Results for the protein: Q9UBS0

Results for the Protein: Q9UBS0

296434560

6199

RPS6KB2

NCBI, UniProt

KS6B2_HUMAN RecName: Full=Ribosomal protein S6 kinase beta-2; Short=S6K-beta-2; Short=S6K2; AltName: Full=70 kDa ribosomal protein S6 kinase 2; Short=P70S6K2; Short=p70-S6K 2; AltName: Full=S6 kinase-related kinase; Short=SRK; AltName: Full=Serine/threonine-protein kinase 14B; AltName: Full=p70 ribosomal S6 kinase beta; Short=S6K-beta; Short=p70 S6 kinase beta; Short=p70 S6K-beta; Short=p70 S6KB; Short=p70-beta

			0 5 0 3 2

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Swiss-Prot Protein: Q9UBS0

Identical to: NP_003943

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK1	cd05622	2.2e-30	24	392
STKc_ROCK	cd05596	7.1e-44	27	391
STKc_TAO1	cd06635	4e-05	37	372
STKc_PAK5	cd06658	1.4e-08	42	346
STKc_PAK6	cd06659	5.8e-12	42	351
STKc_PAK1	cd06654	1.2e-09	43	351
STKc_PAK4	cd06657	1.9e-09	43	346
STKc_TAO3	cd06633	0.00068	43	369
STKc_p38alpha_MAPK14	cd07877	1.5e-06	43	406
STKc_PAK_I	cd06647	3.9e-15	44	349
STKc_PAK2	cd06655	3.7e-10	44	353
STKc_PAK3	cd06656	2.1e-10	44	353
STKc_PAK_II	cd06648	6.7e-12	44	341
STKc_JNK	cd07850	2.1e-07	44	395
STKc_PAK	cd06614	1.5e-17	45	341
STKc_STK10_LOK	cd06644	4e-13	45	348
STKc_p38	cd07851	3.5e-10	45	360
STKc_p38beta_MAPK11	cd07878	3.4e-05	45	372
STKc_p38delta_MAPK13	cd07879	0.00047	45	371
STKc_p38gamma_MAPK12	cd07880	2.3e-06	45	367
STKc_JNK2	cd07876	7.5e-07	46	369
STKc_TAO	cd06607	6.2e-06	47	369
STKc_TAO2	cd06634	2.4e-05	47	370
STKc_myosinIIIA	cd06638	2.3e-10	48	328
STKc_JNK1	cd07875	5.1e-05	48	371
PTKc_FGFR1	cd05098	0.001	49	336
STKc_myosinIIIB	cd06639	5e-10	50	329
STKc_MAP4K4_6	cd06636	1.2e-06	51	328
PTKc_FGFR2	cd05101	0.00041	52	333
STKc_JNK3	cd07874	1.2e-05	54	381
PTKc_FGFR	cd05053	0.0001	55	338
PTKc_FGFR4	cd05099	7.6e-05	55	351
STKc_SLK_like	cd06611	3.2e-13	57	339
PKc_MKK7	cd06618	6.4e-09	58	351
STKc_MST4	cd06640	9.7e-09	58	348
STKc_MST3	cd06641	1.4e-08	58	348
STKc_STK25-YSK1	cd06642	5.5e-09	58	348
STKc_PCTAIRE2	cd07872	3.5e-06	58	342
STKc_PCTAIRE1	cd07873	5e-06	58	342
STKc_MST1_2	cd06612	8.1e-16	59	328
STKc_MAP4K3	cd06645	6.8e-10	59	327
STKc_CDK9	cd07865	5.1e-09	59	328
PTKc_FAK	cd05056	1.3e-07	60	327
PTKc_EGFR_like	cd05057	1.7e-05	60	315
PTK_HER3	cd05111	5.9e-05	60	334
PTKc_ALK_LTK	cd05036	1.8e-08	60	327
PTKc_Srm_Brk	cd05148	4.7e-06	60	328
STKc_ASK	cd06624	1.8e-18	60	328
STKc_TNIK	cd06637	1e-07	60	328
STKc_MAP4K5	cd06646	8e-09	60	327
STKc_ERK1_2_like	cd07849	5.1e-08	60	373
STKc_ERK5	cd07855	1.1e-09	60	361
PTKc_Ror	cd05048	0.00022	61	278
