Results for the protein: Q2M3G0

Results for the Protein: Q2M3G0

308153645

340273

ABCB5

NCBI, UniProt

ABCB5_HUMAN RecName: Full=ATP-binding cassette sub-family B member 5; AltName: Full=ABCB5 P-gp; AltName: Full=P-glycoprotein ABCB5

			0 12 0 7 5

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Swiss-Prot Protein: Q2M3G0

Identical to: NP_848654

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
ABCC_MRP_domain2	cd03244	3e-16	1	161
ABCC_bacteriocin_exp	cd03245	1.3e-16	1	159
ABCC_TAP	cd03248	3.3e-29	1	155
ABCC_MsbA	cd03251	7.3e-64	1	175
ABCC_Hemolysin	cd03252	4e-48	1	178
ABC_MTABC3_MDL1_MDL2	cd03249	2.7e-88	1	178
ABCC_ATM1_transporte	cd03253	3.8e-54	2	178
ABCC_Glucan_exporter	cd03254	6.5e-53	2	169
ABCC_Protease_Secret	cd03246	1.2e-19	3	155
ABCC_cytochrome_bd	cd03247	3.4e-14	3	159
ABC_ATPase	cd00267	4.1e-13	6	154
MdlB	COG1132	8.1e-159	230	812
Uup	COG0488	1.1e-05	316	802
COG1123	COG1123	3.7e-11	319	810
ABCC_SUR2	cd03288	7.3e-18	498	810
ABCC_CFTR1	cd03291	5.5e-07	524	812
ModF	COG1119	1.7e-10	534	792
TagH	COG1134	1.2e-07	550	810
Ttg2A	COG1127	3.5e-14	557	812
ABCC_TAP	cd03248	3.3e-88	563	786
PstB	COG1117	2.4e-14	563	799
YhbG	COG1137	6.1e-09	563	805
ZnuC	COG1121	7.1e-11	566	804
CcmA	COG1131	3.9e-24	566	808
ABCG_EPDR	cd03213	8.6e-14	567	790
ABCG_PDR_domain2	cd03232	7.9e-06	567	784
ABCG_PDR_domain1	cd03233	9.5e-06	567	790
ABCG_White	cd03234	7.5e-10	567	790
ABCC_NFT1	cd03369	2.1e-18	567	792
sufC	COG0396	2.2e-10	567	810
LivF	COG0410	9.9e-13	567	805
TauB	COG1116	8.5e-14	567	812
CbiO	COG1122	1.2e-40	567	804
DppF	COG1124	2.2e-15	567	809
ABCC_MRP_domain2	cd03244	5.3e-57	568	792
ABCC_bacteriocin_exp	cd03245	3.5e-61	568	790
ABCC_Glucan_exporter	cd03254	1.2e-103	568	800
ABCC_CFTR2	cd03289	1.8e-07	568	812
CysA	COG1118	4.4e-08	568	812
FepC	COG1120	1.6e-13	568	811
GlnQ	COG1126	1.3e-18	568	807
ABC_RNaseL_inhibitor	cd03236	0.00047	569	804
ABC_MetN_methionine_	cd03258	1.4e-18	569	800
ABC_NikE_OppD_transp	cd03257	1.2e-29	569	790
ABC_CysA_sulfate_imp	cd03296	2.5e-23	569	810
DppD	COG0444	3.6e-10	569	812
PhnK	COG1101	2.3e-10	569	806
OpuBA	COG1125	5.5e-09	569	812
AbcC	COG1135	7.1e-12	569	812
SalX	COG1136	5.5e-28	569	792
ABC_Carb_Monos_I	cd03216	3.1e-17	570	789
ABC_Mj1267_LivG_bran	cd03219	3.1e-15	570	801
ABC_KpsT_Wzt	cd03220	3.1e-12	570	790
ABCF_EF-3	cd03221	2.1e-10	570	785
ABC_YhbG	cd03218	6.6e-08	570	800
ABCD_peroxisomal_ALD	cd03223	3.1e-11	570	786
ABC_TM1139_LivF_bran	cd03224	9.6e-16	570	798
ABCC_MRP_Like	cd03228	7.9e-112	570	785
ABC_DR_subfamily_A	cd03230	3.4e-34	570	786
ABC_Class3	cd03229	2e-43	570	785
ABCC_Protease_Secret	cd03246	1.5e-58	570	786
ABCC_cytochrome_bd	cd03247	1.3e-57	570	790
ABCC_MRP_domain1	cd03250	4.3e-22	570	785
ABCC_MsbA	cd03251	9.9e-106	570	806
ABCC_Hemolysin	cd03252	2.2e-94	570	809
ABCC_ATM1_transporte	cd03253	1.4e-100	570	809
ABC_MJ0796_LolCDE_Ft	cd03255	2e-25	570	786
ABC_PhnC_transporter	cd03256	1.3e-15	570	802
ABC_Carb_Solutes_lik	cd03259	8.9e-28	570	790
ABC_PstB_phosphate_t	cd03260	2.5e-42	570	795
ABC_Org_Solvent_Resi	cd03261	8.5e-17	570	806
