Results for the protein: Q9Y5S2

Results for the Protein: Q9Y5S2

92090617

9578

CDC42BPB

NCBI, UniProt

MRCKB_HUMAN RecName: Full=Serine/threonine-protein kinase MRCK beta; AltName: Full=CDC42-binding protein kinase beta; Short=CDC42BP-beta; AltName: Full=DMPK-like beta; AltName: Full=Myotonic dystrophy kinase-related CDC42-binding kinase beta; Short=MRCK beta; Short=Myotonic dystrophy protein kinase-like beta

			0 8 0 1 7

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Swiss-Prot Protein: Q9Y5S2

Identical to: NP_006026

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK2	cd05621	3.3e-140	32	405
STKc_ROCK1	cd05622	4.8e-145	32	406
STKc_PAK_I	cd06647	2.5e-07	53	368
STKc_PAK1	cd06654	2.9e-07	53	370
STKc_PAK3	cd06656	5.4e-08	53	363
STKc_myosinIIIA	cd06638	7e-09	55	342
STKc_TAO	cd06607	6.1e-05	56	361
STKc_myosinIIIB	cd06639	1.1e-07	56	343
STKc_PAK_II	cd06648	7.8e-11	57	354
STKc_PAK2	cd06655	4.6e-07	57	369
STKc_PAK4	cd06657	7.2e-07	57	351
STKc_PAK6	cd06659	1.6e-09	57	368
STKc_PAK5	cd06658	8.7e-07	57	354
STKc_p38alpha_MAPK14	cd07877	0.00018	59	400
STKc_PAK	cd06614	1.7e-13	60	331
STKc_TAO1	cd06635	5.1e-05	61	379
STKc_STK10_LOK	cd06644	7.2e-09	62	361
STKc_p38beta_MAPK11	cd07878	8.4e-05	62	428
STKc_p38gamma_MAPK12	cd07880	3.2e-06	62	400
PTKc_HER4	cd05110	0.00094	63	355
PTK_HER3	cd05111	0.00047	63	351
STKc_p38	cd07851	2.7e-07	63	385
STKc_CDK9	cd07865	4.4e-07	63	342
STKc_MAP4K4_6	cd06636	5.2e-06	64	342
PKc_MKK7	cd06618	5.7e-10	64	348
STKc_JNK	cd07850	0.00023	65	383
STKc_TAO2	cd06634	0.0002	66	360
STKc_MAPK15	cd07852	6.6e-07	66	382
STKc_ASK	cd06624	7.6e-09	67	342
STKc_MAP4K5	cd06646	8.7e-07	68	341
PTKc_ALK_LTK	cd05036	4.1e-06	69	315
PTKc_Abl	cd05052	2.3e-06	69	346
PTKc_Lck_Blk	cd05067	0.00056	69	336
PTKc_Frk_like	cd05068	2.2e-05	69	336
PTKc_Fyn_Yrk	cd05070	8e-05	69	336
PTKc_Yes	cd05069	2.6e-05	69	336
PTKc_Src	cd05071	0.00022	69	342
PTKc_Lyn	cd05072	3.6e-06	69	336
PTKc_Hck	cd05073	8.7e-06	69	336
PTKc_FAK	cd05056	1.4e-06	69	332
STKc_TNIK	cd06637	5e-07	69	342
STKc_ERK5	cd07855	2.3e-05	69	380
STKc_TEY_MAPK_plant	cd07858	1.2e-06	69	385
STKc_CDK12	cd07864	1.4e-07	69	333
PTKc_Trk	cd05049	3.1e-06	70	338
PTKc_Musk	cd05050	4.4e-05	70	330
PTKc_EphR_A10	cd05064	2.3e-05	70	341
PTKc_TrkB	cd05093	0.00028	70	354
PTKc_TrkA	cd05092	2.6e-05	70	343
PTKc_Tie2	cd05088	0.0003	70	352
PTKc_EphR_A2	cd05063	0.0001	70	341
PKc_MAPKK_Byr1_like	cd06620	6.9e-11	70	340
STKc_MAP4K3	cd06645	1e-07	70	341
PKc_MEK2	cd06649	9.1e-07	70	425
