Results for the protein: P42261

Results for the Protein: P42261

116242505

2890

GRIA1

NCBI, UniProt

GRIA1_HUMAN RecName: Full=Glutamate receptor 1; Short=GluR-1; AltName: Full=AMPA-selective glutamate receptor 1; AltName: Full=GluR-A; AltName: Full=GluR-K1; AltName: Full=Glutamate receptor ionotropic, AMPA 1; Short=GluA1; Flags: Precursor

Known Diseases associated with this Protein:
VARIANT OF UNKNOWN SIGNIFICANCE

1

5

1

0

5

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Swiss-Prot Protein: P42261

Identical to: NP_000818

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PBP1_iGluR_Kainate_G	cd06393	1.4e-24	23	391
Periplasmic_Binding_	cd01391	3.1e-35	26	366
PBP1_ABC_transporter	cd04509	7.5e-59	26	367
PBP1_glutamate_recep	cd06269	1.5e-65	26	389
PBP1_GPCR_family_C_l	cd06350	8.3e-06	26	392
PBP1_iGluR_N_LIVBP_l	cd06351	1.5e-119	26	389
PBP1_GABAb_receptor	cd06366	3.9e-08	26	392
PBP1_iGluR_non_NMDA_	cd06368	5.9e-159	26	389
PBP1_iGluR_AMPA	cd06380	3.1e-212	26	389
PBP1_iGluR_delta_lik	cd06381	7.2e-06	26	389
PBP1_iGluR_Kainate	cd06382	1.3e-47	26	389
PBP1_iGluR_AMPA_GluR	cd06389	1.5e-182	26	390
PBP1_iGluR_AMPA_GluR	cd06390	6.3e-302	26	389
PBP1_iGluR_delta_2	cd06391	1.5e-06	26	390
PBP1_iGluR_AMPA_GluR	cd06388	7.9e-170	26	390
PBP1_iGluR_AMPA_GluR	cd06387	1.1e-166	26	389
PBPb	cd00134	3.9e-05	409	781
ANF_receptor	pfam01094	5e-65	37	372
SBP_bac_3	pfam00497	9.5e-19	409	783
Lig_chan	pfam00060	4e-153	536	817
Lig_chan-Glu_bd	pfam10613	3.3e-35	418	483
PBPe	smart00079	5.2e-68	646	783

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_028073	Polymorphism	p.ALA536SER	N/A
Swiss-Prot	VAR_028071	Polymorphism	p.ASP487ASN	N/A
Swiss-Prot	VAR_028074	Polymorphism	p.ILE548MET	N/A
Swiss-Prot	VAR_028075	Polymorphism	p.PHE588LEU	N/A
Swiss-Prot	VAR_028072	Polymorphism	p.PRO521THR	N/A
OMIM	138248.0001	Disease	p.ALA626THR	VARIANT OF UNKNOWN SIGNIFICANCE

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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