Results for the protein: Q5S007

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Rab35	cd04110	0.00079	1331	1538
Rab2	cd01866	0.0003	1332	1507
Rab8_Rab10_Rab13_lik	cd01867	0.0001	1332	1507
Rab30	cd04114	9.4e-07	1332	1509
Rab3	cd01865	2.1e-06	1334	1508
RhoA_like	cd01870	0.00014	1334	1517
Rac1_like	cd01871	0.00019	1334	1512
Rab33B_Rab33A	cd04115	0.0007	1334	1515
Rab	cd00154	1.1e-08	1335	1506
Ran	cd00877	3.5e-05	1335	1511
Rab7	cd01862	0.00012	1335	1510
Rab18	cd01863	0.00044	1335	1500
Rab1_Ypt1	cd01869	0.00032	1335	1507
Rab6	cd01861	0.00042	1335	1508
Rab4	cd04113	9.2e-07	1335	1534
Rab26	cd04112	0.00065	1335	1511
Rab15	cd04117	0.00024	1335	1501
Rab14	cd04122	0.00059	1335	1507
Rab27A	cd04127	8e-05	1335	1508
Ras_like_GTPase	cd00882	5e-22	1339	1506
PTKc_PDGFR_alpha	cd05105	0.00024	1730	2138
STKc_TAO1	cd06635	0.00011	1851	2168
STKc_PAK6	cd06659	8.2e-06	1855	2154
PTKc_FGFR1	cd05098	1.2e-05	1856	2145
STKc_PAK_I	cd06647	0.00071	1857	2152
STKc_myosinIIIB	cd06639	0.001	1859	2135
PTKc_PDGFR	cd05055	5.6e-05	1860	2136
STKc_myosinIIIA	cd06638	0.00029	1861	2137
PTKc_DDR2	cd05095	5e-05	1863	2134
PTKc_FGFR2	cd05101	7.2e-06	1863	2143
STKc_p38alpha_MAPK14	cd07877	0.00067	1863	2183
STKc_JNK	cd07850	0.00012	1864	2197
STKc_p38gamma_MAPK12	cd07880	0.00028	1864	2204
STKc_PAK	cd06614	2.6e-11	1865	2144
PTKc_EGFR_like	cd05057	4e-08	1867	2148
PTKc_TrkA	cd05092	0.00013	1867	2142
PTK_HER3	cd05111	3.4e-07	1867	2136
PKc_MKK7	cd06618	5e-07	1867	2143
STKc_MAP4K5	cd06646	1.2e-05	1867	2133
STKc_MAP4K3	cd06645	1.7e-05	1867	2133
STKc_p38	cd07851	9e-07	1867	2199
STKc_p38beta_MAPK11	cd07878	0.00053	1867	2199
PTKc_FAK	cd05056	5.3e-09	1868	2140
PTKc_Csk_like	cd05039	1.4e-11	1868	2135
PTKc_Csk	cd05082	1e-08	1868	2135
PTKc_Chk	cd05083	5.7e-18	1868	2135
PTKc_Trk	cd05049	2.3e-08	1869	2134
PTKc_EphR_A10	cd05064	3.5e-06	1869	2136
PTKc_Tie2	cd05088	2.6e-09	1869	2154
PTKc_FGFR4	cd05099	4.5e-07	1869	2148
PTKc_FGFR3	cd05100	0.00012	1869	2175
PTKc_HER2	cd05109	1.4e-05	1869	2148
PTKc_HER4	cd05110	7.4e-06	1869	2155
PTKc_EGFR	cd05108	5.6e-05	1869	2171
STKc_CDK12	cd07864	2.3e-05	1869	2169
PTKc_InsR_like	cd05032	2e-08	1870	2134
PTKc_EphR	cd05033	1.1e-08	1870	2136
PTKc_Tec_like	cd05059	1.6e-09	1870	2133
PTKc_Frk_like	cd05068	3.4e-16	1870	2135
PTKc_Lck_Blk	cd05067	4.4e-07	1870	2135
PTKc_EphR_A	cd05066	3.1e-05	1870	2136
PTKc_Musk	cd05050	1.2e-06	1870	2134
PTKc_Jak2_Jak3_rpt2	cd05081	2.9e-08	1870	2136
PTKc_FGFR	cd05053	2.9e-08	1870	2137
PTKc_Tec_Rlk	cd05114	1.3e-08	1870	2133
PTKc_Btk_Bmx	cd05113	6.7e-09	1870	2133
PTKc_Itk	cd05112	3.1e-10	1870	2133
