Results for the protein: NP

Results for the Protein: NP_001171346

295424143

5122

PCSK1

NCBI

neuroendocrine convertase 1 isoform 2 [Homo sapiens]

Known Diseases associated with this Protein:
OBESITY, SUSCEPTIBILITY TO
PROPROTEIN CONVERTASE 1/3 DEFICIENCY

4

3

4

3

0

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Peptidases_S8_Thermi	cd07484	1.6e-07	73	361
Peptidases_S8_Protei	cd04059	2e-184	74	369
Peptidases_S8_Fervid	cd07485	3.8e-09	81	367
Peptidases_S8_5	cd07489	5e-05	100	396
Peptidases_S8_C5a_Pe	cd07475	2.5e-05	103	404
Peptidases_S8_11	cd04843	0.00014	105	369
Peptidases_S8_Kp43_p	cd04842	9.7e-07	106	369
Peptidases_S8_Autotr	cd04848	5.4e-10	110	369
Peptidases_S8_Subtil	cd07473	8.4e-10	111	369
Peptidases_S8_subtil	cd07474	3.8e-07	111	402
Peptidases_S8_Bacill	cd07481	1.6e-06	111	369
Peptidases_S8_1	cd07487	0.00058	111	369
Peptidases_S8_Subtil	cd07477	4.9e-07	113	367
Peptidases_S8_9	cd07493	0.00038	113	369
Peptidases_S8_13	cd07496	5.3e-08	113	367
Peptidases_S8_Lantib	cd07482	0.00011	113	367
Peptidases_S8_S53	cd00306	5.9e-29	114	367
Peptidases_S8_15	cd07498	2.1e-13	114	367
Peptidase_S8	pfam00082	2.9e-126	94	395
COG4935	COG4935	5.5e-07	428	617
P_proprotein	pfam01483	2.2e-44	457	544
Proho_convert	pfam12177	5.7e-29	665	705

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs6232	Polymorphism	p.ASN174ASP	N/A
dbSNP	rs6234	Polymorphism	p.GLN618GLU	N/A
dbSNP	rs6235	Polymorphism	p.SER643THR	N/A
OMIM	162150.0005	Disease	p.ASN174ASP	OBESITY, SUSCEPTIBILITY TO
OMIM	162150.0003	Disease	p.GLU203TER	PROPROTEIN CONVERTASE 1/3 DEFICIENCY
OMIM	162150.0001	Disease	p.GLY436ARG	PROPROTEIN CONVERTASE 1/3 DEFICIENCY
OMIM	162150.0006	Disease	p.SER260LEU	PROPROTEIN CONVERTASE 1/3 DEFICIENCY

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