Results for the protein: P29320

Results for the Protein: P29320

116241351

2042

EPHA3

NCBI, UniProt

EPHA3_HUMAN RecName: Full=Ephrin type-A receptor 3; AltName: Full=EPH-like kinase 4; Short=EK4; Short=hEK4; AltName: Full=HEK; Short=Human embryo kinase; AltName: Full=Tyrosine-protein kinase TYRO4; AltName: Full=Tyrosine-protein kinase receptor ETK1; Short=Eph-like tyrosine kinase 1; Flags: Precursor

			0 17 0 2 15

Tips:

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Swiss-Prot Protein: P29320

Identical to: NP_005224

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
FN3	cd00063	5.4e-20	437	528
PTKc_VEGFR	cd05054	2.4e-25	503	885
PTKc_CSF-1R	cd05106	4.3e-23	571	883
STKc_ROCK	cd05596	0.00078	579	939
STKc_ROCK1	cd05622	0.00094	579	940
STKc_ROCK2	cd05621	8.3e-05	579	945
STKc_PAK1	cd06654	0.00046	585	900
STKc_PAK4	cd06657	0.00023	586	909
PTKc_PDGFR	cd05055	5.9e-18	587	882
STKc_PAK3	cd06656	0.00043	590	901
PTKc_PDGFR_alpha	cd05105	2.7e-13	592	884
PTKc_PDGFR_beta	cd05107	1.8e-09	592	883
STKc_PAK_II	cd06648	3e-08	593	895
PTKc_Kit	cd05104	6.1e-17	594	882
STKc_PAK5	cd06658	0.0001	596	896
STKc_JNK	cd07850	5.8e-05	596	959
STKc_TAO1	cd06635	9.7e-05	599	905
PTKc_FGFR1	cd05098	9.4e-37	600	889
STKc_myosinIIIA	cd06638	0.00017	600	882
STKc_myosinIIIB	cd06639	0.00012	600	883
PTKc_FGFR2	cd05101	1.5e-43	601	889
STKc_TAO3	cd06633	0.0008	601	905
STKc_PAK6	cd06659	6e-07	601	913
STKc_PAK	cd06614	2.1e-13	602	895
STKc_TAO2	cd06634	4.1e-06	604	906
PTKc_FGFR4	cd05099	6.3e-44	605	899
STKc_TAO	cd06607	2.2e-05	606	914
PKc_MKK7	cd06618	6.3e-08	606	893
STKc_p38	cd07851	8.6e-06	606	915
STKc_CDK9	cd07865	3.4e-05	606	925
STKc_p38gamma_MAPK12	cd07880	8.4e-05	606	964
STKc_STK10_LOK	cd06644	1e-05	609	898
PTKc_FGFR3	cd05100	2.5e-34	610	935
STKc_ASK	cd06624	7.3e-11	610	882
STKc_PAK_I	cd06647	0.00012	610	900
STKc_PAK2	cd06655	0.0008	610	901
PTKc_DDR	cd05051	4.1e-51	611	880
PTK_Tyk2_rpt1	cd05076	2e-07	611	879
STKc_MAP4K3	cd06645	0.00015	611	879
STKc_MAP4K5	cd06646	0.00054	611	879
STKc_PCTAIRE2	cd07872	2.6e-05	611	935
STKc_PCTAIRE1	cd07873	9.1e-05	611	915
PTK_Ryk	cd05043	1.1e-24	612	881
PTKc_Tyk2_rpt2	cd05080	4.5e-21	612	883
STKc_PCTAIRE_like	cd07844	1.4e-06	612	913
STKc_Sty1_Hog1	cd07856	1.6e-06	612	935
STKc_PCTAIRE3	cd07871	3.2e-06	612	901
STKc_JNK3	cd07874	0.001	612	961
PTKc_EGFR_like	cd05057	4.4e-77	613	892
PTKc_VEGFR3	cd05102	6.5e-24	613	885
PTKc_VEGFR2	cd05103	5.2e-17	613	885
PTKc_EGFR	cd05108	7.9e-55	613	922
PTKc_HER2	cd05109	1.4e-60	613	892
PTKc_HER4	cd05110	1.4e-52	613	907
PTK_HER3	cd05111	3.4e-52	613	892
PTKc_ALK_LTK	cd05036	4.2e-68	614	880
PTKc_FAK	cd05056	2.4e-88	614	886
STKc_MAP4K4_6	cd06636	0.00012	614	878
STKc_TNIK	cd06637	3.2e-05	614	882
STKc_CDK12	cd07864	3e-10	614	902
PTKc_InsR_like	cd05032	5e-75	615	880
PTKc_Src_like	cd05034	1.4e-104	615	881
PTK_CCK4	cd05046	4.5e-38	615	880
PTKc_Ror	cd05048	1e-65	615	881
PTKc_Csk_like	cd05039	1.7e-72	615	881
PTKc_Trk	cd05049	4.2e-77	615	880
PTKc_Musk	cd05050	1.9e-75	615	880
PTKc_Abl	cd05052	1.1e-83	615	882
PTKc_FGFR	cd05053	3e-44	615	883
PTKc_InsR	cd05061	7.1e-55	615	893
PTKc_IGF-1R	cd05062	2.4e-55	615	879
PTKc_EphR_A2	cd05063	4e-195	615	882
PTKc_EphR_A10	cd05064	6.4e-154	615	882
PTKc_Lck_Blk	cd05067	1.9e-78	615	881
PTKc_Frk_like	cd05068	8.7e-100	615	881
PTKc_Yes	cd05069	1.4e-74	615	881
