Results for the protein: Q92630

Results for the Protein: Q92630

148887370

8445

DYRK2

NCBI, UniProt

DYRK2_HUMAN RecName: Full=Dual specificity tyrosine-phosphorylation-regulated kinase 2

			0 6 0 0 6

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Swiss-Prot Protein: Q92630

Identical to: NP_006473

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_TAO1	cd06635	8.5e-05	196	510
STKc_PAK1	cd06654	4.5e-05	199	484
STKc_PAK3	cd06656	4.1e-06	200	565
STKc_JNK1	cd07875	3e-09	200	575
STKc_myosinIIIB	cd06639	2.5e-07	201	477
STKc_PAK6	cd06659	6.8e-06	202	503
STKc_PAK5	cd06658	8.9e-05	202	497
STKc_JNK2	cd07876	1.1e-11	202	573
STKc_myosinIIIA	cd06638	1.5e-07	203	476
STKc_PAK4	cd06657	0.00026	203	486
STKc_PAK_I	cd06647	3.9e-05	204	558
STKc_PAK_II	cd06648	1.7e-06	204	470
STKc_PAK2	cd06655	2.1e-05	204	561
STKc_TAO2	cd06634	1.3e-05	206	519
STKc_JNK3	cd07874	2.9e-12	206	596
STKc_TAO	cd06607	4.5e-05	207	582
STKc_JNK	cd07850	4.5e-19	207	571
STKc_p38alpha_MAPK14	cd07877	5.2e-11	207	567
STKc_p38delta_MAPK13	cd07879	5e-10	207	568
STKc_PAK	cd06614	1e-13	208	554
STKc_MAP4K4_6	cd06636	1.7e-05	208	476
STKc_p38gamma_MAPK12	cd07880	4.8e-12	208	568
STKc_CDK9	cd07865	1.4e-17	209	535
PKc_MKK7	cd06618	6.2e-07	210	503
STKc_STK10_LOK	cd06644	4.7e-06	210	494
STKc_p38	cd07851	3.4e-18	210	565
STKc_p38beta_MAPK11	cd07878	1.7e-12	210	576
PTKc_ALK_LTK	cd05036	0.0005	211	461
PTKc_Lyn	cd05072	0.00061	211	474
PTKc_Musk	cd05050	0.00048	212	455
STKc_SLK	cd06643	3.9e-06	212	492
PTKc_Itk	cd05112	0.00054	213	478
STKc_SLK_like	cd06611	3.3e-07	214	556
STKc_CDK10	cd07845	5.3e-16	214	544
PTKc_Frk_like	cd05068	9.6e-05	215	474
STKc_TNIK	cd06637	9.3e-07	215	476
STKc_MAPK4_6	cd07854	1.7e-11	215	567
STKc_CDK12	cd07864	3.5e-17	215	535
PTKc_Ror	cd05048	0.00075	216	455
PKc_MAPKK_Byr1_like	cd06620	6.3e-07	216	537
STKc_STK25-YSK1	cd06642	6.4e-06	216	486
PKc_MEK2	cd06649	0.00019	216	573
PKc_MEK1	cd06650	0.00039	216	577
STKc_MAPK15	cd07852	2.5e-18	216	584
STKc_ERK5	cd07855	7.1e-17	216	563
PTKc_Abl	cd05052	0.0006	217	475
PTKc_Jak2_Jak3_rpt2	cd05081	0.00079	217	488
STKc_MST4	cd06640	1.7e-05	217	497
STKc_MST3	cd06641	0.00012	217	486
STKc_ERK1_2_like	cd07849	3.9e-16	217	586
STKc_Sty1_Hog1	cd07856	1e-13	217	557
STKc_TEY_MAPK_plant	cd07858	7.8e-27	217	576
STKc_BUR1	cd07866	9.8e-16	217	535
STKc_MAP4K3_like	cd06613	4.3e-09	218	475
STKc_ASK	cd06624	2.1e-07	218	475
STKc_MST1_2	cd06612	1.3e-09	218	535
STKc_PCTAIRE_like	cd07844	4.9e-25	218	535
STKc_PFTAIRE2	cd07870	2.8e-09	218	535
PTKc_Btk_Bmx	cd05113	2.5e-05	219	476
PTKc_Tec_Rlk	cd05114	0.0006	219	472
STKc_myosinIII_like	cd06608	6.5e-09	219	476
STKc_MEKK2	cd06652	3e-05	219	468
STKc_MEKK3	cd06651	1.2e-07	219	477
STKc_MEKK3_like_1	cd06653	3e-06	219	476
