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Results for the Protein: P01375
135934
TNF

TNFA_HUMAN RecName: Full=Tumor necrosis factor; AltName: Full=Cachectin; AltName: Full=TNF-alpha; AltName: Full=Tumor necrosis factor ligand superfamily member 2; Short=TNF-a; Contains: RecName: Full=Tumor necrosis factor, membrane form; AltName: Full=N-terminal fragment; Short=NTF; Contains: RecName: Full=Intracellular domain 1; Short=ICD1; Contains: RecName: Full=Intracellular domain 2; Short=ICD2; Contains: RecName: Full=C-domain 1; Contains: RecName: Full=C-domain 2; Contains: RecName: Full=Tumor necrosis factor, soluble form; Flags: Precursor

Known Diseases associated with this Protein:
  TNF RECEPTOR BINDING, ALTERED
2
2
2
0
2
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Default View:

TNF - cd00184
TNF - smart00207
TNF - pfam00229


Swiss-Prot Protein: P01375
Identical to: NP_000585
   Default View:





Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
TNFpfam002297.8e-60102233
TNFsmart002074.7e-53102233

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_011927Polymorphismp.ALA94THRN/A
Swiss-ProtVAR_019378Polymorphismp.PRO84LEUN/A
OMIM191160.0002 Diseasep.ARG32TRPTNF RECEPTOR BINDING, ALTERED
OMIM191160.0001 Diseasep.LEU29SERTNF RECEPTOR BINDING, ALTERED



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