Results for the protein: Q13177

Results for the Protein: Q13177

143811432

5062

PAK2

NCBI, UniProt

PAK2_HUMAN RecName: Full=Serine/threonine-protein kinase PAK 2; AltName: Full=Gamma-PAK; AltName: Full=PAK65; AltName: Full=S6/H4 kinase; AltName: Full=p21-activated kinase 2; Short=PAK-2; AltName: Full=p58; Contains: RecName: Full=PAK-2p27; Short=p27; Contains: RecName: Full=PAK-2p34; Short=p34; AltName: Full=C-t-PAK2

			0 2 0 2 0

Tips:

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Swiss-Prot Protein: Q13177

Identical to: NP_002568

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
CRIB_PAK_like	cd01093	1e-28	72	117
STKc_ROCK	cd05596	5e-07	200	523
STKc_ROCK2	cd05621	3e-07	200	524
STKc_ROCK1	cd05622	1.8e-06	209	523
STKc_JNK1	cd07875	1.9e-07	218	523
STKc_TAO1	cd06635	4e-45	219	523
STKc_TAO3	cd06633	1.1e-45	223	523
STKc_PAK5	cd06658	9.9e-116	226	517
PTKc_FGFR1	cd05098	3.4e-05	227	511
STKc_PAK6	cd06659	6.8e-114	227	523
STKc_PAK1	cd06654	1.2e-255	228	523
STKc_PAK4	cd06657	5.1e-119	228	519
STKc_PAK	cd06614	1.3e-201	229	513
STKc_TAO2	cd06634	9.3e-45	229	523
STKc_PAK_I	cd06647	8.3e-239	229	521
STKc_PAK_II	cd06648	3.1e-152	229	513
STKc_PAK2	cd06655	2.5e-274	229	524
STKc_PAK3	cd06656	2.2e-253	229	524
STKc_TAO	cd06607	2.4e-57	229	524
PTKc_Ror	cd05048	5.2e-07	230	452
PTKc_Ror2	cd05091	0.00039	230	503
STKc_myosinIIIB	cd06639	9.8e-55	231	501
STKc_JNK2	cd07876	6.9e-08	231	521
STKc_p38alpha_MAPK14	cd07877	1.3e-05	231	519
STKc_myosinIIIA	cd06638	3.8e-59	232	500
STKc_p38gamma_MAPK12	cd07880	5.1e-08	232	522
STKc_STK10_LOK	cd06644	5e-59	233	520
STKc_p38	cd07851	1.2e-11	233	524
STKc_p38beta_MAPK11	cd07878	1.3e-06	233	522
STKc_p38delta_MAPK13	cd07879	0.00013	233	524
STKc_MAP4K4_6	cd06636	5.3e-55	234	500
PTKc_PDGFR	cd05055	7e-05	235	502
PTKc_FGFR2	cd05101	1.2e-05	235	507
STKc_CDK9	cd07865	5.4e-13	235	500
PTKc_FGFR4	cd05099	2.3e-06	236	522
PTKc_HER4	cd05110	1.9e-05	236	519
STKc_JNK	cd07850	2.3e-09	236	524
STKc_Sty1_Hog1	cd07856	9.7e-11	238	523
PKc_MKK7	cd06618	1.1e-14	239	516
STKc_BUR1	cd07866	4e-11	239	500
STKc_ASK	cd06624	1.6e-45	240	500
STKc_MAP4K3	cd06645	4.4e-67	240	499
STKc_MAP4K5	cd06646	4.6e-62	240	499
STKc_JNK3	cd07874	2.8e-07	240	521
STKc_ERK5	cd07855	1.5e-09	241	523
PTKc_FAK	cd05056	1.8e-08	242	504
STKc_myosinIII_like	cd06608	1.9e-76	242	500
STKc_TNIK	cd06637	2.4e-53	242	500
STKc_PFTAIRE2	cd07870	5.9e-09	242	500
PTKc_FGFR3	cd05100	0.00027	243	523
STKc_SLK_like	cd06611	4.1e-63	243	512
STKc_SLK	cd06643	2.5e-63	243	518
STKc_PCTAIRE2	cd07872	3.1e-08	243	517
STKc_PCTAIRE1	cd07873	2.6e-07	243	511
PTKc_FGFR	cd05053	3.9e-08	244	503
PTKc_EphR_A10	cd05064	0.00019	244	506
PTKc_Itk	cd05112	4e-10	244	499
