Results for the protein: P08183

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
COG1123	COG1123	1.5e-12	197	636
ABCC_SUR2	cd03288	6.7e-21	318	630
ABCC_CFTR1	cd03291	9.2e-08	358	655
ModF	COG1119	2.5e-13	370	612
TagH	COG1134	4.6e-08	372	633
ABCC_TAP	cd03248	7.4e-85	385	606
PstB	COG1117	7.4e-16	385	623
YhbG	COG1137	2.6e-10	385	625
Ttg2A	COG1127	4.6e-13	387	636
CcmA	COG1131	3.2e-38	388	715
ABCG_EPDR	cd03213	3.5e-14	389	610
ABCG_PDR_domain2	cd03232	3e-08	389	610
ABCG_PDR_domain1	cd03233	4.9e-08	389	610
ABCG_White	cd03234	1.6e-11	389	610
ABCC_NFT1	cd03369	7.9e-19	389	612
sufC	COG0396	1.3e-12	389	630
Uup	COG0488	1e-06	389	829
TauB	COG1116	2.3e-14	389	638
DppF	COG1124	5.1e-22	389	625
ZnuC	COG1121	5e-12	389	640
MglA	COG1129	4.7e-08	389	764
CbiO	COG1122	1.9e-39	389	637
ABCC_MRP_domain2	cd03244	2.9e-61	390	612
ABCC_bacteriocin_exp	cd03245	2.3e-68	390	610
ABCC_Glucan_exporter	cd03254	9e-117	390	620
ABCC_CFTR2	cd03289	1e-12	390	660
CysA	COG1118	1.3e-13	390	714
FepC	COG1120	2.8e-17	390	641
GlnQ	COG1126	2.6e-20	390	627
ABC_RNaseL_inhibitor	cd03236	0.00018	391	624
ABC_MetN_methionine_	cd03258	1.4e-20	391	620
ABC_NikE_OppD_transp	cd03257	3.2e-32	391	610
ABC_CysA_sulfate_imp	cd03296	1.3e-15	391	633
LivF	COG0410	8.5e-14	391	628
DppD	COG0444	3.4e-12	391	669
OpuBA	COG1125	2.5e-13	391	739
AbcC	COG1135	2.4e-16	391	675
SalX	COG1136	4.2e-32	391	613
ABC_Carb_Monos_I	cd03216	6.8e-20	392	609
ABC_FeS_Assembly	cd03217	2e-10	392	622
ABC_YhbG	cd03218	3.3e-09	392	620
ABC_Mj1267_LivG_bran	cd03219	5.1e-15	392	621
ABCF_EF-3	cd03221	1.4e-08	392	605
ABCD_peroxisomal_ALD	cd03223	4.8e-11	392	606
ABC_TM1139_LivF_bran	cd03224	2.9e-16	392	618
ABC_Class3	cd03229	1.5e-44	392	605
ABC_DR_subfamily_A	cd03230	1.1e-38	392	606
ABCC_MRP_Like	cd03228	6.3e-123	392	605
ABCC_Protease_Secret	cd03246	3.4e-61	392	606
ABCC_cytochrome_bd	cd03247	9.7e-56	392	610
ABCC_MsbA	cd03251	1.3e-127	392	626
ABCC_MRP_domain1	cd03250	8.3e-19	392	605
ABCC_ATM1_transporte	cd03253	2.2e-113	392	629
ABC_MJ0796_LolCDE_Ft	cd03255	1.9e-27	392	606
ABC_PhnC_transporter	cd03256	8.6e-17	392	622
ABC_Carb_Solutes_lik	cd03259	1.6e-26	392	610
ABC_Org_Solvent_Resi	cd03261	1.4e-17	392	621
ABC_drug_resistance_	cd03264	2.1e-11	392	610
ABC_subfamily_A	cd03263	1.7e-13	392	616
