Results for the protein: Q9H422

Results for the Protein: Q9H422

61213741

10114

HIPK3

NCBI, UniProt

HIPK3_HUMAN RecName: Full=Homeodomain-interacting protein kinase 3; AltName: Full=Androgen receptor-interacting nuclear protein kinase; Short=ANPK; AltName: Full=Fas-interacting serine/threonine-protein kinase; Short=FIST; AltName: Full=Homolog of protein kinase YAK1

			0 6 0 2 4

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Swiss-Prot Protein: Q9H422

Identical to: NP_005725

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_TAO1	cd06635	7e-05	165	508
STKc_JNK1	cd07875	2.6e-08	175	568
STKc_PAK1	cd06654	0.00024	176	478
STKc_PAK6	cd06659	0.00077	176	480
STKc_JNK2	cd07876	3.1e-09	176	559
STKc_TAO3	cd06633	0.00061	178	491
STKc_myosinIIIB	cd06639	0.00029	178	465
STKc_PAK	cd06614	5.7e-09	180	462
STKc_JNK	cd07850	1.2e-12	180	564
STKc_TAO2	cd06634	0.00011	181	509
STKc_PAK_II	cd06648	0.00033	181	471
PKc_MKK7	cd06618	1.9e-05	182	483
STKc_STK10_LOK	cd06644	3.2e-05	182	474
STKc_p38	cd07851	6.2e-15	182	563
STKc_JNK3	cd07874	4.8e-09	182	572
STKc_p38alpha_MAPK14	cd07877	1.1e-10	182	569
STKc_p38beta_MAPK11	cd07878	1.1e-09	182	562
STKc_p38gamma_MAPK12	cd07880	4.4e-11	182	569
STKc_myosinIIIA	cd06638	0.00013	183	454
STKc_MAP4K4_6	cd06636	0.00041	183	463
STKc_CDK9	cd07865	1e-11	183	525
STKc_p38delta_MAPK13	cd07879	3e-06	184	569
STKc_TAO	cd06607	4.8e-05	185	469
STKc_MAPK15	cd07852	7.5e-12	185	546
STKc_PAK_I	cd06647	0.00071	186	475
STKc_PAK3	cd06656	0.0003	186	472
STKc_ASK	cd06624	0.00011	187	454
PTKc_Chk	cd05083	0.00075	189	455
STKc_CDK10	cd07845	7.2e-12	189	534
STKc_Sty1_Hog1	cd07856	1.6e-10	189	550
STKc_myosinIII_like	cd06608	4.2e-07	190	408
STKc_TNIK	cd06637	5.4e-05	190	463
PTKc_Ror	cd05048	0.00011	191	449
PTKc_Abl	cd05052	7.3e-05	191	459
STKc_SLK	cd06643	2.8e-05	191	472
STKc_CDC2L1	cd07843	2.3e-12	191	525
STKc_PCTAIRE_like	cd07844	8.2e-14	191	488
STKc_ERK1_2_like	cd07849	1.4e-12	191	572
STKc_MAPK4_6	cd07854	6.4e-09	191	568
STKc_TEY_MAPK_plant	cd07858	2.6e-15	191	569
STKc_BUR1	cd07866	1e-10	191	525
STKc_PFTAIRE1	cd07869	4.4e-05	191	494
STKc_PCTAIRE3	cd07871	9.6e-09	191	488
STKc_PFTAIRE2	cd07870	2e-06	191	485
PTKc_TrkA	cd05092	0.00025	192	473
STKc_LATS	cd05598	0.001	192	524
STKc_MST4	cd06640	0.00012	192	478
STKc_MST3	cd06641	0.00032	192	478
STKc_STK25-YSK1	cd06642	3.9e-05	192	478
STKc_ERK5	cd07855	4.4e-11	192	552
PTKc_InsR_like	cd05032	0.00074	193	451
PTKc_Frk_like	cd05068	3.7e-06	193	452
PTKc_Tyk2_rpt2	cd05080	0.00088	193	476
PTKc_Lyn	cd05072	0.00057	193	474
PTKc_Itk	cd05112	0.00036	193	450
PTKc_Btk_Bmx	cd05113	3.7e-05	193	462
PTKc_Fyn_Yrk	cd05070	0.00047	193	452
STKc_MST1_2	cd06612	1.8e-08	193	425
STKc_MAP4K3_like	cd06613	1.6e-07	193	454
PKc_MAPKK_Byr1_like	cd06620	2.6e-05	193	537
PTKc_Src_like	cd05034	8.9e-06	194	474