PTKc_Tec_Rlk	cd05114	8.8e-11	244	499
PKc_MAPKK_Byr1_like	cd06620	4.7e-11	244	510
STKc_MST4	cd06640	2.4e-77	244	520
STKc_MST3	cd06641	1.6e-75	244	520
STKc_STK25-YSK1	cd06642	1.3e-76	244	520
STKc_PCTAIRE_like	cd07844	1.2e-14	244	523
STKc_ERK1_2_like	cd07849	3.2e-09	244	521
STKc_MAPK4_6	cd07854	1.6e-07	244	524
STKc_TEY_MAPK_plant	cd07858	9.9e-07	244	524
PTKc_InsR_like	cd05032	5.2e-10	245	502
PTKc_EphR	cd05033	4.7e-06	245	503
PTKc_Src_like	cd05034	1.5e-08	245	502
PTKc_ALK_LTK	cd05036	1.6e-11	245	500
PTKc_Jak_rpt2	cd05038	5.6e-09	245	503
PTKc_Csk_like	cd05039	9.8e-08	245	498
PTKc_Trk	cd05049	1.7e-06	245	497
PTKc_Musk	cd05050	6.7e-08	245	497
PTKc_Abl	cd05052	5.7e-09	245	503
PTKc_InsR	cd05061	9.5e-08	245	509
PTKc_Lck_Blk	cd05067	5.8e-06	245	509
PTKc_Frk_like	cd05068	1.6e-12	245	502
PTKc_Yes	cd05069	7e-07	245	503
PTKc_Fyn_Yrk	cd05070	3.6e-06	245	503
PTKc_Lyn	cd05072	9.5e-06	245	502
PTKc_Hck	cd05073	1.4e-06	245	502
PTKc_Tie2	cd05088	0.00011	245	522
PTKc_Ror1	cd05090	4.8e-05	245	503
PTKc_DDR_like	cd05097	8.5e-05	245	502
PTKc_DDR2	cd05095	3.6e-05	245	491
PTKc_Btk_Bmx	cd05113	8.9e-11	245	499
PTKc_DDR	cd05051	0.00041	245	502
PTKc_IGF-1R	cd05062	1.3e-07	245	502
PTKc_Srm_Brk	cd05148	4.4e-08	245	509
PTKc_Src	cd05071	8.1e-06	245	505
STKc_MST1_2	cd06612	3.5e-88	245	500
STKc_MAP4K3_like	cd06613	8.9e-101	245	499
PTKc_Tec_like	cd05059	5.2e-11	246	499
PTKc_EphR_B	cd05065	0.00012	246	503
PTKc_EphR_A	cd05066	0.00044	246	503
PTKc_Jak1_rpt2	cd05079	0.00016	246	503
PTKc_Tyk2_rpt2	cd05080	5.4e-07	246	505
PTKc_Jak2_Jak3_rpt2	cd05081	5e-08	246	504
PTKc_Csk	cd05082	6.4e-10	246	498
PTKc_TrkA	cd05092	5.9e-06	246	504
PTKc_TrkB	cd05093	1.2e-05	246	515
PTK_HER3	cd05111	3.2e-07	246	515
PKc_MEK2	cd06649	8.3e-08	246	515
STKc_MEKK3_like_1	cd06653	3.9e-27	246	500
PKc_MEK1	cd06650	8.6e-08	246	523
STKc_PFTAIRE1	cd07869	2.1e-05	246	511
STKc_Nek6_Nek7	cd08224	8e-17	246	508
PTKc_EphR_A2	cd05063	0.00021	247	503
PTKc_Tie1	cd05089	0.00012	247	522
PTKc_Chk	cd05083	5.9e-08	247	505
STKc_ROCK_NDR_like	cd05573	2.6e-14	247	524
STKc_phototropin_lik	cd05574	8e-11	247	521
STKc_PKA	cd05580	1.3e-16	247	524
STKc_PDK1	cd05581	3e-26	247	500
STKc_DMPK_like	cd05597	2.1e-06	247	523
STKc_LATS	cd05598	1.4e-07	247	524
STKc_Sid2p_Dbf2p	cd05600	2.7e-07	247	524
STKc_CRIK	cd05601	2.9e-09	247	523
STKc_MAST	cd05609	1.9e-11	247	523
STKc_PRKX_like	cd05612	3.6e-14	247	523
STKc_MRCK_alpha	cd05623	1.5e-06	247	522
STKc_MRCK_beta	cd05624	1.2e-05	247	518
STKc_LATS1	cd05625	1.5e-05	247	524
STKc_NDR2	cd05627	0.00045	247	524
STKc_NDR1	cd05628	2.6e-05	247	524
STKc_NDR_like_fungal	cd05629	0.00024	247	524
STKc_LATS2	cd05626	2.4e-05	247	524
PKc_MAPKK	cd06605	4.4e-22	247	505
STKc_MST3_like	cd06609	5.2e-99	247	520
