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Results for the Protein: Q9HCK4
49036496

ROBO2_HUMAN RecName: Full=Roundabout homolog 2; Flags: Precursor

Known Diseases associated with this Protein:
  VESICOURETERAL REFLUX 2
  VESICOURETERAL REFLUX 2 (VUR2)
4
0
2
0
2
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

Ig3_Contactin_like - cd04968
Ig1_Robo - cd07693
Ig3_NCAM-1_like - cd05730
Ig1_Contactin-2 - cd05850
Ig1_Contactin-1 - cd05849
Ig1_Contactin-5 - cd05848
I-set - pfam07679
Ig1_Contactin - cd04967
Ig1_Neogenin - cd05722
Ig4_Contactin-2-like - cd05728
Ig2_Robo - cd05724
Ig2_FGFR_like - cd05729
IG - smart00409
IG_like - smart00410
IGc2 - smart00408
Ig3_Peroxidasin - cd05745
Ig_2 - cd05764
Ig5_Contactin_like - cd04969
Ig4_L1-NrCAM_like - cd04978
Ig4_Neogenin - cd05723
Ig3_Robo - cd05725
Ig6_L1-CAM_like - cd05733
Ig_1 - cd05763
Ig2_RPTP_IIa_LAR_lik - cd05738
Ig - cd00096
Ig6_NrCAM - cd05874
Ig6_hNeurofascin_lik - cd05875
Ig_C5_MyBP-C - cd05894
ig - pfam00047
Ig_3 - cd05765
Ig4_Peroxidasin - cd05746
Ig_Myotilin_C_like - cd05744
Ig5_NCAM-1_like - cd05732
Ig5_Titin_like - cd05747
Ig_TrkABC_d4 - cd04972
Ig2_FGFRL1-like - cd05856
Ig_Myomesin_like_C - cd05737
Ig2_FGFR - cd05857
Ig3_L1-CAM - cd05876
Ig5_Contactin-1 - cd05852
Ig6_Contactin_like - cd04970
Ig_Titin_like - cd05748
Ig2_PTK7 - cd05760
Ig3_FGFR - cd04974
Ig3_L1-CAM_like - cd05731
Ig2_Follistatin_like - cd05736
Ig_Pro_neuregulin - cd05750
Ig3_Contactin-1 - cd05851
Ig3_Perlecan_like - cd05754
V-set - pfam07686
Ig_Perlecan_D2_like - cd05743
Ig4_Robo - cd05726
Ig_CEACAM_D1_like - cd05741
Ig5_NCAM-2 - cd05870
FN3 - cd00063
FN3 - smart00060
fn3 - pfam00041


Swiss-Prot Protein: Q9HCK4
Identical to: NP_002933
   Default View:








































Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
Ig3_NCAM-1_likecd057302.6e-0530131
Ig1_Robocd076932.1e-8230129
Ig1_Contactincd049672.1e-0631125
Ig1_Contactin-5cd058484.1e-1031128
Ig1_Contactin-1cd058490.0005531128
Ig1_Contactin-2cd058500.0006831128
Ig1_Neogenincd057221.5e-2232128
Ig4_Contactin-2-likecd057282e-0534128
Ig2_Robocd057241.1e-1035128
Ig2_FGFR_likecd057290.0003537128
Ig3_Peroxidasincd057458.9e-0544128
Ig5_Contactin_likecd049692.5e-0645128
Ig4_L1-NrCAM_likecd049781.8e-0645129
Ig_2cd057640.0008245130
Ig4_Neogenincd057236.7e-0547128
Igcd000966.3e-1148127
Ig6_L1-CAM_likecd057335.6e-0748127
Ig2_RPTP_IIa_LAR_likcd057380.0003548129
Ig_1cd057636.6e-0848129
Ig3_Robocd057250.0001248128
Ig6_NrCAMcd058742.2e-0848127
Ig6_hNeurofascin_likcd058751.4e-0648127
Ig3_Contactin_likecd049683e-05132222
Ig1_Neogenincd057222.7e-06134221
Ig4_Contactin-2-likecd057281.3e-06134221
Ig3_NCAM-1_likecd057306.2e-06134224
Ig1_Contactincd049672.7e-06135218
Ig1_Contactin-5cd058480.00085135221
Ig1_Contactin-1cd058499.1e-07135221
Ig2_Robocd057249.1e-47137221
Ig1_Robocd076933e-07137222
Ig_C5_MyBP-Ccd058940.00053138223
Ig2_FGFR_likecd057290.00019139221
Ig5_Contactin_likecd049698.9e-09147221
Ig4_L1-NrCAM_likecd049780.0001147222
Ig_2cd057640.00039147221
Ig_3cd057650.00063147221
Igcd000962.8e-11150220
Ig2_RPTP_IIa_LAR_likcd057388.9e-08150222
Ig4_Peroxidasincd057460.00032150220
Ig_Myotilin_C_likecd057440.00021150221
Ig_1cd057630.00059150222
Ig3_Robocd057257.4e-05150221
Ig5_NCAM-1_likecd057329.2e-05221310
Ig3_Contactin_likecd049689.5e-06224311
Ig5_Titin_likecd057474e-08224309
Ig1_Contactincd049670.00013225305
Ig_TrkABC_d4cd049721.9e-06225310
Ig3_NCAM-1_likecd057306.4e-06225313
Ig1_Contactin-1cd058498.1e-05225310
Ig1_Neogenincd057220.00013226310
Ig4_Contactin-2-likecd057282.2e-05226310
Ig2_Robocd057249.1e-09229310
Ig2_FGFR_likecd057291.7e-12229310
Ig2_FGFRL1-likecd058569.6e-08229310
Ig_Myomesin_like_Ccd057370.00037233310
Ig2_FGFRcd058574.7e-06234310
Ig3_L1-CAMcd058760.00014235311
Ig3_Peroxidasincd057454.1e-11238310
Ig5_Contactin_likecd049696.7e-07239310
Ig4_L1-NrCAM_likecd049780.00017239311
Ig_3cd057650.00082239310
Ig5_Contactin-1cd058520.00031239310
Ig6_Contactin_likecd049700.00068240314
Ig4_Neogenincd057231.5e-14241310
Ig_Titin_likecd057487.6e-07241312
Ig_2cd057640.0002241310
Igcd000962.3e-13242307
Ig3_FGFRcd049740.00033242311
Ig3_L1-CAM_likecd057311.6e-07242311
Ig2_Follistatin_likecd057360.00016242313
Ig4_Peroxidasincd057462.4e-10242309
Ig2_PTK7cd057603.4e-05242315
Ig_1cd057636.9e-07242311
Ig3_Robocd057259.3e-39242310
Ig_Pro_neuregulincd057503.8e-05244308
Ig5_NCAM-1_likecd057320.00075312408
Ig3_Contactin_likecd049685.3e-06313409
Ig3_Contactin-1cd058510.00024313409
Ig1_Neogenincd057220.00028315408
Ig4_Contactin-2-likecd057282e-06315408
Ig3_Perlecan_likecd057540.00057315407
Ig2_Robocd057241.1e-06318408
Ig2_FGFR_likecd057292.5e-05320408
Ig2_FGFRL1-likecd058560.00036322408
Ig3_Peroxidasincd057453.2e-13327408
Ig5_Contactin_likecd049691.1e-09328408
Ig4_L1-NrCAM_likecd049783.1e-05328409
Ig4_Robocd057264.4e-63328417
Ig_CEACAM_D1_likecd057410.00061328408
Ig_Perlecan_D2_likecd057438.5e-05328408
Ig_2cd057640.00058328408
Ig_3cd057651.1e-10328408
Ig4_Neogenincd057230.00012330408
Igcd000961.3e-11331409
Ig2_RPTP_IIa_LAR_likcd057380.00061331409
Ig4_Peroxidasincd057463.6e-06331407
Ig_1cd057633.1e-10331409
Ig3_Robocd057251.1e-08331408
Ig3_NCAM-1_likecd057307.1e-05416508
Ig3_Contactin_likecd049689.4e-07417506
Ig1_Robocd076935.5e-07417506
Ig_TrkABC_d4cd049724.6e-07418505
Ig5_NCAM-1_likecd057324.9e-06418505
Ig5_NCAM-2cd058703.9e-06418505
Ig4_Contactin-2-likecd057283e-06421505
Ig2_Robocd057241.5e-09422505
Ig2_FGFR_likecd057292.7e-07426505
Ig2_FGFRL1-likecd058561.6e-07426505
Ig2_FGFRcd058570.0002426505
Ig5_Contactin_likecd049692.8e-10432505
Ig4_L1-NrCAM_likecd049780.00028432506
Ig4_Robocd057266.1e-05432514
Ig3_Peroxidasincd057454.4e-08432505
Ig5_Contactin-1cd058521.3e-05432505
Ig4_Neogenincd057230.00014434505
Ig_2cd057641.8e-07434505
Igcd000961.5e-14435502
Ig6_L1-CAM_likecd057330.00062435506
Ig2_Follistatin_likecd057367.1e-10435508
Ig2_RPTP_IIa_LAR_likcd057387.4e-05435506
Ig4_Peroxidasincd057462.5e-10435504
Ig_Pro_neuregulincd057500.00059435503
Ig_1cd057632.1e-10435506
Ig3_Robocd057255e-12435505
FN3cd000633.9e-24522615
FN3cd000633.3e-14635731
FN3cd000633.1e-17736833
igpfam000470.00017147205
igpfam000477.2e-10239295
igpfam000477.1e-10328393
igpfam000471.4e-07432490
fn3pfam000411.6e-16523607
fn3pfam000410.00035636724
fn3pfam000412.6e-14738826
I-setpfam076792.1e-1631128
IGsmart004094.4e-1537129
IG_likesmart004104.4e-1537129
IGc2smart004083.6e-1244117
I-setpfam076791.2e-11133221
IGsmart004099.7e-17139222
IG_likesmart004109.7e-17139222
IGc2smart004088.8e-11146210
I-setpfam076791.4e-32225310
IGsmart004098.9e-18231311
IG_likesmart004108.9e-18231311
IGc2smart004086.7e-12238300
I-setpfam076791.4e-17314408
IGsmart004091.1e-19320409
IG_likesmart004101.1e-19320409
V-setpfam076862.7e-06322408
IGc2smart004081.9e-10327398
I-setpfam076791.4e-17418505
IGsmart004091.2e-19424506
IG_likesmart004101.2e-19424506
V-setpfam076868.8e-06426507
IGc2smart004089.2e-14431495
FN3smart000608.6e-20522604
FN3smart000605.2e-08636721
FN3smart000602.8e-12740823

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_032961Diseasep.ALA1236THRVesicoureteral reflux 2 (VUR2)
Swiss-ProtVAR_032960Diseasep.ILE945THRVesicoureteral reflux 2 (VUR2)
OMIM602431.0002 Diseasep.ALA1255THRVESICOURETERAL REFLUX 2
OMIM602431.0001 Diseasep.ILE964THRVESICOURETERAL REFLUX 2



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