PKc_MEK1	cd06650	1e-05	70	429
PTKc_EphR	cd05033	0.00041	71	317
PTKc_InsR_like	cd05032	4e-06	71	322
PTKc_Jak_rpt2	cd05038	3.3e-06	71	340
PTKc_Src_like	cd05034	1.6e-05	71	336
PTKc_EphR_A	cd05066	0.00015	71	341
PTKc_Jak1_rpt2	cd05079	0.00056	71	340
PTKc_Tyk2_rpt2	cd05080	0.00097	71	341
PTKc_Tec_like	cd05059	2.3e-05	71	310
PTKc_EGFR	cd05108	0.00052	71	385
PTKc_Itk	cd05112	1.3e-05	71	325
PTKc_Tec_Rlk	cd05114	2.5e-07	71	341
PTKc_Btk_Bmx	cd05113	1.1e-06	71	325
PTKc_EphR_B	cd05065	0.00055	71	341
PTKc_Srm_Brk	cd05148	6.6e-05	71	312
PKc_MKK4	cd06616	1.1e-08	71	362
STKc_SLK	cd06643	8e-10	71	359
STKc_MAP4K3_like	cd06613	1.9e-12	72	341
STKc_PCTAIRE_like	cd07844	2.4e-07	72	358
STKc_BUR1	cd07866	2.6e-08	72	342
STKc_PFTAIRE1	cd07869	0.00037	72	351
STKc_PCTAIRE3	cd07871	1.8e-06	72	342
STKc_PCTAIRE1	cd07873	4.1e-06	72	355
STKc_PCTAIRE2	cd07872	1.5e-05	72	362
STKc_PFTAIRE2	cd07870	5.3e-05	72	358
STKc_SLK_like	cd06611	1.2e-09	73	356
STKc_MST4	cd06640	3.5e-08	73	348
STKc_MST3	cd06641	1e-07	73	343
STKc_MEKK2	cd06652	3.6e-07	73	343
STKc_MEKK3_like_1	cd06653	1.4e-08	73	342
STKc_STK25-YSK1	cd06642	2.3e-08	73	353
STKc_ERK1_2_like	cd07849	5.8e-06	73	384
STKc_Nek6_Nek7	cd08224	4.4e-10	73	342
PTKc_Tie1	cd05089	0.00041	74	351
STKc_phototropin_lik	cd05574	8.5e-53	74	366
STKc_PKA	cd05580	1.7e-75	74	373
STKc_PDK1	cd05581	1.9e-59	74	342
STKc_ROCK_NDR_like	cd05573	7.8e-195	74	404
STKc_DMPK_like	cd05597	9e-252	74	404
STKc_LATS	cd05598	1.6e-91	74	409
STKc_Sid2p_Dbf2p	cd05600	3.8e-62	74	405
STKc_CRIK	cd05601	8.1e-148	74	404
STKc_NDR_like	cd05599	7.2e-119	74	407
STKc_MAST	cd05609	9.1e-62	74	371
STKc_PRKX_like	cd05612	1.3e-70	74	374
STKc_MASTL	cd05610	2.3e-05	74	714
STKc_MRCK_alpha	cd05623	1.7e-278	74	405
STKc_LATS2	cd05626	2.3e-75	74	409
STKc_NDR2	cd05627	7.3e-99	74	428
STKc_MRCK_beta	cd05624		74	404
STKc_NDR1	cd05628	1.3e-98	74	407
STKc_NDR_like_fungal	cd05629	6.6e-101	74	407
PKc_MAPKK	cd06605	2.4e-11	74	347
STKc_MST3_like	cd06609	6.1e-13	74	340
STKc_OSR1_SPAK	cd06610	7.7e-13	74	342
PKc_MEK	cd06615	1e-11	74	419
STKc_MST1_2	cd06612	2.1e-13	74	342
PKc_MKK3_6	cd06617	3.2e-08	74	322
PKc_MKK5	cd06619	0.00016	74	357
PKc_MAPKK_Pek1_like	cd06621	3e-08	74	341
PKc_MAPKK_plant_like	cd06623	1.3e-16	74	335
PKc_MAPKK_PBS2_like	cd06622	1.7e-07	74	380
STKc_myosinIII_like	cd06608	3.7e-11	74	342
STKc_NAK1_like	cd06917	5.3e-11	74	321
STKc_CDKL	cd07833	6.1e-10	74	342
STKc_CdkB_plant	cd07837	5.7e-09	74	343
STKc_CDC2L1	cd07843	5.4e-08	74	342