STKc_TAO	cd06607	9.9e-06	1870	2169
PKc_MAPKK_Byr1_like	cd06620	5.6e-07	1870	2135
STKc_TNIK	cd06637	4.8e-05	1870	2131
STKc_Nek6_Nek7	cd08224	2.8e-08	1870	2140
STKc_ASK	cd06624	4.6e-07	1871	2137
STKc_SLK	cd06643	1.5e-06	1871	2143
STKc_TAO2	cd06634	7e-06	1871	2183
STKc_STK10_LOK	cd06644	1.1e-05	1872	2152
PTKc_Tie1	cd05089	2.3e-08	1873	2156
STKc_PKA	cd05580	1.6e-08	1873	2132
STKc_PDK1	cd05581	3.2e-10	1873	2137
PKc_MAPKK	cd06605	8.3e-08	1873	2136
STKc_MAP4K3_like	cd06613	3.9e-09	1873	2129
PKc_MKK3_6	cd06617	2.4e-06	1873	2146
PKc_MKK5	cd06619	0.00084	1873	2149
PKc_MAPKK_PBS2_like	cd06622	4.1e-06	1873	2192
STKc_PAK_II	cd06648	1.6e-05	1873	2144
STKc_ERK5	cd07855	9.1e-07	1873	2158
STKc_CDK9	cd07865	1.1e-05	1873	2129
PTK_CCK4	cd05046	0.00033	1874	2134
PTKc_EphR_A2	cd05063	1.9e-05	1874	2138
PTKc_EphR_B	cd05065	1.3e-05	1874	2136
PTKc_Src	cd05071	1.8e-07	1874	2137
PTKc_Ror1	cd05090	2.9e-05	1874	2135
PTKc_VEGFR3	cd05102	0.00089	1874	2141
PTKc_VEGFR2	cd05103	0.00031	1874	2141
PTKc_Ror2	cd05091	0.00028	1874	2135
PTKc_Srm_Brk	cd05148	1.5e-12	1874	2135
STKc_TEY_MAPK_plant	cd07858	5.4e-05	1874	2208
PTKc_Jak_rpt2	cd05038	1.3e-10	1875	2136
PTKc_Ror	cd05048	1.5e-05	1875	2135
PTKc_Abl	cd05052	1.3e-09	1875	2136
STKc_phototropin_lik	cd05574	0.0001	1875	2115
STKc_MAST	cd05609	0.00075	1875	2194
STKc_PRKX_like	cd05612	1.7e-05	1875	2138
STKc_MST3_like	cd06609	2.2e-09	1875	2148
PKc_MEK	cd06615	2.7e-05	1875	2142
PKc_MAPKK_plant_like	cd06623	9.6e-13	1875	2137
STKc_CDK8	cd07868	0.00012	1875	2134
STKc_CDC2L6	cd07867	5.2e-05	1875	2155
PKc_STE	cd05122	1.5e-12	1876	2129
STKc_GRK4_like	cd05605	9e-05	1876	2176
STKc_GRK6	cd05630	0.00066	1876	2149
STKc_MAPKKK	cd06606	9.3e-16	1876	2128
STKc_MEKK3	cd06651	3.2e-06	1876	2128
STKc_Pho85	cd07836	0.00041	1876	2163
STKc_CDK7	cd07841	7e-09	1876	2147
STKc_CDK10	cd07845	1.8e-07	1876	2150
STKc_MPK1	cd07857	1e-05	1876	2154
STKc_CDK2_3	cd07860	0.00041	1876	2163
STKc_CDKL1_4	cd07847	1.1e-06	1876	2163
STKc_Nek8	cd08220	4.1e-07	1876	2138
STKc_Nek5	cd08225	5.2e-05	1876	2137
STKc_FA2-like	cd08529	1.3e-09	1876	2136
PTKc_Src_like	cd05034	1.6e-13	1877	2135
PTKc_ALK_LTK	cd05036	5.3e-11	1877	2134
PTKc_Lyn	cd05072	2.5e-08	1877	2135
PTKc_Hck	cd05073	4.4e-09	1877	2135
PTKc_Yes	cd05069	6e-09	1877	2135
PTKc_InsR	cd05061	1.3e-06	1877	2140
PTKc_IGF-1R	cd05062	2.3e-06	1877	2134
PTKc_Jak1_rpt2	cd05079	6.3e-05	1877	2138
PTKc_Fyn_Yrk	cd05070	1.8e-07	1877	2135
STKc_myosinIII_like	cd06608	1.5e-06	1877	2131
PKc_MKK4	cd06616	8.5e-05	1877	2145
STKc_CDK1_like	cd07835	0.0003	1877	2163
STKc_CDK4_6_like	cd07838	5.2e-06	1877	2129
