Results for the protein: Q13627

Results for the Protein: Q13627

3219996

1859

DYRK1A

NCBI, UniProt

DYR1A_HUMAN RecName: Full=Dual specificity tyrosine-phosphorylation-regulated kinase 1A; AltName: Full=Dual specificity YAK1-related kinase; AltName: Full=HP86; AltName: Full=Protein kinase minibrain homolog; Short=MNBH; Short=hMNB

			0 3 0 0 3

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Swiss-Prot Protein: Q13627

Identical to: NP_001387

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_TAO1	cd06635	0.00051	131	429
STKc_PAK5	cd06658	0.00092	134	424
STKc_PAK6	cd06659	0.00021	135	427
STKc_JNK1	cd07875	7.7e-09	136	505
STKc_PAK1	cd06654	0.00061	137	446
STKc_PAK2	cd06655	0.0002	138	447
STKc_PAK3	cd06656	0.00095	138	448
STKc_myosinIIIA	cd06638	1.4e-07	140	427
STKc_myosinIIIB	cd06639	3.1e-06	140	409
STKc_JNK2	cd07876	9.1e-10	140	518
STKc_TAO2	cd06634	9.7e-06	141	430
STKc_TAO	cd06607	0.00015	142	429
STKc_MAP4K4_6	cd06636	0.00014	142	427
STKc_PAK_II	cd06648	4.5e-06	142	427
STKc_ASK	cd06624	1.6e-06	143	416
STKc_CDK9	cd07865	1.3e-15	143	479
STKc_JNK	cd07850	1.4e-12	144	510
STKc_p38delta_MAPK13	cd07879	1.8e-06	144	497
STKc_JNK3	cd07874	2.3e-10	144	524
STKc_STK10_LOK	cd06644	1.2e-07	145	446
STKc_p38alpha_MAPK14	cd07877	3.5e-08	145	497
STKc_p38gamma_MAPK12	cd07880	1e-10	145	498
STKc_p38beta_MAPK11	cd07878	9.8e-09	146	515
PKc_MKK7	cd06618	1.2e-06	147	458
STKc_Sty1_Hog1	cd07856	1.5e-11	148	503
STKc_p38	cd07851	3.8e-15	148	526
STKc_SLK	cd06643	5.3e-07	150	444
STKc_MST4	cd06640	2.6e-05	151	453
STKc_MST3	cd06641	0.00013	151	453
STKc_STK25-YSK1	cd06642	4e-05	151	416
STKc_TNIK	cd06637	7.4e-06	152	420
STKc_CDK10	cd07845	5.9e-14	152	497
STKc_CDK12	cd07864	4.5e-15	152	479
STKc_PCTAIRE2	cd07872	1.9e-08	152	499
STKc_PCTAIRE1	cd07873	2.5e-07	152	461
PTKc_Yes	cd05069	0.00089	153	415
PTKc_FAK	cd05056	0.00011	153	410
STKc_SLK_like	cd06611	1.9e-06	153	414
PKc_MEK2	cd06649	0.00017	153	508
PKc_MEK1	cd06650	0.00013	153	512
STKc_ERK1_2_like	cd07849	1.3e-12	153	514
STKc_MAPK15	cd07852	1.3e-15	153	491
STKc_phototropin_lik	cd05574	9.7e-06	154	428
STKc_MAPKKK_Byr2_lik	cd06628	1.6e-08	154	418
STKc_MAPKKK_Bck1_lik	cd06629	1.1e-05	154	402
STKc_NAK1_like	cd06917	3e-06	154	416
STKc_TEY_MAPK_plant	cd07858	5.3e-20	154	524
STKc_BUR1	cd07866	2.2e-11	154	479
PTKc_InsR_like	cd05032	0.00015	155	407
PTKc_Jak_rpt2	cd05038	1.2e-06	155	406
PTKc_Trk	cd05049	0.00012	155	407
PTKc_Abl	cd05052	0.0006	155	427
PTKc_Frk_like	cd05068	2.7e-05	155	408
PTKc_Jak2_Jak3_rpt2	cd05081	2.5e-05	155	431
STKc_ERK5	cd07855	8.6e-15	155	514
PTKc_Musk	cd05050	1.7e-05	156	429