PTKc_Fyn_Yrk	cd05070	6.9e-76	615	881
PTKc_Src	cd05071	1.2e-75	615	883
PTKc_Lyn	cd05072	2.1e-79	615	881
PTKc_Hck	cd05073	1.7e-80	615	881
PTKc_Csk	cd05082	1.5e-62	615	881
PTKc_Ror1	cd05090	9e-58	615	881
PTKc_Ror2	cd05091	3.5e-55	615	881
PTKc_TrkB	cd05093	2.1e-57	615	889
PTKc_TrkA	cd05092	9.8e-60	615	880
PTKc_TrkC	cd05094	6.1e-34	615	889
PTKc_DDR2	cd05095	1.3e-57	615	880
PTKc_DDR1	cd05096	1.8e-46	615	880
PTKc_DDR_like	cd05097	1.6e-55	615	880
PTKc_Srm_Brk	cd05148	4.7e-78	615	881
PKc_MAPKK_Byr1_like	cd06620	7.6e-08	615	895
PKc_MEK2	cd06649	0.00063	615	933
STKc_ERK5	cd07855	0.00028	615	927
STKc_TEY_MAPK_plant	cd07858	2.5e-06	615	939
PTKc_EphR	cd05033	2.7e-232	616	882
PTKc_Jak_rpt2	cd05038	2.7e-72	616	882
PTKc_Tec_like	cd05059	4.5e-76	616	879
PTKc_EphR_B	cd05065	6.8e-197	616	882
PTKc_EphR_A	cd05066	1e-228	616	882
PTKc_Jak1_rpt2	cd05079	1.4e-40	616	882
PTKc_Jak2_Jak3_rpt2	cd05081	3.8e-44	616	882
PTKc_Chk	cd05083	1.8e-70	616	881
PTKc_Tie2	cd05088	1.9e-43	616	905
PTKc_Itk	cd05112	1.2e-69	616	879
PTKc_Btk_Bmx	cd05113	2.2e-76	616	879
PTKc_Tec_Rlk	cd05114	1.5e-74	616	879
STKc_myosinIII_like	cd06608	4.2e-09	616	877
PKc_MKK4	cd06616	5.6e-07	616	902
STKc_MAPK4_6	cd07854	0.00015	616	936
STKc_MAP4K3_like	cd06613	6.1e-11	617	879
STKc_MST4	cd06640	1.2e-07	617	889
STKc_STK25-YSK1	cd06642	9.8e-08	617	889
STKc_MST3	cd06641	8.9e-07	617	889
STKc_PFTAIRE2	cd07870	0.00025	617	913
STKc_MEKK3_like	cd06625	2.1e-09	618	880
STKc_MEKK3	cd06651	2.2e-06	618	882
STKc_MEKK2	cd06652	0.00041	618	873
STKc_MEKK3_like_1	cd06653	1.1e-05	618	880
STKc_ERK1_2_like	cd07849	4.2e-06	618	937
STKc_Nek6_Nek7	cd08224	1.8e-09	618	883
STKc_Nek6	cd08228	5.2e-07	618	883
STKc_Nek7	cd08229	5.5e-10	618	883
PTKc_Tie1	cd05089	1.1e-44	619	897
STKc_ROCK_NDR_like	cd05573	0.00033	619	938
STKc_PKA	cd05580	1.1e-06	619	902
STKc_PDK1	cd05581	1.1e-08	619	874
STKc_DMPK_like	cd05597	0.00011	619	938
STKc_CRIK	cd05601	3.2e-05	619	908
STKc_MAST	cd05609	0.00017	619	933
STKc_PRKX_like	cd05612	7.6e-06	619	903
STKc_MRCK_alpha	cd05623	0.00023	619	939
STKc_MRCK_beta	cd05624	0.0007	619	938
STKc_MST3_like	cd06609	8.5e-10	619	889
STKc_SLK_like	cd06611	1.4e-08	619	897
PKc_MEK	cd06615	6.6e-07	619	917
PKc_MKK3_6	cd06617	6.4e-07	619	893
PKc_MKK5	cd06619	1.2e-05	619	906
PKc_MAPKK_plant_like	cd06623	9e-13	619	887
STKc_CDKL5	cd07848	0.00077	619	913
STKc_CDK6	cd07862	0.00067	619	913
STKc_CDK1_euk	cd07861	0.00012	619	921
SPS1	COG0515	1.6e-24	619	981
PTKc_RET	cd05045	1.7e-51	620	885
STKc_Yank1	cd05578	4.1e-07	620	879
STKc_MSK_N	cd05583	0.00025	620	898
STKc_cPKC	cd05587	7e-05	620	939
STKc_GRK4_like	cd05605	5.7e-05	620	905
STKc_MSK2_N	cd05614	9.9e-05	620	961
STKc_cPKC_alpha	cd05615	5.3e-05	620	921
STKc_MAPKKK	cd06606	4.8e-18	620	872
STKc_Cdc7_like	cd06627	1.8e-16	620	874
STKc_MAPKKK_Byr2_lik	cd06628	2.6e-11	620	880
STKc_CCRK	cd07832	4.8e-07	620	902
STKc_MAPK	cd07834	1.4e-07	620	919
STKc_Pho85	cd07836	4.9e-06	620	901
STKc_CDK7	cd07841	1.1e-07	620	875
STKc_NLK	cd07853	8.6e-06	620	975
STKc_MPK1	cd07857	6.5e-06	620	886
STKc_TDY_MAPK_plant	cd07859	5.1e-06	620	964
STKc_Nek	cd08215	1.5e-16	620	882
STKc_Nek1	cd08218	1e-09	620	883
STKc_Nek3	cd08219	2e-10	620	878
STKc_Nek8	cd08220	3.3e-08	620	882
STKc_Nek4	cd08223	1.1e-07	620	882
STKc_Nek5	cd08225	9.7e-13	620	883
STKc_Nek11	cd08222	3.3e-11	620	882