STKc_CDC2L6	cd07867	3e-10	219	535
STKc_CDK8	cd07868	2.6e-09	219	535
STKc_PFTAIRE1	cd07869	7e-07	219	520
STKc_Nek6_Nek7	cd08224	1.7e-08	219	457
STKc_Nek6	cd08228	3.1e-06	219	476
PTKc_Jak_rpt2	cd05038	3.3e-05	220	453
STKc_ROCK_NDR_like	cd05573	1.5e-09	220	513
STKc_phototropin_lik	cd05574	3.5e-06	220	443
STKc_Sid2p_Dbf2p	cd05600	0.00029	220	532
STKc_MAST	cd05609	2.1e-07	220	532
STKc_PRKX_like	cd05612	4.5e-07	220	506
STKc_MST3_like	cd06609	1.4e-09	220	488
STKc_OSR1_SPAK	cd06610	2.5e-09	220	535
PKc_MEK	cd06615	9.2e-09	220	554
PKc_MKK4	cd06616	9.9e-08	220	500
PKc_MKK5	cd06619	0.00084	220	558
STKc_NAK1_like	cd06917	1.4e-07	220	478
STKc_CDKL	cd07833	1.9e-21	220	535
STKc_CDC2L1	cd07843	3.1e-17	220	535
STKc_CDKL2_3	cd07846	3.4e-20	220	535
STKc_CDKL5	cd07848	1e-22	220	535
STKc_CDK6	cd07862	1.1e-18	220	508
SPS1	COG0515	9.3e-48	220	601
PTKc_EGFR_like	cd05057	0.001	221	468
PKc_STE	cd05122	1.9e-16	221	534
STKc_Yank1	cd05578	1.1e-09	221	476
STKc_MSK_N	cd05583	2.4e-06	221	493
STKc_cPKC	cd05587	5.2e-07	221	538
STKc_LATS	cd05598	0.00078	221	553
STKc_GRK4_like	cd05605	4.1e-08	221	542
STKc_MSK1_N	cd05613	4.2e-05	221	509
STKc_MSK2_N	cd05614	4.8e-06	221	533
STKc_cPKC_alpha	cd05615	3.6e-06	221	536
STKc_cPKC_beta	cd05616	0.00015	221	515
STKc_GRK6	cd05630	1.1e-05	221	512
STKc_GRK4	cd05631	1.3e-05	221	506
STKc_GRK5	cd05632	2.1e-06	221	493
STKc_MAPKKK	cd06606	1.7e-19	221	535
STKc_MEKK4	cd06626	2.1e-11	221	535
STKc_MAPKKK_Byr2_lik	cd06628	2.4e-08	221	476
STKc_YSK4	cd06631	4.7e-07	221	476
STKc_Cdc7_like	cd06627	2.2e-13	221	535
STKc_CCRK	cd07832	9.3e-36	221	536
STKc_Pho85	cd07836	5.3e-35	221	535
STKc_CdkB_plant	cd07837	1.8e-17	221	536
STKc_CDK5	cd07839	1.1e-18	221	535
STKc_MAPK	cd07834	2e-23	221	583
STKc_CDK7	cd07841	5.9e-22	221	549
STKc_CDK8_like	cd07842	9.9e-16	221	535
STKc_CDKL1_4	cd07847	3.8e-37	221	535
STKc_NLK	cd07853	2.9e-12	221	599
STKc_MPK1	cd07857	2e-16	221	563
STKc_TDY_MAPK_plant	cd07859	3.9e-24	221	584
STKc_CDK2_3	cd07860	1.4e-30	221	535
STKc_CDK1_euk	cd07861	8.1e-36	221	535
STKc_CDK4	cd07863	2.4e-27	221	535
STKc_PCTAIRE3	cd07871	9.8e-11	221	535
STKc_PCTAIRE2	cd07872	2.2e-09	221	513
STKc_PCTAIRE1	cd07873	2.7e-09	221	520
STKc_Nek2	cd08217	3.2e-09	221	475
STKc_Nek1	cd08218	1.5e-05	221	476
STKc_Nek3	cd08219	1.7e-11	221	475
STKc_Nek8	cd08220	1.2e-06	221	476
STKc_Nek9	cd08221	9.2e-07	221	464
STKc_Nek4	cd08223	1.2e-05	221	475
STKc_Nek5	cd08225	0.00031	221	465
STKc_Nek7	cd08229	8.3e-07	221	479
STKc_Nek11	cd08222	6.7e-06	221	475
STKc_Nek	cd08215	1.4e-13	221	456
STKc_Nek10	cd08528	4.6e-05	221	472
STKc_FA2-like	cd08529	2e-07	221	443
STKc_CNK2-like	cd08530	4.1e-09	221	443
PTKc_Src_like	cd05034	0.00019	222	449
STKc_CMGC	cd05118	1.1e-54	222	535
STKc_PKA	cd05580	2.4e-08	222	499