PTKc_ALK_LTK	cd05036	7.7e-06	194	454
PTKc_Trk	cd05049	2.5e-05	194	451
PTKc_Musk	cd05050	9.3e-05	194	452
PTKc_EphR_A10	cd05064	0.00062	194	459
PTKc_Srm_Brk	cd05148	0.00028	194	425
STKc_SLK_like	cd06611	0.00074	194	470
STKc_MEKK3_like_1	cd06653	4.5e-05	194	455
STKc_Nek6_Nek7	cd08224	4.7e-05	194	460
PTKc_Jak_rpt2	cd05038	4.8e-05	195	441
PTKc_Ror1	cd05090	0.00086	195	444
PTKc_Tec_Rlk	cd05114	0.00023	195	450
STKc_phototropin_lik	cd05574	8.2e-06	195	428
STKc_PKA	cd05580	4.1e-08	195	462
STKc_PDK1	cd05581	3.1e-14	195	433
STKc_ROCK_NDR_like	cd05573	4.3e-06	195	504
STKc_DMPK_like	cd05597	6.6e-05	195	530
STKc_Sid2p_Dbf2p	cd05600	0.00087	195	499
STKc_CRIK	cd05601	3e-05	195	467
STKc_NDR_like	cd05599	0.00029	195	484
STKc_PRKX_like	cd05612	0.0001	195	472
STKc_MAST	cd05609	6.8e-07	195	509
STKc_MRCK_beta	cd05624	0.00063	195	515
STKc_NDR2	cd05627	0.00069	195	533
STKc_NDR1	cd05628	0.00018	195	518
STKc_MRCK_alpha	cd05623	0.00055	195	505
PKc_MAPKK	cd06605	1.9e-07	195	439
STKc_MST3_like	cd06609	1.9e-07	195	445
STKc_OSR1_SPAK	cd06610	6.2e-06	195	433
PKc_MEK	cd06615	4.1e-06	195	543
PKc_MKK3_6	cd06617	3.5e-07	195	472
PKc_MKK5	cd06619	0.00036	195	492
PKc_MAPKK_Pek1_like	cd06621	0.00056	195	468
PKc_MAPKK_PBS2_like	cd06622	5.7e-06	195	509
PKc_MAPKK_plant_like	cd06623	4.3e-08	195	460
STKc_MEKK3_like	cd06625	1.2e-06	195	454
STKc_NAK1_like	cd06917	8.2e-08	195	479
STKc_CDKL	cd07833	8.5e-17	195	525
STKc_CdkB_plant	cd07837	2.2e-13	195	526
STKc_CDKL2_3	cd07846	3.4e-15	195	525
STKc_CDKL5	cd07848	4.8e-16	195	525
STKc_CDK6	cd07862	1.6e-07	195	476
STKc_CDK12	cd07864	1.2e-10	195	525
STKc_PCTAIRE2	cd07872	1.3e-07	195	484
STKc_PCTAIRE1	cd07873	1.8e-08	195	511
STKc_CDKL1_4	cd07847	3e-29	195	507
STKc_Nek7	cd08229	3.1e-05	195	451
STKc_Nek6	cd08228	0.00033	195	460
SPS1	COG0515	1.4e-45	195	693
PKc_STE	cd05122	2.5e-12	196	524
STKc_Yank1	cd05578	4e-07	196	452
STKc_MSK_N	cd05583	4.5e-05	196	474
STKc_GRK4_like	cd05605	1.3e-06	196	495
STKc_MSK2_N	cd05614	0.00025	196	527
STKc_cPKC_beta	cd05616	2.2e-06	196	526
STKc_cPKC_alpha	cd05615	9.6e-07	196	526
STKc_cPKC	cd05587	1.1e-07	196	526
STKc_GRK4	cd05631	0.00032	196	479
STKc_GRK5	cd05632	0.00011	196	483
STKc_MAPKKK	cd06606	6.7e-14	196	433
STKc_MAPKKK_Byr2_lik	cd06628	7e-06	196	458
STKc_YSK4	cd06631	1.8e-05	196	463
STKc_Cdc7_like	cd06627	1.5e-10	196	425
STKc_MEKK3	cd06651	3.8e-06	196	456
STKc_CCRK	cd07832	5.7e-15	196	526
STKc_Pho85	cd07836	1.4e-18	196	494
STKc_MAPK	cd07834	1.1e-14	196	585
STKc_CDK5	cd07839	8.5e-10	196	469
STKc_CDK7	cd07841	3.3e-13	196	534
STKc_CDK8_like	cd07842	3.9e-11	196	525
STKc_NLK	cd07853	1.8e-07	196	605
STKc_MPK1	cd07857	8.3e-10	196	570
STKc_TDY_MAPK_plant	cd07859	2e-10	196	534
STKc_CDK2_3	cd07860	6.3e-14	196	525
STKc_CDK1_euk	cd07861	2.3e-15	196	525
STKc_CDC2L6	cd07867	3e-06	196	525