STKc_Nek10	cd08528	1e-05	620	880
STKc_CNK2-like	cd08530	8.3e-08	620	878
PTKc_Axl_like	cd05035	1.9e-60	621	882
PTKc_Tyro3	cd05074	8.5e-53	621	882
PTKc_Axl	cd05075	6.5e-52	621	882
STKc_PKN	cd05589	1.3e-05	621	938
PKc_STE	cd05122	1.4e-14	622	873
STKc_MST1_2	cd06612	1.7e-12	622	874
STKc_CDK_like	cd07829	2.9e-09	622	896
STKc_CDK5	cd07839	1.4e-06	622	901
STKc_CDK9_like	cd07840	1.4e-10	622	902
STKc_CDC2L1	cd07843	6.8e-06	622	882
STKc_CDK10	cd07845	2.8e-06	622	914
STKc_CDKL1_4	cd07847	1.8e-06	622	913
STKc_CDK2_3	cd07860	0.00016	622	901
STKc_CDK4	cd07863	0.00014	622	902
PK_STRAD	cd08216	2.4e-05	622	884
STKc_OSR1_SPAK	cd06610	1.7e-09	623	878
STKc_CDK1_like	cd07835	3.4e-06	623	913
STKc_MAPK15	cd07852	0.00012	623	906
STKc_FA2-like	cd08529	2.5e-09	623	888
STKc_p70S6K	cd05584	5.9e-05	624	940
PKc_MAPKK	cd06605	6.7e-10	624	876
PKc_MAPKK_Pek1_like	cd06621	3.8e-07	624	884
PKc_MAPKK_PBS2_like	cd06622	1.3e-07	624	927
STKc_MEKK4	cd06626	4.7e-08	624	874
STKc_SLK	cd06643	1.5e-06	624	896
STKc_CDKL	cd07833	0.0003	624	876
STKc_CdkB_plant	cd07837	0.00031	624	904
STKc_CDKL2_3	cd07846	8.8e-05	624	871
PTKc	cd00192	2e-136	625	879
PTK_Jak_rpt1	cd05037	1.3e-11	625	879
PTKc_Ack_like	cd05040	8.2e-74	625	880
PTKc_Fes_like	cd05041	2.8e-93	625	880
PTKc_Aatyk	cd05042	5.2e-15	625	880
PTKc_c-ros	cd05044	5e-71	625	880
PTKc_Tie	cd05047	1.5e-51	625	883
PTKc_Met_Ron	cd05058	3.3e-67	625	884
PTKc_Syk_like	cd05060	1e-92	625	883
PTK_Jak1_rpt1	cd05077	1.4e-10	625	879
PTK_Jak2_Jak3_rpt1	cd05078	5.7e-12	625	879
PTKc_Fes	cd05084	1.5e-75	625	880
PTKc_Fer	cd05085	1.5e-75	625	880
PTKc_Aatyk2	cd05086	2.8e-21	625	880
PTKc_Aatyk1_Aatyk3	cd05087	8.7e-19	625	880
PTKc_Syk	cd05116	4.8e-64	625	883
STKc_CMGC	cd05118	3e-10	625	874
STKc_PKC	cd05570	2.3e-05	625	938
STKc_PKB	cd05571	1.8e-06	625	940
STKc_SGK	cd05575	8.9e-05	625	938
STKc_phototropin_lik	cd05574	1.2e-05	625	892
STKc_RSK_N	cd05582	7.9e-07	625	938
STKc_nPKC_epsilon	cd05591	4.3e-05	625	947
STKc_nPKC_theta_delt	cd05592	0.00011	625	948
STKc_PKB_gamma	cd05593	0.00049	625	943
STKc_PKB_alpha	cd05594	0.00024	625	941
STKc_SGK1	cd05602	0.00018	625	940
STKc_SGK2	cd05603	3.4e-05	625	939
STKc_nPKC_theta	cd05619	4.6e-05	625	961
STKc_MAPKKK_Bck1_lik	cd06629	1.1e-11	625	872
STKc_MEKK1	cd06630	5.5e-07	625	872
STKc_MEKK1_plant	cd06632	2.3e-10	625	875
STKc_YSK4	cd06631	1.6e-08	625	878
STKc_MAK_like	cd07830	2.4e-08	625	871
STKc_MOK	cd07831	2.8e-05	625	901
STKc_Nek2	cd08217	3e-08	625	882
STKc_NAK1_like	cd06917	3.6e-07	626	886
STKc_BUR1	cd07866	2.8e-07	626	896
STKc_Nek9	cd08221	1.7e-09	626	883
PKc	cd00180	6.3e-63	627	878
PTKc_Zap-70	cd05115	1.5e-74	627	883
STKc_AGC	cd05123	3.7e-08	627	874
STKc_cGK_PKG	cd05572	8.2e-06	627	863
STKc_YPK1_like	cd05585	7.6e-05	627	937
STKc_CDK4_6_like	cd07838	3.4e-05	627	861
STKc_MAST_like	cd05579	3.3e-06	645	861
	cd00166	6.9e-11	910	973
Ephrin_lbd	pfam01404	5.1e-129	29	202
fn3	pfam00041	4e-16	327	419
fn3	pfam00041	6.3e-18	438	521
Pkinase	pfam00069	2.2e-42	621	878
SAM_1	pfam00536	2.9e-15	909	973
EPH_lbd	smart00615	1.1e-119	29	201
GCC2_GCC3	pfam07699	0.0004	263	304
FN3	smart00060	1.3e-08	326	418
FN3	smart00060	1.1e-16	437	518
Pkinase_Tyr	pfam07714	3.3e-152	621	878
TyrKc	smart00219	8.8e-145	621	878
STYKc	smart00221	2.9e-63	621	925
S_TKc	smart00220	4.2e-48	631	882
SAM_2	pfam07647	6.3e-16	908	973
SAM	smart00454	3.4e-13	908	975

