Results for the protein: Q12774

Results for the Protein: Q12774

290457679

7984

ARHGEF5

NCBI, UniProt

ARHG5_HUMAN RecName: Full=Rho guanine nucleotide exchange factor 5; AltName: Full=Ephexin-3; AltName: Full=Guanine nucleotide regulatory protein TIM; AltName: Full=Oncogene TIM; AltName: Full=Transforming immortalized mammary oncogene; AltName: Full=p60 TIM

			0 4 0 4 0

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

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Default View: RhoGEF - cd00160 RhoGEF - smart00325 RhoGEF - pfam00621 PH_ephexin - cd01221 PH - smart00233 PH - pfam00169 PH - cd00821 SH3 - smart00326 SH3 - cd00174 SH3_2 - pfam07653 SH3_1 - pfam00018	Swiss-Prot Protein: Q12774 Identical to: NP_005426 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PH_ephexin	cd01221	5.3e-71	1389	1504
PH	cd00821	0.00011	1393	1500
SH3	cd00174	3.8e-15	1514	1568
RhoGEF	pfam00621	1e-53	1179	1357
PH	pfam00169	8.4e-08	1391	1502
SH3_1	pfam00018	3e-08	1516	1563
RhoGEF	smart00325	1.8e-55	1178	1357
PH	smart00233	1.5e-06	1391	1502
SH3	smart00326	1.1e-15	1511	1569
SH3_2	pfam07653	4.1e-06	1514	1568

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs141058548	Polymorphism	p.ASP175GLY	N/A
dbSNP	rs61734507	Polymorphism	p.PHE1568LEU	N/A
dbSNP	rs200205335	Polymorphism	p.SER372ILE	N/A
dbSNP	rs145771593	Polymorphism	p.THR347ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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