Results for the protein: Q6VAB6

Results for the Protein: Q6VAB6

148886599

283455

KSR2

NCBI, UniProt

KSR2_HUMAN RecName: Full=Kinase suppressor of Ras 2; Short=hKSR2

			0 1 0 0 1

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: Q6VAB6

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTKc_PDGFR	cd05055	9.1e-05	634	932
STKc_PAK6	cd06659	4.3e-05	640	938
STKc_myosinIIIA	cd06638	2.5e-06	645	930
STKc_myosinIIIB	cd06639	5.7e-05	645	930
STKc_PAK	cd06614	1.5e-10	646	942
STKc_PAK_II	cd06648	0.00021	647	941
STKc_MAP4K4_6	cd06636	9.4e-06	649	930
PTKc_FGFR1	cd05098	0.00039	650	939
STKc_PAK1	cd06654	0.00075	650	949
STKc_PAK_I	cd06647	0.00019	651	950
STKc_PAK2	cd06655	0.0008	651	936
PKc_MKK7	cd06618	1.8e-05	653	950
PTKc_TrkA	cd05092	0.00036	655	933
PTKc_FGFR4	cd05099	1.5e-05	655	947
PTKc_EGFR	cd05108	5.3e-05	655	950
STKc_STK10_LOK	cd06644	3.2e-06	655	950
PTKc_FGFR	cd05053	2.2e-06	657	933
STKc_ASK	cd06624	1.1e-07	657	928
STKc_CDK9	cd07865	3.5e-05	657	944
PTKc_FGFR2	cd05101	0.00021	658	939
PTKc_VEGFR2	cd05103	0.00017	658	935
PTKc_VEGFR3	cd05102	0.00012	658	935
PTKc_InsR_like	cd05032	1.8e-08	659	930
PTKc_Src_like	cd05034	6.2e-11	659	931
PTKc_ALK_LTK	cd05036	6e-08	659	930
PTKc_Csk_like	cd05039	5.6e-10	659	931
PTKc_Abl	cd05052	1.7e-10	659	932
PTKc_FAK	cd05056	1e-08	659	936
PTKc_EGFR_like	cd05057	1.5e-09	659	939
PTKc_InsR	cd05061	2.9e-07	659	940
PTKc_IGF-1R	cd05062	1.3e-06	659	930
PTKc_Lck_Blk	cd05067	7.5e-07	659	931
PTKc_Frk_like	cd05068	6.9e-23	659	931
PTKc_Yes	cd05069	3.9e-08	659	931
PTKc_Fyn_Yrk	cd05070	1.7e-07	659	931
PTKc_Src	cd05071	2.6e-07	659	933
PTKc_Lyn	cd05072	1.1e-07	659	931
PTKc_Csk	cd05082	2.3e-10	659	931
PTKc_Chk	cd05083	2e-11	659	931
PTKc_Hck	cd05073	4.6e-08	659	931
PTKc_Srm_Brk	cd05148	7.6e-11	659	931
STKc_TNIK	cd06637	5.1e-07	659	930
STKc_CDK12	cd07864	0.00023	659	946
PTK_CCK4	cd05046	3.9e-07	660	930
PTKc_Ror	cd05048	5.5e-08	660	931
PTKc_Trk	cd05049	1e-06	660	933
PTKc_Musk	cd05050	4.1e-07	660	930
PTKc_DDR	cd05051	1.8e-07	660	930
PTKc_EphR_A2	cd05063	9.7e-06	660	932
PTKc_EphR_A10	cd05064	4.4e-06	660	932
PTKc_Ror1	cd05090	0.00068	660	931
PTKc_Ror2	cd05091	8.5e-06	660	931
PTKc_TrkB	cd05093	8.2e-05	660	940
PTKc_TrkC	cd05094	0.00076	660	940
PTKc_DDR2	cd05095	1.2e-05	660	930
PTKc_DDR_like	cd05097	3.9e-05	660	930
STKc_MAP4K3	cd06645	3.7e-07	660	929
STKc_MAP4K5	cd06646	2.2e-06	660	929
STKc_SLK	cd06643	3.1e-06	660	947
PTKc_Jak_rpt2	cd05038	1.4e-10	661	932
PTK_Ryk	cd05043	7e-06	661	931
PTKc_Tec_like	cd05059	6.5e-10	661	929
PTKc_EphR_B	cd05065	4.3e-06	661	932
PTKc_EphR_A	cd05066	9.1e-06	661	932
PTKc_Tie2	cd05088	0.0002	661	950
PTKc_EphR	cd05033	2e-08	661	932
PTKc_HER2	cd05109	1.6e-07	661	942
PTKc_Itk	cd05112	3e-09	661	929
PTKc_Btk_Bmx	cd05113	2.3e-10	661	929
PTKc_Tec_Rlk	cd05114	5.5e-08	661	929
PTK_HER3	cd05111	5.7e-07	661	939
STKc_NAK1_like	cd06917	8.1e-08	661	932
STKc_myosinIII_like	cd06608	8.4e-08	662	928
STKc_SLK_like	cd06611	8.1e-07	662	941
STKc_MST1_2	cd06612	7.6e-11	662	927
STKc_MAP4K3_like	cd06613	2.9e-10	662	928
STKc_MST4	cd06640	2.9e-06	662	949
STKc_MST3	cd06641	1.7e-06	662	946
STKc_STK25-YSK1	cd06642	1.9e-07	662	939
STKc_Pho85	cd07836	0.00034	662	946
STKc_PCTAIRE_like	cd07844	0.00088	662	949
PTKc_Jak1_rpt2	cd05079	0.00012	663	932
PTKc_Tyk2_rpt2	cd05080	5.4e-07	663	933