ABC_HisP_GlnQ	cd03262	1e-20	392	606
ABCC_Hemolysin	cd03252	8.3e-103	392	629
ABC_NatA_sodium_expo	cd03266	3.2e-11	392	610
ABC_NatA_like	cd03267	9.3e-08	392	603
ABC_BcrA_bacitracin_	cd03268	9.8e-11	392	610
ABC_PstB_phosphate_t	cd03260	1.4e-38	392	615
ABC_MTABC3_MDL1_MDL2	cd03249	1.3e-177	392	629
ABCC_SUR1_N	cd03290	2e-15	392	605
ABC_FtsE_transporter	cd03292	1.5e-17	392	597
ABC_NrtD_SsuB_transp	cd03293	2.4e-20	392	605
ABC_Pro_Gly_Betaine	cd03294	4.7e-17	392	626
ABC_OpuCA_Osmoprotec	cd03295	1.9e-15	392	621
ABC_ThiQ_thiamine_tr	cd03298	3.9e-10	392	610
ABC_ModC_like	cd03299	8.9e-14	392	626
ABC_MalK_N	cd03301	2.6e-13	392	610
ABC_ATPase	cd00267	1.9e-65	393	605
ABC_Iron-Siderophore	cd03214	3.9e-20	393	610
ABC_cobalt_CbiO_doma	cd03225	5.9e-45	393	605
ABC_cobalt_CbiO_doma	cd03226	6.6e-15	393	607
ABC_Metallic_Cations	cd03235	4.8e-13	393	609
ABC_RNaseL_inhibitor	cd03237	0.00018	401	620
ABC_UvrA_II	cd03271	1e-05	405	612
ABC_DrrA	cd03265	1.2e-12	406	616
ABC_ModC_molybdenum_	cd03297	7.2e-12	408	610
MdlB	COG1132	2.3e-171	694	1277
ABCC_SUR2	cd03288	2.7e-27	964	1277
ABCC_CFTR1	cd03291	9.7e-07	995	1280
ModF	COG1119	1.1e-12	997	1257
ABCC_TAP	cd03248	2e-100	1026	1251
CcmA	COG1131	8.5e-21	1027	1280
PstB	COG1117	1.7e-13	1028	1276
Ttg2A	COG1127	1.1e-12	1028	1280
ABC_putative_ATPase	cd03269	3.4e-10	1031	1255
ABCG_EPDR	cd03213	7.7e-13	1032	1255
ABCG_White	cd03234	1.8e-09	1032	1255
TauB	COG1116	8.7e-13	1032	1277
DppF	COG1124	5.7e-17	1032	1270
CbiO	COG1122	5.7e-37	1032	1269
ABCC_MRP_domain2	cd03244	5.3e-58	1033	1257
ABCC_bacteriocin_exp	cd03245	5.3e-63	1033	1255
ABCC_Glucan_exporter	cd03254	8.2e-116	1033	1265
ABCC_CFTR2	cd03289	1.3e-07	1033	1280
FepC	COG1120	1.9e-13	1033	1276
GlnQ	COG1126	3.9e-16	1033	1272
ABC_MetN_methionine_	cd03258	1e-18	1034	1265
ABC_NikE_OppD_transp	cd03257	2.1e-25	1034	1255
ABC_CysA_sulfate_imp	cd03296	6.1e-21	1034	1275
PhnK	COG1101	1.4e-09	1034	1262
SalX	COG1136	5.6e-27	1034	1257
ABCF_EF-3	cd03221	9.2e-09	1035	1250
ABC_RNaseL_inhibitor	cd03222	0.00011	1035	1269
ABCD_peroxisomal_ALD	cd03223	2.4e-11	1035	1251
ABC_KpsT_Wzt	cd03220	3.2e-11	1035	1255
ABC_Class3	cd03229	6.9e-41	1035	1250
ABC_DR_subfamily_A	cd03230	1.1e-28	1035	1251
ABCC_MRP_Like	cd03228	1.6e-113	1035	1250