STKc_PKN	cd05589	3.2e-07	222	514
STKc_DMPK_like	cd05597	0.00054	222	549
STKc_PDK1	cd05581	2.6e-13	222	464
STKc_NDR_like	cd05599	4.1e-05	222	504
STKc_CRIK	cd05601	0.00017	222	514
STKc_NDR2	cd05627	0.00095	222	554
STKc_NDR1	cd05628	0.00029	222	540
STKc_MAPKKK_Bck1_lik	cd06629	2.3e-08	222	475
STKc_CDK_like	cd07829	3.7e-39	222	535
STKc_MAK_like	cd07830	3.9e-25	222	535
STKc_MOK	cd07831	1.1e-21	222	535
STKc_CDK1_like	cd07835	2.1e-35	222	535
STKc_CDK4_6_like	cd07838	1.1e-19	222	535
STKc_CDK9_like	cd07840	4.7e-22	222	535
PKc_MAPKK	cd06605	1e-09	223	540
PKc_MKK3_6	cd06617	1.4e-07	223	461
PKc_MAPKK_Pek1_like	cd06621	5e-09	223	554
PKc_MAPKK_PBS2_like	cd06622	4e-06	223	503
PKc_MAPKK_plant_like	cd06623	1.7e-13	223	540
PTKc_Tec_like	cd05059	0.00067	224	439
STKc_RSK_N	cd05582	3.2e-05	225	541
STKc_p70S6K	cd05584	3.2e-06	225	552
PTKc	cd00192	5.3e-06	226	462
PTKc_Ack_like	cd05040	3.8e-06	226	458
PTKc_Fes_like	cd05041	0.00065	226	458
PTKc_Fer	cd05085	0.00042	226	475
STKc_PKC	cd05570	5.5e-07	226	514
STKc_PKB	cd05571	5.2e-07	226	553
STKc_SGK	cd05575	0.00016	226	514
STKc_aPKC	cd05588	2.1e-05	226	554
STKc_nPKC_eta	cd05590	3.1e-05	226	554
STKc_nPKC_epsilon	cd05591	3.7e-06	226	538
STKc_nPKC_theta_delt	cd05592	1.1e-07	226	537
STKc_PKB_gamma	cd05593	0.00019	226	552
STKc_PKB_beta	cd05595	0.00036	226	549
STKc_PKB_alpha	cd05594	2.2e-05	226	569
STKc_SGK1	cd05602	3.7e-05	226	568
STKc_SGK2	cd05603	7.7e-06	226	537
STKc_SGK3	cd05604	0.00078	226	542
STKc_aPKC_zeta	cd05617	1.7e-05	226	554
STKc_nPKC_theta	cd05619	5.8e-07	226	542
STKc_nPKC_delta	cd05620	0.00012	226	526
STKc_MEKK3_like	cd06625	9e-11	226	475
STKc_MEKK1	cd06630	7.3e-07	226	444
STKc_MEKK1_plant	cd06632	9.3e-09	226	535
STKc_GRK3	cd05633	6.7e-05	227	488
STKc_beta_ARK	cd05606	2.4e-06	227	510
PKc	cd00180	3.1e-69	228	533
STKc_AGC	cd05123	1.2e-12	228	455
STKc_cGK_PKG	cd05572	9.6e-11	228	460
STKc_GRK	cd05577	4e-07	228	492
STKc_YPK1_like	cd05585	5.7e-06	228	536
STKc_Sck1_like	cd05586	0.00045	228	595
STKc_GRK7	cd05607	4.3e-05	228	494
STKc_GRK1	cd05608	3.5e-07	228	511
STKc_MAST_like	cd05579	1.7e-10	228	454
Pkinase	pfam00069	5e-59	222	535
Pkinase_Tyr	pfam07714	1.9e-08	222	455
TyrKc	smart00219	2.8e-08	222	459
STYKc	smart00221	7.2e-87	222	535
S_TKc	smart00220	8.4e-94	232	535

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040462	Polymorphism	p.ARG451GLN	N/A
Swiss-Prot	VAR_040461	Polymorphism	p.ASN295SER	N/A
Swiss-Prot	VAR_040460	Polymorphism	p.HIS245ASN	N/A
Swiss-Prot	VAR_040463	Polymorphism	p.PHE455TYR	N/A
Swiss-Prot	VAR_040459	Polymorphism	p.PRO198LEU	N/A
Swiss-Prot	VAR_040458	Polymorphism	p.SER98GLY	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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