PTKc_Trk	cd05049	3.5e-06	61	325
PTKc_Musk	cd05050	5.7e-05	61	330
PTKc_EphR_A2	cd05063	6.7e-05	61	327
PTKc_EphR_A10	cd05064	2.4e-05	61	332
PTKc_Lck_Blk	cd05067	0.00027	61	358
PTKc_Frk_like	cd05068	1.1e-07	61	327
PTKc_Fyn_Yrk	cd05070	0.0001	61	319
PTKc_Lyn	cd05072	3.3e-05	61	327
PTKc_Hck	cd05073	0.00021	61	319
PTKc_Yes	cd05069	2.4e-05	61	319
PTKc_Csk	cd05082	2.8e-05	61	331
PTKc_Ror1	cd05090	8.5e-05	61	339
PTKc_TrkA	cd05092	2e-05	61	328
PTKc_TrkB	cd05093	2.8e-05	61	334
PTKc_EGFR	cd05108	3.7e-06	61	392
PTKc_HER2	cd05109	2.5e-06	61	329
PTKc_HER4	cd05110	0.00015	61	354
PKc_MEK2	cd06649	3.8e-06	61	422
PKc_MEK1	cd06650	6.7e-06	61	426
STKc_TEY_MAPK_plant	cd07858	1.9e-07	61	389
PTKc_InsR_like	cd05032	3e-05	62	314
PTKc_EphR	cd05033	9.2e-05	62	307
PTKc_Src_like	cd05034	3.1e-07	62	312
PTKc_Csk_like	cd05039	9.1e-06	62	289
PTKc_Tec_like	cd05059	1.3e-05	62	313
PTKc_EphR_B	cd05065	9.7e-05	62	329
PTKc_EphR_A	cd05066	0.00017	62	338
PTKc_Jak1_rpt2	cd05079	3.6e-05	62	332
PTKc_Chk	cd05083	2.6e-05	62	325
PTKc_Tie2	cd05088	0.00011	62	343
PTKc_Itk	cd05112	3.2e-06	62	326
PTKc_Btk_Bmx	cd05113	1.8e-07	62	326
PTKc_Tec_Rlk	cd05114	5.9e-07	62	326
PKc_MAPKK_Byr1_like	cd06620	2.8e-10	62	340
STKc_SLK	cd06643	1.4e-10	62	342
STKc_MAPK15	cd07852	2.3e-11	62	366
STKc_MAPK4_6	cd07854	8.4e-06	62	371
STKc_Sty1_Hog1	cd07856	1e-06	62	378
STKc_BUR1	cd07866	1.9e-08	62	328
STKc_MAP4K3_like	cd06613	1.8e-14	63	327
STKc_CDK12	cd07864	1.1e-09	63	328
STKc_PFTAIRE2	cd07870	8.2e-07	63	328
PTKc_Jak_rpt2	cd05038	2.3e-06	64	320
STKc_myosinIII_like	cd06608	5.1e-13	64	328
STKc_MEKK3_like	cd06625	7.2e-17	64	328
STKc_MEKK3	cd06651	7.9e-11	64	330
STKc_MEKK2	cd06652	2.3e-07	64	329
STKc_MEKK3_like_1	cd06653	2e-09	64	328
STKc_CDK10	cd07845	6.7e-09	64	347
PTKc_Tie1	cd05089	0.00066	65	342
STKc_ROCK_NDR_like	cd05573	4.4e-86	65	390
STKc_phototropin_lik	cd05574	2e-68	65	354
STKc_PDK1	cd05581	1.1e-72	65	328
STKc_LATS	cd05598	2.8e-54	65	393
STKc_DMPK_like	cd05597	6.2e-62	65	390
STKc_NDR_like	cd05599	9.1e-39	65	393
STKc_Sid2p_Dbf2p	cd05600	1e-24	65	391
STKc_CRIK	cd05601	1.4e-38	65	390
STKc_MAST	cd05609	1.8e-60	65	359
STKc_PRKX_like	cd05612	9.2e-104	65	362
STKc_MRCK_alpha	cd05623	3.6e-47	65	391
STKc_MRCK_beta	cd05624	2.8e-46	65	390
STKc_LATS1	cd05625	2.8e-39	65	393
STKc_LATS2	cd05626	7.4e-39	65	393
STKc_NDR2	cd05627	2e-40	65	420
STKc_NDR1	cd05628	1.2e-38	65	393
STKc_NDR_like_fungal	cd05629	4.2e-58	65	393
STKc_MST3_like	cd06609	1.6e-17	65	345
STKc_OSR1_SPAK	cd06610	1e-13	65	328
PKc_MEK	cd06615	1.5e-10	65	345
PKc_MKK3_6	cd06617	8.3e-10	65	345