ABCC_cytochrome_bd	cd03247	7.3e-58	1035	1255
ABCC_MsbA	cd03251	4.9e-121	1035	1271
ABCC_MRP_domain1	cd03250	3.1e-18	1035	1250
ABCC_ATM1_transporte	cd03253	9.9e-108	1035	1274
ABC_MJ0796_LolCDE_Ft	cd03255	2.7e-16	1035	1251
ABC_Carb_Solutes_lik	cd03259	1.5e-24	1035	1255
ABC_Org_Solvent_Resi	cd03261	6.2e-16	1035	1266
ABC_subfamily_A	cd03263	1.2e-12	1035	1261
ABC_HisP_GlnQ	cd03262	1.3e-17	1035	1251
ABCC_Hemolysin	cd03252	2e-95	1035	1274
ABC_PstB_phosphate_t	cd03260	1.8e-35	1035	1260
ABC_MTABC3_MDL1_MDL2	cd03249	5e-178	1035	1274
ABCC_SUR1_N	cd03290	3.3e-14	1035	1250
ABC_FtsE_transporter	cd03292	1e-15	1035	1251
ABC_NrtD_SsuB_transp	cd03293	4.4e-20	1035	1259
ABC_OpuCA_Osmoprotec	cd03295	1.2e-14	1035	1279
ABC_ThiQ_thiamine_tr	cd03298	5.8e-11	1035	1255
ABC_PotA_N	cd03300	7.1e-16	1035	1260
ABC_MalK_N	cd03301	7.8e-13	1035	1255
ABC_ATPase	cd00267	1.7e-59	1036	1250
ABC_Iron-Siderophore	cd03214	4.5e-14	1036	1255
ABC_cobalt_CbiO_doma	cd03225	6.4e-38	1036	1250
ABC_cobalt_CbiO_doma	cd03226	3.6e-17	1036	1252
ABC_Metallic_Cations	cd03235	8.1e-13	1036	1255
ABCC_NFT1	cd03369	2.3e-23	1036	1257
ABC_Carb_Monos_II	cd03215	3.7e-12	1038	1251
ABC_CcmA_heme_export	cd03231	3.5e-08	1039	1252
ABCC_Protease_Secret	cd03246	5.4e-64	1040	1251
ABC_UvrA	cd03238	2.9e-05	1045	1255
ABC_ModC_like	cd03299	4e-14	1047	1266
ABC_Carb_Monos_I	cd03216	1.3e-17	1048	1254
LivG	COG0411	8.7e-13	1048	1256
ABC_ModC_molybdenum_	cd03297	1.3e-12	1049	1255
SunT	COG2274	2.1e-77	12	630
COG4178	COG4178	0.00021	18	619
ABC_membrane	pfam00664	1.8e-93	51	348
CydD	COG4988	2.6e-34	63	634
CydC	COG4987	7.1e-13	105	629
ATM1	COG5265	1.9e-74	147	628
COG4172	COG4172	3.4e-08	206	635
COG4586	COG4586	3.9e-07	366	708
PhnK	COG4107	3.5e-05	386	633
HisP	COG4598	1.5e-17	386	631
PotA	COG3842	1.8e-14	387	702
COG4181	COG4181	1.7e-12	387	610
COG3845	COG3845	1.8e-05	388	798
ProV	COG4175	7.3e-09	388	692
PhnL	COG4778	7.3e-09	388	600
COG3638	COG3638	5.8e-15	389	644
MalK	COG3839	6.1e-15	389	703
CcmA	COG4133	9.3e-08	390	606
COG4152	COG4152	7.3e-06	390	678
FtsE	COG2884	3.9e-14	391	614
ThiQ	COG3840	7.1e-11	391	629
ArtP	COG4161	2.4e-19	391	629
AppF	COG4608	1.1e-15	391	657
NatA	COG4555	6.2e-15	392	635
CeuD	COG4604	2e-07	392	624
COG4619	COG4619	5.4e-16	392	620
ModC	COG4148	2.2e-06	406	699
