Results for the protein: P29474

Results for the Protein: P29474

266648

4846

NOS3

NCBI, UniProt

NOS3_HUMAN RecName: Full=Nitric oxide synthase, endothelial; AltName: Full=Constitutive NOS; Short=cNOS; AltName: Full=EC-NOS; AltName: Full=Endothelial NOS; Short=eNOS; AltName: Full=NOS type III; Short=NOSIII

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Swiss-Prot Protein: P29474

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
NOS_oxygenase	cd00575	9.2e-292	122	477
NOS_oxygenase_prok	cd00794	1.3e-164	122	477
CysJ	COG0369	3.2e-90	464	1160
CYPOR	cd06204	3.2e-74	754	1160
CYPOR_like	cd06182	1.4e-130	762	1160
SiR	cd06199	2.9e-49	762	1160
Nitric_oxide_synthas	cd06202	3.1e-236	762	1164
bifunctional_CYPOR	cd06206	3.1e-51	762	1160
CyPoR_like	cd06207	8.8e-66	762	1160
FNR_like	cd00322	4.4e-66	764	1158
methionine_synthase_	cd06203	6.1e-68	765	1160
SiR_like2	cd06201	4.9e-12	824	1160
flavohem_like_fad_na	cd06184	7.5e-05	898	1138
SiR_like1	cd06200	2.8e-14	905	1160
FNR_iron_sulfur_bind	cd06217	0.00015	905	1136
FNR_iron_sulfur_bind	cd06191	0.001	909	1160
CYPOR_like_FNR	cd06208	1.9e-09	909	1160
FNR1	cd06195	4.1e-05	910	1142
O2ase_reductase_like	cd06187	0.00098	912	1142
FNR_like_3	cd06198	0.00018	912	1143
cyt_b5_reduct_like	cd06183	0.00098	912	1148
NO_synthase	pfam02898	7.7e-295	115	481
COG4362	COG4362	1.5e-147	117	485
Flavodoxin_1	pfam00258	4.3e-67	522	698
FAD_binding_1	pfam00667	9.4e-120	752	979
NAD_binding_1	pfam00175	9e-23	1011	1125

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_036303	Polymorphism	p.ARG474CYS	N/A
Swiss-Prot	VAR_031218	Polymorphism	p.ARG112GLN	N/A
Swiss-Prot	VAR_036304	Polymorphism	p.ARG602GLN	N/A
Swiss-Prot	VAR_061377	Polymorphism	p.ARG665HIS	N/A
Swiss-Prot	VAR_031220	Polymorphism	p.ARG885MET	N/A
Swiss-Prot	VAR_031221	Polymorphism	p.GLN982LEU	N/A
Swiss-Prot	VAR_008037	Polymorphism	p.GLU298ASP	N/A
Swiss-Prot	VAR_031219	Polymorphism	p.VAL827MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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