STKc_CDK10	cd07845	3.8e-06	74	359
STKc_CDKL2_3	cd07846	3.9e-09	74	342
STKc_CDKL1_4	cd07847	2.4e-13	74	358
STKc_CDKL5	cd07848	8.1e-07	74	342
STKc_CDK6	cd07862	6.1e-05	74	358
STKc_Nek6	cd08228	8.7e-10	74	342
STKc_Nek7	cd08229	1.4e-11	74	342
SPS1	COG0515	5.5e-50	74	509
PKc_STE	cd05122	3.3e-26	75	341
STKc_Yank1	cd05578	2.1e-66	75	342
STKc_MSK_N	cd05583	3.2e-69	75	359
STKc_GRK4_like	cd05605	1.3e-37	75	361
STKc_MSK1_N	cd05613	5.8e-54	75	359
STKc_MSK2_N	cd05614	9e-60	75	406
STKc_cPKC_alpha	cd05615	2.1e-45	75	405
STKc_cPKC_beta	cd05616	1.4e-49	75	405
STKc_cPKC	cd05587	4.7e-59	75	405
STKc_GRK6	cd05630	6.9e-33	75	361
STKc_GRK4	cd05631	7.6e-33	75	361
STKc_GRK5	cd05632	1.2e-31	75	361
STKc_MAPKKK	cd06606	2.2e-37	75	342
STKc_Cdc7_like	cd06627	3.8e-15	75	342
STKc_MEKK3	cd06651	7.2e-11	75	344
STKc_CCRK	cd07832	4.3e-14	75	343
STKc_CDK5	cd07839	4.1e-07	75	342
STKc_CDK7	cd07841	6e-09	75	329
STKc_CDK8_like	cd07842	3.7e-05	75	342
STKc_NLK	cd07853	6.5e-06	75	427
STKc_MPK1	cd07857	1.5e-06	75	361
STKc_CDK1_euk	cd07861	4.7e-07	75	358
STKc_CDK4	cd07863	2.6e-05	75	358
STKc_CDK2_3	cd07860	1.1e-05	75	358
STKc_Pho85	cd07836	2.1e-05	75	358
STKc_MAPK	cd07834	5.4e-08	75	382
STKc_TDY_MAPK_plant	cd07859	1.1e-06	75	387
STKc_Nek	cd08215	1.3e-20	75	327
STKc_Nek2	cd08217	1.4e-15	75	322
STKc_Nek1	cd08218	1e-21	75	342
STKc_Nek3	cd08219	5.4e-24	75	333
STKc_Nek8	cd08220	1.1e-09	75	342
STKc_Nek11	cd08222	2.1e-07	75	341
STKc_Nek4	cd08223	9.4e-13	75	342
STKc_Nek5	cd08225	3.6e-21	75	342
STKc_Nek9	cd08221	2.6e-09	75	322
STKc_Nek10	cd08528	1.2e-07	75	335
STKc_FA2-like	cd08529	2.3e-14	75	333
STKc_CNK2-like	cd08530	3.9e-11	75	339
PTKc_Jak2_Jak3_rpt2	cd05081	4.6e-05	76	351
STKc_CMGC	cd05118	2e-13	76	342
STKc_PKN	cd05589	6.7e-60	76	404
STKc_LATS1	cd05625	1.3e-64	76	409
STKc_MAPKKK_Bck1_lik	cd06629	6.6e-07	76	342
STKc_CDK_like	cd07829	4e-14	76	342
STKc_MAK_like	cd07830	3.7e-09	76	342
STKc_MOK	cd07831	6.2e-10	76	342
STKc_CDK1_like	cd07835	3.1e-07	76	358
STKc_CDK4_6_like	cd07838	3.5e-09	76	342
STKc_CDK9_like	cd07840	3.1e-11	76	342
STKc_Sty1_Hog1	cd07856	0.00012	76	386
STKc_MAPKKK_Byr2_lik	cd06628	7.7e-09	77	342
PK_STRAD	cd08216	3.2e-05	77	356
PK_STRAD_alpha	cd08227	0.00013	77	402
STKc_RSK_N	cd05582	5.1e-61	79	404
STKc_p70S6K	cd05584	1.5e-65	79	406
STKc_Rim15_like	cd05611	1.3e-20	79	348
PTKc	cd00192	7.2e-10	80	337
PTKc_Ack_like	cd05040	9.1e-05	80	311
PTKc_c-ros	cd05044	2.2e-05	80	331
PTKc_Fes_like	cd05041	9.2e-09	80	312
PTKc_Syk_like	cd05060	8.9e-05	80	318
