Home News About DMDM Database Statistics Research Publications Contact  

 
  Domain Name: RecA-like_NTPases
RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
No pairwise interactions are available for this conserved domain.

Total Mutations Found: 25
Total Disease Mutations Found: 14
This domain occurred 10 times on human genes (23 proteins).



  (1 FAMILY)
  BREAST CANCER, FAMILIAL
  BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
  BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 4
  FANCONI ANEMIA, COMPLEMENTATION GROUP O
  MIRROR MOVEMENTS 2, SUSCEPTIBILITY TO
  MITOCHONDRIAL COMPLEX V (ATP SYNTHASE) DEFICIENCY, NUCLEAR TYPE 4


Tips:
 If you've navigated here from a protein, hovering over a position on the weblogo will display the corresponding protein position for that domain position.

 The histograms below the weblogo indicate mutations found on the domain. Red is for disease (OMIM) and blue is for SNPs.

 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.



Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


Feature Name:Total Found:
ATP binding site
Walker A motif
Walker B motif


















Weblogos are Copyright (c) 2002 Regents of the University of California




Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

   |   1000 Hilltop Circle, Baltimore, MD 21250   |   Department of Biological Sciences   |   Phone: 410-455-2258