ABC_HisP_GlnQ	cd03262	1.6e-18	570	786
ABC_subfamily_A	cd03263	1.6e-13	570	796
ABC_drug_resistance_	cd03264	1.5e-12	570	790
ABC_NatA_sodium_expo	cd03266	3.9e-10	570	790
ABC_NatA_like	cd03267	6.3e-07	570	790
ABC_MTABC3_MDL1_MDL2	cd03249	1.3e-159	570	809
ABC_putative_ATPase	cd03269	8.3e-12	570	790
ABC_BcrA_bacitracin_	cd03268	8.6e-11	570	790
ABC_FtsE_transporter	cd03292	1e-13	570	786
ABC_NrtD_SsuB_transp	cd03293	1.2e-21	570	794
ABC_Pro_Gly_Betaine	cd03294	2e-15	570	811
ABC_OpuCA_Osmoprotec	cd03295	2.2e-16	570	812
ABC_MalK_N	cd03301	1e-13	570	790
ABC_PotA_N	cd03300	1.7e-16	570	795
ABC_ATPase	cd00267	2.5e-60	571	785
ABC_Iron-Siderophore	cd03214	1.4e-22	571	790
ABC_cobalt_CbiO_doma	cd03225	1.1e-35	571	785
ABC_cobalt_CbiO_doma	cd03226	1.1e-19	571	787
ABC_Metallic_Cations	cd03235	2.5e-13	571	790
ABCC_SUR1_N	cd03290	2.5e-15	572	785
ABC_CcmA_heme_export	cd03231	1.3e-06	574	787
ABC_ModC_molybdenum_	cd03297	5.2e-12	574	790
ABC_RNaseL_inhibitor	cd03222	0.00058	577	804
ABC_FeS_Assembly	cd03217	2.5e-10	581	802
ABC_ModC_like	cd03299	1.1e-14	581	811
ABC_Carb_Monos_II	cd03215	5.9e-09	582	786
LivG	COG0411	6.6e-11	583	800
ABC_DrrA	cd03265	2.8e-11	584	796
ABC_ThiQ_thiamine_tr	cd03298	1.7e-11	584	790
ABC_UvrA_II	cd03271	0.00095	588	792
ABC_tran	pfam00005	8.1e-25	2	108
SunT	COG2274	2.5e-69	96	810
COG4178	COG4178	0.0003	179	804
PvdE	COG4615	1.3e-09	230	800
CydD	COG4988	1.2e-25	246	812
ABC_membrane	pfam00664	9.7e-57	247	523
ArpD	COG4618	2.8e-16	258	809
CydC	COG4987	2.6e-13	268	809
ATM1	COG5265	5.1e-65	307	808
COG4172	COG4172	1.3e-08	391	812
COG4674	COG4674	6.3e-07	557	810
PhnK	COG4107	6.9e-05	564	812
HisP	COG4598	9.8e-17	564	812
COG4181	COG4181	3.5e-12	565	790
SapF	COG4167	1.3e-07	566	812
ProV	COG4175	2.2e-07	566	809
PhnL	COG4778	5.7e-06	566	775
COG3638	COG3638	1e-14	567	812
MalK	COG3839	4.6e-12	567	809
PotA	COG3842	9.3e-10	567	811
CcmA	COG4133	3e-07	568	787
COG4136	COG4136	1.4e-07	568	789
TauB	COG4525	1.5e-11	568	810
FtsE	COG2884	1.3e-13	569	794
ThiQ	COG3840	2.5e-11	569	804
ArtP	COG4161	5.1e-16	569	809
COG4559	COG4559	1.2e-06	569	812
AppF	COG4608	2.9e-13	569	811
NatA	COG4555	3e-15	570	811
CeuD	COG4604	1.9e-07	570	804
COG4619	COG4619	8.7e-18	570	800
BtuD	COG4138	1.9e-05	584	810
ABC_tran	pfam00005	1.4e-36	612	739
AAA	smart00382	6e-05	23	170
AAA	smart00382	6.9e-35	597	807

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_062662	Polymorphism	p.ALA435THR	N/A
dbSNP	rs17143304	Polymorphism	p.ALA470THR	N/A
dbSNP	rs58795451	Polymorphism	p.ASP742GLY	N/A
dbSNP	rs35885925	Polymorphism	p.GLN460HIS	N/A
Swiss-Prot	VAR_028390	Polymorphism	p.GLU525LYS	N/A
dbSNP	rs59334881	Polymorphism	p.GLU679LYS	N/A
Swiss-Prot	VAR_035731	Polymorphism	p.GLU230VAL	N/A
dbSNP	rs62453384	Polymorphism	p.GLY365VAL	N/A
dbSNP	rs60197951	Polymorphism	p.ILE648THR	N/A
Swiss-Prot	VAR_028388	Polymorphism	p.LYS224ARG	N/A
Swiss-Prot	VAR_028387	Polymorphism	p.LYS115GLU	N/A
dbSNP	rs34603556	Polymorphism	p.MET1THR	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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