STKc_CDK9_like	cd07840	1.9e-07	1877	2129
STKc_MAPK4_6	cd07854	1.9e-05	1877	2149
STKc_PCTAIRE_like	cd07844	0.00071	1877	2163
STKc_Sty1_Hog1	cd07856	3.1e-06	1877	2149
STKc_PFTAIRE2	cd07870	0.00017	1877	2162
STKc_ERK1_2_like	cd07849	5.8e-06	1877	2152
STKc_BUR1	cd07866	5.8e-05	1877	2129
SPS1	COG0515	8.8e-33	1877	2302
STKc_cPKC_alpha	cd05615	0.00022	1878	2191
STKc_MAPKKK_Byr2_lik	cd06628	1.4e-06	1878	2134
STKc_NLK	cd07853	9.6e-08	1878	2237
STKc_TDY_MAPK_plant	cd07859	0.00017	1878	2176
STKc_CDK4	cd07863	0.00014	1878	2162
STKc_CDKL2_3	cd07846	2.9e-07	1878	2129
STKc_Nek1	cd08218	7.1e-05	1878	2137
STKc_Nek3	cd08219	5.6e-07	1878	2137
STKc_Nek7	cd08229	2.3e-07	1878	2137
STKc_Nek6	cd08228	2e-05	1878	2137
STKc_Nek10	cd08528	1.2e-05	1878	2134
PTK_Ryk	cd05043	5.1e-07	1879	2137
STKc_OSR1_SPAK	cd06610	9.1e-10	1879	2129
STKc_CdkB_plant	cd07837	1.7e-06	1879	2164
STKc_CDKL	cd07833	4.2e-07	1879	2129
STKc_STK25-YSK1	cd06642	7.5e-06	1880	2148
STKc_MST3	cd06641	3.7e-05	1880	2151
STKc_MST4	cd06640	0.00029	1880	2151
STKc_MST1_2	cd06612	2.7e-10	1881	2131
PKc_MAPKK_Pek1_like	cd06621	4.9e-05	1881	2140
STKc_MEKK3_like_1	cd06653	2.2e-05	1881	2134
PTKc_RET	cd05045	1.4e-05	1882	2134
STKc_Yank1	cd05578	6.4e-08	1882	2137
STKc_MSK_N	cd05583	0.00062	1882	2147
STKc_p70S6K	cd05584	0.00024	1882	2196
STKc_cPKC	cd05587	2.1e-05	1882	2196
STKc_PKN	cd05589	8.3e-07	1882	2190
STKc_cPKC_beta	cd05616	6.4e-05	1882	2193
STKc_MEKK4	cd06626	3e-10	1882	2128
STKc_Cdc7_like	cd06627	1.5e-10	1882	2128
STKc_Nek11	cd08222	0.00058	1882	2134
STKc_Nek4	cd08223	1.9e-06	1882	2137
STKc_CNK2-like	cd08530	9.5e-11	1882	2137
PTKc	cd00192	1.3e-14	1883	2133
PTKc_c-ros	cd05044	2.7e-08	1883	2134
PTKc_Ack_like	cd05040	1.7e-11	1883	2134
PTKc_Fes_like	cd05041	2.6e-13	1883	2134
PTKc_Tyk2_rpt2	cd05080	6e-08	1883	2137
PTKc_Zap-70	cd05115	7.8e-07	1883	2137
STKc_PKC	cd05570	1e-08	1883	2132
STKc_CDK8_like	cd07842	0.00021	1883	2129
PTKc_Axl_like	cd05035	7.7e-05	1884	2136
PTKc_Tie	cd05047	1.7e-08	1884	2137
PTKc_Met_Ron	cd05058	1.2e-05	1884	2138
PTKc_Tyro3	cd05074	6.3e-05	1884	2136
PTKc_Fer	cd05085	5.2e-08	1884	2134
STKc_PKB	cd05571	1.5e-05	1884	2171
STKc_RSK_N	cd05582	0.00047	1884	2182
STKc_aPKC	cd05588	0.00012	1884	2195
STKc_nPKC_eta	cd05590	0.00036	1884	2201
STKc_nPKC_theta_delt	cd05592	2e-05	1884	2194
STKc_PKB_gamma	cd05593	0.00016	1884	2177
STKc_PKB_alpha	cd05594	0.00012	1884	2195
STKc_PKB_beta	cd05595	0.00039	1884	2202
STKc_nPKC_epsilon	cd05591	5.8e-05	1884	2193
STKc_SGK	cd05575	9.7e-05	1884	2205
STKc_SGK2	cd05603	2.4e-05	1884	2206
STKc_beta_ARK	cd05606	1.6e-06	1884	2148
