e-12	359	422
Tryp_SPc	cd00190	5.9e-81	438	678
CUB	pfam00431	2.5e-15	16	127
EGF	pfam00008	1.8e-05	135	170
CUB	pfam00431	8.9e-45	175	287
Sushi	pfam00084	4.1e-08	294	354
Sushi	pfam00084	3.5e-08	359	425
Trypsin	pfam00089	1.7e-64	438	675
CUB	smart00042	2.1e-37	21	127
EGF_CA	smart00179	2.1e-10	131	172
EGF	smart00181	3.2e-07	134	172
CUB	smart00042	7e-28	185	287
CCP	smart00032	7.1e-11	294	354
CCP	smart00032	6.9e-13	359	421
Tryp_SPc	smart00020	1.1e-77	437	675

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_033643	Polymorphism	p.ARG119HIS	N/A
Swiss-Prot	VAR_014565	Polymorphism	p.ARG383HIS	N/A
Swiss-Prot	VAR_033644	Polymorphism	p.VAL327LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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