STKc_CDK8	cd07868	3.2e-06	196	525
STKc_CDK4	cd07863	9.1e-14	196	479
STKc_Nek	cd08215	3.5e-10	196	417
STKc_Nek2	cd08217	3.4e-08	196	428
STKc_Nek1	cd08218	9.3e-05	196	455
STKc_Nek3	cd08219	5.9e-09	196	452
STKc_Nek8	cd08220	8.8e-06	196	444
STKc_Nek9	cd08221	8e-06	196	446
STKc_Nek4	cd08223	0.00094	196	452
STKc_Nek5	cd08225	0.00026	196	449
STKc_Nek10	cd08528	4.2e-06	196	442
STKc_FA2-like	cd08529	3e-06	196	428
STKc_CNK2-like	cd08530	9.2e-07	196	428
PTKc_Yes	cd05069	0.00024	197	452
STKc_CMGC	cd05118	1.5e-30	197	525
STKc_PKN	cd05589	1.5e-05	197	501
STKc_CDK_like	cd07829	3.3e-21	197	525
STKc_MAK_like	cd07830	7.5e-22	197	525
STKc_MOK	cd07831	1.8e-17	197	525
STKc_CDK1_like	cd07835	8.3e-16	197	488
STKc_CDK4_6_like	cd07838	2e-14	197	525
STKc_CDK9_like	cd07840	8.3e-15	197	525
PTKc_Jak2_Jak3_rpt2	cd05081	6.9e-06	198	481
STKc_RSK_N	cd05582	0.00086	200	530
STKc_p70S6K	cd05584	7.2e-06	200	532
STKc_MEKK4	cd06626	4.1e-09	200	425
PTKc	cd00192	2.8e-05	201	441
PTKc_Ack_like	cd05040	4.5e-05	201	424
PTKc_Syk	cd05116	0.00027	201	468
STKc_PKC	cd05570	1.6e-07	201	525
STKc_PKB	cd05571	4.1e-06	201	538
STKc_SGK	cd05575	0.0005	201	525
STKc_aPKC	cd05588	3.2e-05	201	526
STKc_nPKC_eta	cd05590	0.00015	201	537
STKc_nPKC_epsilon	cd05591	8.4e-07	201	503
STKc_nPKC_theta_delt	cd05592	1.1e-06	201	527
STKc_PKB_alpha	cd05594	8.4e-05	201	542
STKc_PKB_beta	cd05595	0.001	201	538
STKc_SGK2	cd05603	3.4e-05	201	537
STKc_PKB_gamma	cd05593	0.00023	201	541
STKc_aPKC_zeta	cd05617	0.00021	201	526
STKc_nPKC_theta	cd05619	3.4e-06	201	504
STKc_nPKC_delta	cd05620	0.0008	201	504
STKc_MAPKKK_Bck1_lik	cd06629	8.1e-06	201	444
STKc_MEKK1	cd06630	0.00019	201	456
STKc_beta_ARK	cd05606	2.1e-05	202	473
STKc_GRK3	cd05633	0.00045	202	474
STKc_MEKK1_plant	cd06632	9.4e-08	202	425
PKc	cd00180	7.1e-57	203	523
PTKc_Tec_like	cd05059	0.00061	203	427
PTKc_Syk_like	cd05060	2.7e-05	203	428
PTKc_Zap-70	cd05115	0.00073	203	466
STKc_AGC	cd05123	6e-12	203	433
STKc_cGK_PKG	cd05572	9.1e-08	203	443
STKc_GRK	cd05577	6.2e-05	203	473
STKc_YPK1_like	cd05585	0.00013	203	529
STKc_MAST_like	cd05579	1.2e-09	203	438
STKc_Sck1_like	cd05586	0.00021	203	548
STKc_GRK7	cd05607	0.00033	203	491
STKc_GRK1	cd05608	0.00012	203	466
Pkinase	pfam00069	1.2e-43	197	525
Pkinase_Tyr	pfam07714	2.7e-10	197	433
TyrKc	smart00219	2.2e-07	197	467
STYKc	smart00221	3.3e-65	197	525
S_TKc	smart00220	3.9e-68	207	525

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040551	Polymorphism	p.CYS191ARG	N/A
Swiss-Prot	VAR_040549	Polymorphism	p.GLN142ARG	N/A
Swiss-Prot	VAR_040550	Polymorphism	p.GLY170GLU	N/A
Swiss-Prot	VAR_040553	Polymorphism	p.PRO729LEU	N/A
dbSNP	rs11032229	Polymorphism	p.SER500ASN	N/A
dbSNP	rs266472	Polymorphism	p.VAL474ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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