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  Domain Name: E1_DerP2_DerF2
ML domain. ML domain - MD-2-related lipid recognition domain. This family consists of proteins from plants, animals and fungi, including dust mite allergen Der P 2. It has been implicate in lipid recognition, particularly in the recognition of pathogen related products. A mutation in Npc2 causes a rare form of Niemann-Pick type C2 disease.
No pairwise interactions found for the domain E1_DerP2_DerF2

Total Mutations Found: 8
Total Disease Mutations Found: 5
This domain occurred 3 times on human genes (6 proteins).



  NIEMANN-PICK DISEASE, TYPE C2


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for E1_DerP2_DerF2









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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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