PKc_MKK5	cd06619	6.1e-05	65	353
PKc_MAPKK_Pek1_like	cd06621	8.7e-10	65	337
PKc_MAPKK_plant_like	cd06623	9.5e-18	65	333
PKc_MAPKK_PBS2_like	cd06622	2.6e-10	65	387
STKc_NAK1_like	cd06917	2.1e-13	65	342
STKc_CdkB_plant	cd07837	3.6e-13	65	329
STKc_CDC2L1	cd07843	1.6e-09	65	328
STKc_PCTAIRE_like	cd07844	8.9e-08	65	328
STKc_CDKL2_3	cd07846	7e-10	65	328
STKc_CDKL1_4	cd07847	1.7e-08	65	358
STKc_CDKL5	cd07848	2e-07	65	328
STKc_CDK6	cd07862	8e-08	65	354
STKc_CDC2L6	cd07867	0.001	65	328
STKc_PFTAIRE1	cd07869	4e-05	65	367
STKc_PCTAIRE3	cd07871	2.8e-07	65	328
STKc_Nek6_Nek7	cd08224	5.7e-10	65	331
STKc_Nek7	cd08229	2e-10	65	331
SPS1	COG0515	7.4e-71	65	470
PTKc_RET	cd05045	0.00013	66	307
PKc_STE	cd05122	1.6e-43	66	327
STKc_Yank1	cd05578	7e-75	66	328
STKc_GRK4_like	cd05605	1.2e-66	66	349
STKc_MSK1_N	cd05613	2.3e-115	66	347
STKc_cPKC_alpha	cd05615	2.2e-83	66	391
STKc_GRK6	cd05630	7.2e-59	66	349
STKc_GRK4	cd05631	8.5e-58	66	349
STKc_GRK5	cd05632	1.1e-58	66	349
STKc_MAPKKK	cd06606	6.5e-42	66	328
STKc_Cdc7_like	cd06627	1.7e-21	66	328
STKc_CCRK	cd07832	3.1e-14	66	329
STKc_MAPK	cd07834	8.8e-12	66	370
STKc_Pho85	cd07836	4.5e-09	66	328
STKc_CDK5	cd07839	1.5e-08	66	328
STKc_CDK7	cd07841	4.3e-12	66	337
STKc_CDK8_like	cd07842	2.1e-09	66	328
STKc_NLK	cd07853	6.8e-07	66	426
STKc_MPK1	cd07857	9.9e-09	66	366
STKc_TDY_MAPK_plant	cd07859	3.1e-08	66	406
STKc_CDK2_3	cd07860	8e-13	66	328
STKc_CDK4	cd07863	3.6e-08	66	328
STKc_Nek	cd08215	3.7e-55	66	328
STKc_Nek8	cd08220	3.6e-15	66	328
STKc_Nek9	cd08221	3.1e-10	66	328
STKc_Nek11	cd08222	1.6e-17	66	328
STKc_Nek4	cd08223	4.8e-26	66	328
STKc_Nek5	cd08225	6.9e-28	66	328
STKc_Nek2	cd08217	4.4e-18	66	328
STKc_Nek10	cd08528	8.9e-17	66	318
STKc_CNK2-like	cd08530	1.1e-14	66	328
PTKc_Axl_like	cd05035	0.00059	67	331
PTKc_Abl	cd05052	1.8e-06	67	332
PTKc_Tyro3	cd05074	1.6e-05	67	329
PTKc_Tyk2_rpt2	cd05080	9.5e-06	67	330
PTKc_Jak2_Jak3_rpt2	cd05081	9.3e-07	67	359
STKc_CMGC	cd05118	2e-17	67	328
STKc_PKA	cd05580	5.5e-123	67	361
STKc_MSK_N	cd05583	3.5e-133	67	347
STKc_cPKC	cd05587	2.9e-98	67	391
STKc_PKN	cd05589	2.5e-111	67	390
STKc_cPKC_beta	cd05616	5.5e-86	67	391
STKc_MSK2_N	cd05614	6.7e-135	67	392
PKc_MAPKK	cd06605	9.3e-14	67	332
PKc_MKK4	cd06616	7.9e-07	67	349
STKc_MAPKKK_Bck1_lik	cd06629	9.6e-14	67	328
STKc_CDK_like	cd07829	2.4e-18	67	328
STKc_MAK_like	cd07830	3.4e-13	67	328
STKc_CDKL	cd07833	4.2e-11	67	328
STKc_CDK1_like	cd07835	1.6e-11	67	328
STKc_CDK4_6_like	cd07838	3.6e-13	67	328
STKc_CDK9_like	cd07840	1.3e-12	67	328
STKc_CDK1_euk	cd07861	1.3e-10	67	328
STKc_Nek1	cd08218	4.3e-35	67	328