STKc_SGK1	cd05602	0.00055	1884	2197
STKc_nPKC_theta	cd05619	4.5e-06	1884	2170
STKc_GRK3	cd05633	0.00014	1884	2149
STKc_MEKK3_like	cd06625	4.7e-12	1884	2134
STKc_MEKK1	cd06630	1.2e-06	1884	2130
STKc_YSK4	cd06631	3e-07	1884	2132
STKc_MEKK1_plant	cd06632	2.8e-09	1884	2128
STKc_MEKK2	cd06652	0.00053	1884	2117
STKc_MAPKKK_Bck1_lik	cd06629	2.8e-06	1884	2130
STKc_NAK1_like	cd06917	4.1e-07	1884	2145
STKc_CDK_like	cd07829	3.4e-09	1884	2129
STKc_MAPK	cd07834	7.1e-08	1884	2158
STKc_Nek2	cd08217	1e-07	1884	2137
STKc_Nek9	cd08221	2e-08	1884	2134
STKc_Nek	cd08215	2.2e-12	1884	2134
PKc	cd00180	2e-53	1885	2132
PTKc_Aatyk	cd05042	2.5e-05	1885	2134
PTK_Jak_rpt1	cd05037	5.3e-05	1885	2133
PTKc_Syk_like	cd05060	1.8e-09	1885	2138
PTK_Jak2_Jak3_rpt1	cd05078	2.8e-06	1885	2133
PTKc_Fes	cd05084	2e-07	1885	2134
PTKc_Syk	cd05116	8.2e-08	1885	2137
STKc_AGC	cd05123	2.2e-11	1885	2129
STKc_CMGC	cd05118	4.4e-10	1885	2129
STKc_cGK_PKG	cd05572	2.3e-07	1885	2136
STKc_GRK	cd05577	3.2e-06	1885	2118
STKc_MAST_like	cd05579	1.2e-08	1885	2130
STKc_YPK1_like	cd05585	0.00023	1885	2168
STKc_GRK7	cd05607	0.00017	1885	2148
STKc_GRK1	cd05608	2.9e-06	1885	2158
STKc_SLK_like	cd06611	3.1e-06	1885	2140
STKc_MOK	cd07831	4.9e-05	1885	2129
STKc_MAK_like	cd07830	1.6e-08	1885	2129
STKc_CCRK	cd07832	8.6e-08	1885	2138
STKc_CDK5	cd07839	5e-05	1885	2163
STKc_MAPK15	cd07852	4.5e-06	1885	2167
STKc_CDC2L1	cd07843	1.6e-05	1887	2129
COG4886	COG4886	0.00067	938	1359
Ras	pfam00071	7e-06	1336	1502
Pkinase	pfam00069	5.8e-35	1879	2132
RAB	smart00175	3.3e-05	1335	1504
Miro	pfam08477	3.2e-39	1336	1455
Pkinase_Tyr	pfam07714	2.1e-19	1875	2132
TyrKc	smart00219	3.6e-20	1875	2132
STYKc	smart00221	1.2e-35	1875	2134
S_TKc	smart00220	7.2e-34	1889	2140

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_033903	Polymorphism	p.ALA419VAL	N/A
Swiss-Prot	VAR_054742	Polymorphism	p.ALA716VAL	N/A
Swiss-Prot	VAR_024945	Polymorphism	p.ARG1441CYS	N/A
Swiss-Prot	VAR_024938	Disease	p.ARG1067GLN	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024948	Disease	p.ARG1514GLN	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_040678	Polymorphism	p.ARG1550GLN	N/A
Swiss-Prot	VAR_024946	Disease	p.ARG1441GLY	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024944	Polymorphism	p.ARG1398HIS	N/A
Swiss-Prot	VAR_024947	Disease	p.ARG1441HIS	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_054744	Disease	p.ARG1728HIS	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024956	Disease	p.ARG1941HIS	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_054748	Disease	p.ARG2143HIS	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024931	Polymorphism	p.ARG50HIS	N/A