STKc_OSR1_SPAK	cd06610	9.2e-83	247	500
PKc_MEK	cd06615	1.9e-13	247	520
PKc_MKK5	cd06619	5.8e-21	247	524
PKc_MAPKK_Pek1_like	cd06621	7.3e-17	247	510
PKc_MAPKK_PBS2_like	cd06622	2.4e-13	247	523
PKc_MAPKK_plant_like	cd06623	8.2e-47	247	505
STKc_MEKK3_like	cd06625	7.5e-53	247	500
PKc_MKK3_6	cd06617	9.1e-16	247	515
STKc_NAK1_like	cd06917	4.8e-74	247	517
STKc_CDKL	cd07833	2.6e-16	247	500
STKc_CdkB_plant	cd07837	7.6e-14	247	501
STKc_CDC2L1	cd07843	5.2e-13	247	500
STKc_CDK10	cd07845	1.1e-13	247	514
STKc_CDKL2_3	cd07846	1e-14	247	500
STKc_CDKL1_4	cd07847	8.3e-33	247	500
STKc_CDKL5	cd07848	5.5e-06	247	500
STKc_MAPK15	cd07852	9.3e-12	247	520
STKc_CDK6	cd07862	1.4e-07	247	500
STKc_CDK12	cd07864	7.2e-13	247	500
STKc_PCTAIRE3	cd07871	3.3e-08	247	500
STKc_Nek6	cd08228	2.4e-19	247	502
STKc_Nek7	cd08229	1.9e-14	247	508
SPS1	COG0515	3.8e-47	247	523
PTKc_RET	cd05045	3.6e-05	248	506
PTKc_EGFR_like	cd05057	3.3e-07	248	512
PTKc_EGFR	cd05108	2.9e-06	248	524
PTKc_HER2	cd05109	1.2e-07	248	513
PKc_STE	cd05122	4.9e-151	248	499
STKc_Yank1	cd05578	5.7e-20	248	500
STKc_MSK_N	cd05583	4.5e-13	248	519
STKc_cPKC	cd05587	2e-07	248	523
STKc_GRK4_like	cd05605	1.1e-10	248	524
STKc_MSK1_N	cd05613	1.1e-08	248	511
STKc_MSK2_N	cd05614	1.3e-08	248	522
STKc_cPKC_alpha	cd05615	6.6e-08	248	523
STKc_cPKC_beta	cd05616	1.2e-05	248	524
STKc_GRK6	cd05630	7.7e-08	248	522
STKc_GRK4	cd05631	1.1e-07	248	517
STKc_GRK5	cd05632	1e-08	248	522
STKc_MAPKKK	cd06606	1.4e-89	248	500
STKc_MEKK4	cd06626	4.2e-37	248	500
STKc_MAPKKK_Byr2_lik	cd06628	1.7e-53	248	500
STKc_MAPKKK_Bck1_lik	cd06629	1e-20	248	500
STKc_Cdc7_like	cd06627	5.2e-78	248	500
STKc_MEKK1	cd06630	1.2e-31	248	501
STKc_YSK4	cd06631	7e-37	248	500
STKc_MEKK3	cd06651	3.8e-36	248	502
STKc_CCRK	cd07832	4.2e-18	248	501
STKc_MAPK	cd07834	6e-13	248	523
STKc_Pho85	cd07836	2e-24	248	523
STKc_CDK5	cd07839	6.7e-11	248	500
STKc_CDK8_like	cd07842	6.1e-10	248	500
STKc_NLK	cd07853	1e-06	248	523
STKc_MPK1	cd07857	5.9e-09	248	519
STKc_TDY_MAPK_plant	cd07859	2.1e-08	248	524
STKc_CDK2_3	cd07860	3.1e-23	248	500
STKc_CDK1_euk	cd07861	5.8e-20	248	500
STKc_CDK4	cd07863	2.2e-13	248	500
STKc_Nek	cd08215	1.5e-45	248	500
STKc_Nek2	cd08217	2.1e-19	248	500
STKc_Nek1	cd08218	1e-30	248	500
STKc_Nek3	cd08219	1.3e-21	248	500
STKc_Nek8	cd08220	1.1e-32	248	500
STKc_CDK7	cd07841	8.8e-20	248	514
STKc_Nek11	cd08222	4.3e-24	248	500
STKc_Nek5	cd08225	1.1e-34	248	500
STKc_Nek4	cd08223	1.3e-24	248	500
STKc_Nek10	cd08528	1.8e-18	248	493
STKc_FA2-like	cd08529	3.8e-18	248	500
STKc_CNK2-like	cd08530	1.4e-14	248	500
PTKc_Tyro3	cd05074	5.7e-05	249	502
PTKc_Axl	cd05075	0.00067	249	502
STKc_CMGC	cd05118	8.9e-20	249	500
STKc_PKN	cd05589	9.8e-10	249	524