STKc_Nek3	cd08219	8.7e-34	67	327
STKc_Nek6	cd08228	8.2e-09	67	326
STKc_FA2-like	cd08529	8.7e-16	67	328
STKc_MAPKKK_Byr2_lik	cd06628	1.4e-17	68	328
PK_STRAD	cd08216	0.00017	68	339
STKc_MEKK4	cd06626	1.1e-16	69	328
STKc_RSK_N	cd05582	1.3e-147	70	390
STKc_p70S6K	cd05584	7.5e-245	70	392
STKc_Rim15_like	cd05611	6.2e-20	70	334
STKc_MOK	cd07831	2.3e-12	70	328
PTKc	cd00192	2.2e-11	71	327
PTKc_Fes_like	cd05041	5.6e-08	71	324
PTKc_Ack_like	cd05040	9.6e-08	71	323
PTKc_c-ros	cd05044	4.6e-07	71	329
PTKc_Tie	cd05047	0.00035	71	329
PTKc_Met_Ron	cd05058	3.7e-05	71	331
PTKc_Syk_like	cd05060	0.00025	71	309
PTKc_Fes	cd05084	7.2e-08	71	323
PTKc_Fer	cd05085	1e-05	71	328
PTKc_Syk	cd05116	4.2e-06	71	330
PTK_Jak2_Jak3_rpt1	cd05078	0.00047	71	332
STKc_PKC	cd05570	4.2e-109	71	390
STKc_PKB	cd05571	1.5e-113	71	392
STKc_SGK	cd05575	4.7e-126	71	390
STKc_nPKC_eta	cd05590	7.2e-100	71	391
STKc_nPKC_epsilon	cd05591	2.5e-99	71	391
STKc_nPKC_theta_delt	cd05592	3.7e-91	71	392
STKc_PKB_gamma	cd05593	4.1e-95	71	395
STKc_PKB_alpha	cd05594	1.9e-101	71	393
STKc_PKB_beta	cd05595	3.3e-108	71	392
STKc_SGK1	cd05602	4.2e-106	71	392
STKc_SGK2	cd05603	5.4e-109	71	391
STKc_SGK3	cd05604	1.1e-105	71	392
STKc_aPKC_zeta	cd05617	1.3e-73	71	391
STKc_aPKC_iota	cd05618	1.5e-76	71	391
STKc_nPKC_theta	cd05619	4.7e-83	71	392
STKc_nPKC_delta	cd05620	1e-73	71	392
STKc_aPKC	cd05588	6.4e-91	71	391
STKc_MEKK1	cd06630	1.3e-12	71	329
STKc_MEKK1_plant	cd06632	3.8e-17	71	328
STKc_YSK4	cd06631	5.7e-14	71	328
STKc_beta_ARK	cd05606	6.9e-59	72	348
STKc_GRK3	cd05633	4e-49	72	349
PKc	cd00180	4.5e-72	73	326
PTKc_Aatyk	cd05042	0.00019	73	306
PTKc_Zap-70	cd05115	2.1e-05	73	328
STKc_AGC	cd05123	1.3e-165	73	328
STKc_cGK_PKG	cd05572	2.5e-89	73	335
STKc_GRK	cd05577	2e-58	73	348
STKc_YPK1_like	cd05585	2.2e-116	73	389
STKc_Sck1_like	cd05586	1.4e-98	73	435
STKc_GRK7	cd05607	2.7e-54	73	348
STKc_GRK1	cd05608	6.1e-56	73	348
STKc_MAST_like	cd05579	1.8e-66	73	333
Pkinase	pfam00069	1.1e-93	67	328
Pkinase_C	pfam00433	3.4e-15	348	393
Pkinase_Tyr	pfam07714	4.4e-14	67	328
TyrKc	smart00219	1.6e-12	67	328
STYKc	smart00221	2.6e-96	67	328
S_TKc	smart00220	2.6e-109	77	328
KIND	smart00750	0.00092	160	336
S_TK_X	smart00133	4.4e-21	329	391

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs13859	Polymorphism	p.ALA420VAL	N/A
dbSNP	rs4930427	Polymorphism	p.PHE269LEU	N/A
dbSNP	rs55987642	Polymorphism	p.PRO267LEU	N/A
Swiss-Prot	VAR_040646	Polymorphism	p.THR443MET	N/A
Swiss-Prot	VAR_040644	Polymorphism	p.VAL368MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258