ABC_tran	pfam00005	1.7e-39	434	559
SunT	COG2274	2.8e-64	633	1275
ArpD	COG4618	2.5e-17	676	1278
PvdE	COG4615	3.7e-09	701	1265
CydC	COG4987	9.3e-13	701	1274
CydD	COG4988	4.1e-30	710	1280
ABC_membrane	pfam00664	5.8e-85	715	991
ATM1	COG5265	4.1e-72	772	1273
SapF	COG4167	5.2e-08	1027	1280
TauB	COG4525	6.2e-12	1027	1279
HisP	COG4598	1.1e-13	1029	1274
PhnK	COG4107	1.3e-05	1031	1279
COG4136	COG4136	8.2e-08	1033	1260
FtsE	COG2884	1.7e-13	1034	1259
ThiQ	COG3840	3.1e-12	1034	1274
ArtP	COG4161	1.2e-13	1034	1274
NatA	COG4555	7.1e-15	1035	1279
COG4619	COG4619	3e-15	1035	1262
COG4674	COG4674	2.4e-06	1046	1259
BtuD	COG4138	1.1e-05	1049	1280
COG4559	COG4559	5.7e-07	1052	1280
ABC_tran	pfam00005	2.3e-36	1077	1204
AAA	smart00382	1.1e-39	419	611
AAA	smart00382	2.9e-34	1062	1250

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_055424	Polymorphism	p.ALA80GLU	N/A
Swiss-Prot	VAR_055426	Polymorphism	p.ALA599THR	N/A
Swiss-Prot	VAR_015004	Polymorphism	p.ALA999THR	N/A
Swiss-Prot	VAR_022278	Polymorphism	p.ARG593CYS	N/A
Swiss-Prot	VAR_055427	Polymorphism	p.ARG669CYS	N/A
dbSNP	rs9282564	Polymorphism	p.ASN21ASP	N/A
Swiss-Prot	VAR_055423	Polymorphism	p.ASN44SER	N/A
Swiss-Prot	VAR_015005	Polymorphism	p.GLN1107PRO	N/A
Swiss-Prot	VAR_018351	Polymorphism	p.GLU108LYS	N/A
Swiss-Prot	VAR_022277	Polymorphism	p.GLU566LYS	N/A
Swiss-Prot	VAR_015002	Polymorphism	p.GLY185VAL	N/A
Swiss-Prot	VAR_055425	Polymorphism	p.ILE261VAL	N/A
Swiss-Prot	VAR_055429	Polymorphism	p.ILE829VAL	N/A
Swiss-Prot	VAR_022279	Polymorphism	p.ILE836VAL	N/A
Swiss-Prot	VAR_035737	Polymorphism	p.LYS887ASN	N/A
Swiss-Prot	VAR_018352	Polymorphism	p.MET986VAL	N/A
Swiss-Prot	VAR_015001	Polymorphism	p.PHE103LEU	N/A
Swiss-Prot	VAR_022276	Polymorphism	p.PHE17LEU	N/A
Swiss-Prot	VAR_022280	Polymorphism	p.PRO1051ALA	N/A
dbSNP	rs2032582	Polymorphism	p.SER893ALA	N/A
Swiss-Prot	VAR_015003	Polymorphism	p.SER400ASN	N/A
dbSNP	rs2229109	Polymorphism	p.SER400ILE	N/A
dbSNP	rs2229107	Polymorphism	p.SER1141THR	N/A
Swiss-Prot	VAR_013362	Polymorphism	p.SER893THR	N/A
Swiss-Prot	VAR_018353	Polymorphism	p.VAL1251ILE	N/A
Swiss-Prot	VAR_055428	Polymorphism	p.VAL801MET	N/A
OMIM	171050.0001	Disease	p.GLY185VAL	COLCHICINE RESISTANCE

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258