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  Domain Name: MTHFR
Methylenetetrahydrofolate reductase. This family includes the 5,10-methylenetetrahydrofolate reductase EC: from bacteria and methylenetetrahydrofolate reductase EC: from eukaryotes. The structure for this domain is known to be a TIM barrel.
No pairwise interactions found for the domain MTHFR

Total Mutations Found: 4
Total Disease Mutations Found: 3
This domain occurred 1 times on human genes (2 proteins).


 If you've navigated here from a protein, hovering over a position on the weblogo will display the corresponding protein position for that domain position.

 The histograms below the weblogo indicate mutations found on the domain. Red is for disease (OMIM) and blue is for SNPs.

 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.

Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  

No Conserved Features/Sites Found for MTHFR

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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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