Swiss-Prot	VAR_054745	Disease	p.ARG1728LEU	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024935	Polymorphism	p.ARG793MET	N/A
Swiss-Prot	VAR_024951	Polymorphism	p.ARG1628PRO	N/A
Swiss-Prot	VAR_040679	Polymorphism	p.ARG1723PRO	N/A
Swiss-Prot	VAR_024960	Polymorphism	p.ASN2081ASP	N/A
Swiss-Prot	VAR_024962	Polymorphism	p.ASN2261ILE	N/A
Swiss-Prot	VAR_024933	Polymorphism	p.ASN551LYS	N/A
Swiss-Prot	VAR_047022	Polymorphism	p.ASP1375GLU	N/A
Swiss-Prot	VAR_024937	Polymorphism	p.ASP944TYR	N/A
Swiss-Prot	VAR_054740	Polymorphism	p.CYS228SER	N/A
Swiss-Prot	VAR_024936	Polymorphism	p.GLN930ARG	N/A
Swiss-Prot	VAR_054749	Polymorphism	p.GLU2395LYS	N/A
Swiss-Prot	VAR_024964	Polymorphism	p.GLY2385ARG	N/A
Swiss-Prot	VAR_024958	Disease	p.GLY2019SER	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024957	Disease	p.ILE2012THR	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024959	Disease	p.ILE2020THR	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024940	Disease	p.ILE1122VAL	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024943	Polymorphism	p.ILE1371VAL	N/A
Swiss-Prot	VAR_024934	Polymorphism	p.ILE723VAL	N/A
Swiss-Prot	VAR_054750	Disease	p.LEU2466HIS	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_054746	Polymorphism	p.LEU1870PHE	N/A
Swiss-Prot	VAR_024932	Polymorphism	p.LEU119PRO	N/A
Swiss-Prot	VAR_054743	Polymorphism	p.LYS871GLU	N/A
Swiss-Prot	VAR_064728	Polymorphism	p.LYS1359ILE	N/A
Swiss-Prot	VAR_024952	Polymorphism	p.MET1646THR	N/A
Swiss-Prot	VAR_024955	Disease	p.MET1869THR	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024965	Polymorphism	p.MET2397THR	N/A
Swiss-Prot	VAR_054741	Disease	p.MET712VAL	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024942	Polymorphism	p.PRO1262ALA	N/A
Swiss-Prot	VAR_024961	Polymorphism	p.PRO2119LEU	N/A
Swiss-Prot	VAR_033904	Polymorphism	p.PRO755LEU	N/A
Swiss-Prot	VAR_024949	Disease	p.PRO1542SER	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024939	Polymorphism	p.SER1096CYS	N/A
Swiss-Prot	VAR_024941	Disease	p.SER1228THR	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024953	Polymorphism	p.SER1647THR	N/A
Swiss-Prot	VAR_024963	Disease	p.THR2356ILE	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_054747	Disease	p.THR2141MET	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024954	Disease	p.TYR1699CYS	Parkinson disease 8 (PARK8)
Swiss-Prot	VAR_024950	Disease	p.VAL1598GLU	Parkinson disease 8 (PARK8)

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258