PKc_MKK4	cd06616	7.7e-14	249	520
STKc_MAK_like	cd07830	1.3e-16	249	500
STKc_MOK	cd07831	4.1e-13	249	500
STKc_CDK1_like	cd07835	7.7e-19	249	500
STKc_CDK4_6_like	cd07838	4.6e-17	249	500
STKc_CDK9_like	cd07840	4.1e-18	249	500
STKc_CDC2L6	cd07867	9.6e-05	249	500
STKc_CDK8	cd07868	7.4e-05	249	500
STKc_CDK_like	cd07829	1.8e-22	249	500
PK_STRAD	cd08216	2.5e-15	250	515
PK_STRAD_beta	cd08226	2.4e-06	250	515
PK_STRAD_alpha	cd08227	1.4e-07	250	515
STKc_MEKK2	cd06652	5.1e-26	251	501
STKc_Nek9	cd08221	5.4e-21	251	500
STKc_RSK_N	cd05582	3.6e-06	252	524
STKc_p70S6K	cd05584	7e-12	252	524
PTKc	cd00192	2.2e-25	253	499
PTKc_Ack_like	cd05040	2.5e-10	253	496
PTKc_Fes_like	cd05041	5.1e-13	253	502
PTKc_Aatyk	cd05042	3.7e-06	253	497
PTKc_c-ros	cd05044	1.9e-07	253	497
PTKc_Tie	cd05047	3.7e-05	253	507
PTKc_Met_Ron	cd05058	7e-07	253	504
PTKc_Syk_like	cd05060	1.1e-07	253	511
PTK_Jak2_Jak3_rpt1	cd05078	0.00025	253	499
PTKc_Fes	cd05084	1e-08	253	500
PTKc_Fer	cd05085	5.4e-07	253	500
PTKc_Syk	cd05116	5.1e-07	253	500
STKc_PKC	cd05570	6.3e-14	253	520
STKc_PKB	cd05571	1.6e-11	253	524
STKc_SGK	cd05575	5.5e-08	253	524
STKc_aPKC	cd05588	1.1e-07	253	523
STKc_nPKC_eta	cd05590	7.3e-08	253	522
STKc_nPKC_epsilon	cd05591	5e-10	253	523
STKc_nPKC_theta_delt	cd05592	4.7e-09	253	524
STKc_PKB_gamma	cd05593	5e-09	253	524
STKc_PKB_alpha	cd05594	1.9e-10	253	523
STKc_PKB_beta	cd05595	3e-08	253	524
STKc_SGK1	cd05602	3.3e-08	253	524
STKc_SGK3	cd05604	1.2e-05	253	520
STKc_aPKC_zeta	cd05617	2.3e-07	253	523
STKc_aPKC_iota	cd05618	1.7e-05	253	524
STKc_nPKC_theta	cd05619	2.3e-09	253	523
STKc_nPKC_delta	cd05620	8.3e-06	253	524
STKc_SGK2	cd05603	1.1e-09	253	523
STKc_MEKK1_plant	cd06632	1.8e-45	253	500
PTKc_Zap-70	cd05115	3.5e-06	254	503
PKc	cd00180	5.3e-86	255	498
PTKc_Axl_like	cd05035	4.4e-06	255	510
STKc_AGC	cd05123	1.8e-33	255	500
STKc_cGK_PKG	cd05572	1.6e-15	255	501
STKc_GRK	cd05577	1.2e-11	255	516
STKc_MAST_like	cd05579	1.1e-21	255	501
STKc_YPK1_like	cd05585	3.1e-09	255	523
STKc_Sck1_like	cd05586	2.7e-05	255	522
STKc_NDR_like	cd05599	9.8e-10	255	524
STKc_beta_ARK	cd05606	6.6e-09	255	516
STKc_GRK7	cd05607	2.5e-07	255	520
STKc_GRK1	cd05608	3.3e-11	255	520
STKc_Rim15_like	cd05611	6.2e-08	255	506
STKc_GRK3	cd05633	4.5e-08	255	513
PBD	pfam00786	2.1e-30	73	131
Pkinase	pfam00069	1.5e-94	249	500
PBD	smart00285	2.9e-17	74	109
Pkinase_Tyr	pfam07714	2.7e-20	249	500
STYKc	smart00221	4e-90	249	500
TyrKc	smart00219	1e-23	249	500
S_TKc	smart00220	6.5e-97	259	500
KIND	smart00750	1.3e-76	329	508

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs201465227	Polymorphism	p.GLN101HIS	N/A
dbSNP	rs78043821	Polymorphism	p.LYS128ARG	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258