DS-Score_programs.tar.gz
    - Contains the programs required to run the DS-Score program. This includes the directory,
      "DS_library" containing all databases needed to run the DS-Score program including the 
      Cancer and Non-cancer mutation databases.

      
Instructions for running the DS-Score program
    - All programs require perl 5 or higher
    - All programs have a -d flag for specifying the directory in which the program is to run. This
      must be the directory containing the scripts and the DS_library directory.
    - Steps:
perl run_domain_positions_by position.pl -d [directory]
perl run_ds_score.pl -d [directory]

Instructions for creating a randomized dataset
    - As described in the paper, this method was applied 1000 times to each mutation set.
    - To create a random dataset, specify the directory and the mutation file you want to randomize:
perl randomize_mutation_set.pl -d [directory] -m [path and filename of mutation database]

