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  Domain Name: 7TM_GPCR_Srv
Serpentine type 7TM GPCR chemoreceptor Srv. Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srv is a member of the Srg superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.
No pairwise interactions found for the domain 7TM_GPCR_Srv

Total Mutations Found: 45
Total Disease Mutations Found: 29
This domain occurred 13 times on human genes (24 proteins).



  NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 1
  RETINITIS PIGMENTOSA 4
  RETINITIS PIGMENTOSA 4, AUTOSOMAL RECESSIVE
  RETINITIS PUNCTATA ALBESCENS, INCLUDED


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for 7TM_GPCR_Srv













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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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