PTKc_Jak2_Jak3_rpt2	cd05081	5.7e-10	663	932
PTKc_Tie1	cd05089	0.0008	663	950
PTKc_HER4	cd05110	7.1e-05	663	950
STKc_CMGC	cd05118	1e-07	663	928
STKc_CDK1_like	cd07835	0.0009	663	944
STKc_CDK9_like	cd07840	3.2e-05	663	921
STKc_CDK10	cd07845	0.00027	663	922
STKc_Nek6_Nek7	cd08224	2.9e-05	663	933
STKc_Nek6	cd08228	0.00038	663	933
STKc_Nek7	cd08229	1.1e-05	663	933
STKc_PDK1	cd05581	5e-09	664	909
PKc_MAPKK	cd06605	7.3e-07	664	933
STKc_MST3_like	cd06609	3.2e-08	664	875
STKc_OSR1_SPAK	cd06610	2.1e-09	664	925
PKc_MKK4	cd06616	3.2e-06	664	950
PKc_MAPKK_PBS2_like	cd06622	7.1e-06	664	947
PKc_MAPKK_plant_like	cd06623	2.1e-08	664	933
STKc_MEKK3_like_1	cd06653	6.7e-06	664	930
PKc_MKK3_6	cd06617	3.8e-07	664	947
STKc_CdkB_plant	cd07837	0.00018	664	945
STKc_CDKL2_3	cd07846	0.00019	664	944
PTKc_RET	cd05045	5.2e-06	665	935
PKc_STE	cd05122	1.7e-12	665	926
STKc_Yank1	cd05578	2.7e-05	665	934
STKc_MSK_N	cd05583	0.00016	665	944
STKc_MAPKKK	cd06606	1.4e-15	665	930
STKc_Cdc7_like	cd06627	3.1e-10	665	925
STKc_MAPKKK_Byr2_lik	cd06628	2.2e-15	665	930
STKc_MEKK1	cd06630	2.3e-05	665	922
STKc_YSK4	cd06631	8.7e-10	665	928
STKc_MEKK3	cd06651	2.4e-06	665	931
STKc_CCRK	cd07832	4.9e-07	665	922
STKc_CDK7	cd07841	1.5e-06	665	932
STKc_CDK5	cd07839	0.00051	665	944
STKc_Nek	cd08215	4.2e-13	665	928
STKc_Nek2	cd08217	1.9e-05	665	930
STKc_Nek1	cd08218	5.6e-06	665	928
STKc_Nek3	cd08219	5.4e-09	665	930
STKc_Nek11	cd08222	9.1e-06	665	930
STKc_Nek4	cd08223	1.2e-05	665	930
STKc_Nek8	cd08220	3.1e-07	665	929
STKc_Nek5	cd08225	7.8e-06	665	928
STKc_Nek10	cd08528	1.9e-07	665	930
STKc_FA2-like	cd08529	3.5e-10	665	928
STKc_CNK2-like	cd08530	1.1e-06	665	928
PTKc_Axl_like	cd05035	1.6e-07	666	932
PTKc_Axl	cd05075	3.4e-05	666	932
PTKc_Aatyk1_Aatyk3	cd05087	0.00012	666	930
PTKc_Tyro3	cd05074	6.2e-06	666	932
STKc_MAK_like	cd07830	0.00031	666	930
STKc_CDK_like	cd07829	3.2e-06	666	928
STKc_CDK4_6_like	cd07838	2.3e-05	666	921
STKc_MEKK3_like	cd06625	2e-10	667	930
STKc_CDK8_like	cd07842	0.00068	667	944
PTKc_Syk	cd05116	2.6e-06	669	933
STKc_MEKK4	cd06626	1.9e-10	669	922
STKc_MAPKKK_Bck1_lik	cd06629	3.2e-09	669	922
STKc_MEKK1_plant	cd06632	2.9e-08	669	926
PTKc	cd00192	9.2e-17	670	929
PTK_Jak_rpt1	cd05037	0.00026	670	929
PTKc_Ack_like	cd05040	1.5e-13	670	930
PTKc_Fes_like	cd05041	1.6e-11	670	930
PTKc_Aatyk	cd05042	2e-06	670	930
PTKc_Tie	cd05047	0.00052	670	933
PTKc_Met_Ron	cd05058	2.2e-06	670	934
PTKc_Syk_like	cd05060	6.6e-08	670	933
PTKc_Fes	cd05084	1e-07	670	930
PTKc_Aatyk2	cd05086	2.2e-05	670	930
PTKc_Fer	cd05085	2.1e-08	670	930
PTKc_c-ros	cd05044	8.7e-06	670	930
STKc_PKC	cd05570	0.00059	670	939
STKc_beta_ARK	cd05606	9.5e-05	671	941
STKc_Nek9	cd08221	1.3e-05	671	932
PKc	cd00180	6.3e-47	672	928
PTKc_Zap-70	cd05115	4.9e-07	672	933
STKc_AGC	cd05123	2.7e-05	672	928
STKc_cGK_PKG	cd05572	0.00061	672	917
STKc_GRK	cd05577	0.00012	672	933
STKc_MAST_like	cd05579	6.2e-07	672	922
STKc_MOK	cd07831	0.00042	672	925
C1_1	pfam00130	0.00052	413	460
Pkinase	pfam00069	1.9e-35	666	928
C1	smart00109	3.3e-08	413	456
Pkinase_Tyr	pfam07714	6.9e-38	666	928
TyrKc	smart00219	2.2e-14	666	928
STYKc	smart00221	3.7e-34	666	930
S_TKc	smart00220	3.9e-28	676	930

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040659	Polymorphism	p.ARG676SER	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258