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_042133	Polymorphism	p.ALA777GLY	N/A
dbSNP	rs17801309	Polymorphism	p.ARG914HIS	N/A
Swiss-Prot	VAR_036087	Polymorphism	p.ASN85SER	N/A
Swiss-Prot	VAR_036089	Polymorphism	p.ASP806ASN	N/A
Swiss-Prot	VAR_042130	Polymorphism	p.CYS568SER	N/A
Swiss-Prot	VAR_042132	Polymorphism	p.GLY766GLU	N/A
Swiss-Prot	VAR_042128	Polymorphism	p.GLY518LEU	N/A
Swiss-Prot	VAR_036088	Polymorphism	p.ILE621LEU	N/A
Swiss-Prot	VAR_042129	Polymorphism	p.ILE564VAL	N/A
Swiss-Prot	VAR_042131	Polymorphism	p.LEU590PRO	N/A
Swiss-Prot	VAR_068853	Polymorphism	p.LYS207ASN	N/A
Swiss-Prot	VAR_042127	Polymorphism	p.SER449PHE	N/A
Swiss-Prot	VAR_042126	Polymorphism	p.SER229TYR	N/A
Swiss-Prot	VAR_036086	Polymorphism	p.THR37LYS	N/A
Swiss-Prot	VAR_065831	Polymorphism	p.THR660LYS	N/A
Swiss-Prot	VAR_065832	Polymorphism	p.THR933MET	N/A
dbSNP	rs35124509	Polymorphism	p.TRP924ARG	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258