PTKc_Fes	cd05084	1e-05	80	340
PTKc_Fer	cd05085	1.8e-05	80	318
PTKc_Syk	cd05116	1.9e-05	80	342
STKc_PKB	cd05571	1.3e-63	80	406
STKc_SGK	cd05575	1.9e-69	80	404
STKc_aPKC	cd05588	2.7e-46	80	405
STKc_nPKC_eta	cd05590	1.6e-60	80	405
STKc_PKC	cd05570	1.7e-50	80	404
STKc_nPKC_theta_delt	cd05592	8.9e-62	80	406
STKc_PKB_gamma	cd05593	2.2e-44	80	407
STKc_PKB_alpha	cd05594	1.9e-50	80	407
STKc_nPKC_epsilon	cd05591	1e-58	80	405
STKc_PKB_beta	cd05595	4.1e-53	80	406
STKc_SGK1	cd05602	1.9e-53	80	406
STKc_SGK2	cd05603	1e-54	80	405
STKc_SGK3	cd05604	1.1e-54	80	406
STKc_aPKC_zeta	cd05617	1.2e-33	80	405
STKc_aPKC_iota	cd05618	1.8e-35	80	395
STKc_nPKC_theta	cd05619	9.8e-50	80	406
STKc_nPKC_delta	cd05620	7.2e-46	80	406
STKc_MEKK3_like	cd06625	8.8e-14	80	342
STKc_MEKK1	cd06630	2.1e-08	80	343
STKc_YSK4	cd06631	1.2e-08	80	342
STKc_MEKK1_plant	cd06632	1.2e-09	80	342
STKc_MEKK4	cd06626	8.2e-12	80	342
STKc_beta_ARK	cd05606	7.2e-37	81	360
STKc_GRK3	cd05633	2.5e-28	81	361
PKc	cd00180	1.5e-63	82	340
PTKc_Zap-70	cd05115	4.8e-06	82	342
STKc_AGC	cd05123	1.1e-109	82	342
STKc_cGK_PKG	cd05572	7.9e-59	82	349
STKc_GRK	cd05577	4.2e-39	82	360
STKc_MAST_like	cd05579	2.4e-75	82	347
STKc_YPK1_like	cd05585	5e-69	82	403
STKc_Sck1_like	cd05586	8e-57	82	447
STKc_GRK7	cd05607	1.2e-37	82	360
STKc_GRK1	cd05608	2.7e-38	82	360
C1	cd00029	6.1e-15	1026	1075
PH_MRCK	cd01243	7.2e-74	1095	1216
PH	cd00821	4.4e-05	1098	1212
PH-like	cd00900	0.00021	1098	1212
CRIB	cd00132	2.7e-09	1581	1623
Pkinase	pfam00069	3.7e-59	76	342
Pkinase_C	pfam00433	3.9e-09	360	407
C1_1	pfam00130	1.5e-14	1026	1078
CNH	pfam00780	5.3e-93	1245	1510
Pkinase_Tyr	pfam07714	1.1e-13	76	320
STYKc	smart00221	1.5e-78	76	342
TyrKc	smart00219	1.4e-11	76	337
S_TKc	smart00220	2.8e-88	86	342
S_TK_X	smart00133	5.6e-12	343	405
DMPK_coil	pfam08826	2.1e-31	878	939
C1	smart00109	3.1e-12	1026	1075
PH	smart00233	4e-06	1096	1214
CNH	smart00036	6.4e-11	1240	1529
PBD	smart00285	2.4e-09	1583	1618

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040835	Polymorphism	p.ARG555GLN	N/A
Swiss-Prot	VAR_040836	Polymorphism	p.ARG671GLN	N/A
Swiss-Prot	VAR_040837	Polymorphism	p.ARG876TRP	N/A
dbSNP	rs61745673	Polymorphism	p.ASP1485ASN	N/A
Swiss-Prot	VAR_040838	Polymorphism	p.GLU1315LYS	N/A
Swiss-Prot	VAR_025847	Polymorphism	p.ILE1077VAL	N/A
Swiss-Prot	VAR_040834	Polymorphism	p.LYS500GLU	N/A
Swiss-Prot	VAR_040839	Polymorphism	p.SER1633TYR	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258