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Results for the Protein: P35568
547738

IRS1_HUMAN RecName: Full=Insulin receptor substrate 1; Short=IRS-1

Known Diseases associated with this Protein:
  CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO, INCLUDED
  DIABETES MELLITUS, NON-INSULIN-DEPENDENT (NIDDM)
  DIABETES MELLITUS, TYPE II
  INSULIN RESISTANCE, SUSCEPTIBILITY TO
4
10
2
3
9
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Default View:

PH - smart00233
PTBI - smart00310


Swiss-Prot Protein: P35568
Identical to: NP_005535
   Default View:



Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
PHsmart002335.2e-1313115
PTBIsmart003107.3e-61161262

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
dbSNPrs1801276 Polymorphismp.ALA512PRON/A
Swiss-ProtVAR_021837Polymorphismp.ASP1137ASNN/A
Swiss-ProtVAR_005303Diseasep.CYS1095TYRDiabetes mellitus, non-insulin-dependent (NIDDM)
Swiss-ProtVAR_005300Polymorphismp.GLY971ARGN/A
dbSNPrs1801278 Polymorphismp.GLY971TRPN/A
Swiss-ProtVAR_014854Polymorphismp.MET209THRN/A
Swiss-ProtVAR_014853Polymorphismp.PRO158ARGN/A
Swiss-ProtVAR_014856Polymorphismp.SER892GLYN/A
dbSNPrs12999226 Polymorphismp.SER1035PHEN/A
Swiss-ProtVAR_014855Polymorphismp.SER809PHEN/A
Swiss-ProtVAR_005302Diseasep.SER1043TYRDiabetes mellitus, non-insulin-dependent (NIDDM)
Swiss-ProtVAR_025320Polymorphismp.THR608ARGN/A
OMIM147545.0002 Diseasep.GLY972ARGINSULIN RESISTANCE, SUSCEPTIBILITY TO||CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO, INCLUDED
OMIM147545.0003 Diseasep.THR608ARGDIABETES MELLITUS, TYPE II



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