PTKc_Tec_like	cd05059	0.00037	156	403
PTKc_Itk	cd05112	0.0002	156	427
PTKc_Btk_Bmx	cd05113	7.1e-05	156	427
STKc_MAP4K3_like	cd06613	8.7e-08	156	403
PKc_MKK3_6	cd06617	2e-07	156	432
STKc_PCTAIRE_like	cd07844	1.4e-19	156	479
STKc_CDC2L6	cd07867	9.7e-07	156	479
STKc_CDK8	cd07868	1.7e-06	156	479
STKc_PFTAIRE1	cd07869	2.5e-06	156	491
STKc_PFTAIRE2	cd07870	1.5e-09	156	479
STKc_PCTAIRE3	cd07871	2.8e-09	156	479
STKc_Nek6_Nek7	cd08224	3.1e-06	156	396
STKc_Nek6	cd08228	8.8e-05	156	413
STKc_Nek7	cd08229	8.5e-07	156	413
STKc_ROCK_NDR_like	cd05573	6.2e-10	157	453
STKc_PKA	cd05580	3.2e-08	157	448
STKc_PDK1	cd05581	1.4e-14	157	395
STKc_DMPK_like	cd05597	0.0002	157	484
STKc_Sid2p_Dbf2p	cd05600	0.00014	157	441
STKc_CRIK	cd05601	2.2e-05	157	479
STKc_MAST	cd05609	1.5e-05	157	480
STKc_PRKX_like	cd05612	7.7e-08	157	444
STKc_MRCK_alpha	cd05623	0.00024	157	483
STKc_MRCK_beta	cd05624	3.2e-05	157	484
STKc_MST3_like	cd06609	2.9e-08	157	416
STKc_OSR1_SPAK	cd06610	9.8e-08	157	395
STKc_MST1_2	cd06612	4.2e-11	157	395
STKc_myosinIII_like	cd06608	7.3e-08	157	404
PKc_MEK	cd06615	7.8e-08	157	497
PKc_MAPKK_Byr1_like	cd06620	6.3e-05	157	485
PKc_MAPKK_plant_like	cd06623	1.5e-10	157	410
STKc_MEKK2	cd06652	4.5e-05	157	405
STKc_MEKK3_like_1	cd06653	6.3e-06	157	428
STKc_CDKL	cd07833	4.3e-18	157	479
STKc_CDC2L1	cd07843	2.4e-16	157	479
STKc_CdkB_plant	cd07837	3e-16	157	480
STKc_CDKL2_3	cd07846	7.4e-14	157	479
STKc_CDKL1_4	cd07847	2.8e-25	157	479
STKc_CDKL5	cd07848	6.3e-16	157	479
STKc_CDK6	cd07862	2e-07	157	479
SPS1	COG0515	1.3e-51	157	668
PKc_STE	cd05122	2.2e-12	158	403
STKc_Yank1	cd05578	7.1e-08	158	404
STKc_MSK_N	cd05583	0.00012	158	417
STKc_cPKC	cd05587	2.1e-07	158	483
STKc_GRK4_like	cd05605	2.3e-06	158	453
STKc_MSK1_N	cd05613	0.001	158	417
STKc_MSK2_N	cd05614	0.00097	158	477
STKc_cPKC_alpha	cd05615	3.5e-06	158	480
STKc_cPKC_beta	cd05616	2.7e-05	158	511
STKc_GRK6	cd05630	0.0004	158	442
STKc_GRK4	cd05631	7.7e-06	158	464
STKc_GRK5	cd05632	2.4e-05	158	464
STKc_MAPKKK	cd06606	8.1e-17	158	398
STKc_Cdc7_like	cd06627	1.8e-13	158	404
STKc_YSK4	cd06631	0.00059	158	427
STKc_MEKK3	cd06651	2.2e-06	158	423
STKc_CCRK	cd07832	2.8e-19	158	480
STKc_MAPK	cd07834	8.4e-19	158	500
STKc_CDK7	cd07841	9.3e-17	158	488
STKc_Pho85	cd07836	6.8e-27	158	479
STKc_CDK8_like	cd07842	2.2e-14	158	479
STKc_CDK5	cd07839	1.2e-11	158	479
STKc_NLK	cd07853	5.4e-10	158	568
STKc_MPK1	cd07857	8.4e-14	158	507
STKc_TDY_MAPK_plant	cd07859	9.6e-16	158	497
STKc_CDK2_3	cd07860	1.7e-24	158	479
STKc_CDK1_euk	cd07861	8.3e-29	158	479
STKc_CDK4	cd07863	5.1e-22	158	479
STKc_Nek	cd08215	2.3e-14	158	395
STKc_Nek2	cd08217	1.7e-10	158	395
STKc_Nek1	cd08218	3.6e-05	158	424
STKc_Nek3	cd08219	4.6e-08	158	410
STKc_Nek8	cd08220	8.9e-07	158	428
STKc_Nek9	cd08221	2.1e-07	158	399
STKc_Nek11	cd08222	6.1e-06	158	416
STKc_Nek4	cd08223	0.00023	158	416
STKc_Nek5	cd08225	1.6e-05	158	416
STKc_Nek10	cd08528	3.1e-06	158	400
STKc_FA2-like	cd08529	3.4e-06	158	391
STKc_CNK2-like	cd08530	6.8e-09	158	398
PTKc_Src_like	cd05034	7.7e-05	159	398
STKc_CMGC	cd05118	7.1e-38	159	479
STKc_PKN	cd05589	2e-06	159	458
PKc_MAPKK	cd06605	1.6e-06	159	410
PKc_MKK4	cd06616	1.1e-07	159	457
PKc_MAPKK_PBS2_like	cd06622	2.3e-06	159	453
STKc_CDK_like	cd07829	7.7e-26	159	479
STKc_MOK	cd07831	1.8e-20	159	479
STKc_MAK_like	cd07830	3.4e-21	159	479
STKc_CDK4_6_like	cd07838	1.9e-18	159	479
STKc_CDK9_like	cd07840	4.9e-18	159	479
STKc_MAPK4_6	cd07854	5e-10	159	508
STKc_CDK1_like	cd07835	3.6e-32	159	479
STKc_p70S6K	cd05584	1e-06	162	495
STKc_MEKK4	cd06626	4.7e-11	162	404
PTKc	cd00192	8.3e-06	163	428
PTKc_Ack_like	cd05040	1.5e-07	163	400
PTKc_Fes_like	cd05041	0.00028	163	407
STKc_PKB	cd05571	2.2e-07	163	518
STKc_SGK	cd05575	5.3e-06	163	510
STKc_RSK_N	cd05582	9.6e-05	163	479
STKc_aPKC	cd05588	6.3e-06	163	483
STKc_nPKC_eta	cd05590	4.4e-05	163	464
STKc_nPKC_epsilon	cd05591	9.5e-08	163	480
STKc_nPKC_theta_delt	cd05592	1.3e-08	163	484
STKc_PKB_gamma	cd05593	9.3e-05	163	480
STKc_PKB_alpha	cd05594	3.3e-06	163	517
STKc_PKB_beta	cd05595	0.00018	163	519
STKc_PKC	cd05570	1.5e-09	163	458
STKc_SGK1	cd05602	6.2e-06	163	526
STKc_SGK2	cd05603	2.7e-06	163	522
STKc_SGK3	cd05604	0.00071	163	519
STKc_aPKC_zeta	cd05617	7.4e-06	163	451
STKc_nPKC_theta	cd05619	8.9e-07	163	484
STKc_nPKC_delta	cd05620	4.8e-05	163	470
STKc_MEKK1	cd06630	1.3e-05	163	402
STKc_beta_ARK	cd05606	0.00026	164	439
STKc_GRK3	cd05633	0.00052	164	440
STKc_MEKK3_like	cd06625	3.4e-09	164	429
STKc_MEKK1_plant	cd06632	4.7e-07	164	395
PKc	cd00180	6.5e-53	165	477
STKc_AGC	cd05123	4.9e-13	165	395
STKc_GRK	cd05577	1.8e-08	165	418
STKc_MAST_like	cd05579	3e-10	165	403
STKc_cGK_PKG	cd05572	3e-09	165	405
STKc_YPK1_like	cd05585	1.8e-06	165	483
STKc_GRK7	cd05607	3.1e-06	165	438
STKc_GRK1	cd05608	1.1e-06	165	448
STKc_Sck1_like	cd05586	6.7e-05	165	528
Pkinase	pfam00069	2e-49	159	479
Pkinase_Tyr	pfam07714	1.2e-09	159	405
TyrKc	smart00219	6.8e-07	159	402
STYKc	smart00221	7.2e-71	159	479
S_TKc	smart00220	1.2e-80	169	479

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040453	Polymorphism	p.ALA679PRO	N/A
Swiss-Prot	VAR_009396	Polymorphism	p.GLN681HIS	N/A
Swiss-Prot	VAR_009395	Polymorphism	p.TYR415PHE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258