Results for the gene: MET

Results for Proteins associated with the Gene: MET

MET

4233

P08581 NP_001120972 NP_000236

NCBI

Known Diseases associated with this Protein:

HEPATOCELLULAR CARCINOMA (HCC)

HEPATOCELLULAR CARCINOMA, CHILDHOOD TYPE, SOMATIC

RENAL CELL CARCINOMA PAPILLARY (RCCP)

RENAL CELL CARCINOMA, PAPILLARY, 1

RENAL CELL CARCINOMA, PAPILLARY, 1, SOMATIC

			38 15 20 2 31

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

Clicking a check box on the left will display or hide the corresponding domain(s).

To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: P08581

Identical to: NP_000236

Default View:

RefSeq Protein: NP_001120972

Default View:

RefSeq Protein: NP_000236

Default View:

Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_000236	IPT_PCSR	cd00603	563	656	2.1e-25
NP_000236	IPT_plexin_repeat1	cd01180	563	656	6.8e-44
NP_000236	IPT	cd00102	657	740	7.8e-20
NP_000236	IPT_PCSR	cd00603	657	740	3.2e-25
NP_000236	IPT_plexin_repeat2	cd01179	657	740	1.2e-37
NP_000236	IPT_plexin_repeat1	cd01180	657	740	7.9e-07
NP_000236	IPT	cd00102	742	837	2.6e-10
NP_000236	IPT_PCSR	cd00603	742	837	1.2e-14
NP_000236	IPT_plexin_repeat3	cd01181	742	837	1.5e-44
NP_000236	IPT_PCSR	cd00603	839	935	0.00074
NP_000236	PTKc_VEGFR	cd05054	954	1344	6.3e-38
NP_000236	PTKc_PDGFR_alpha	cd05105	982	1343	5.8e-16
NP_000236	PTKc_PDGFR_beta	cd05107	982	1342	5.7e-17
NP_000236	STKc_ROCK2	cd05621	1035	1358	0.00049
NP_000236	PTKc_CSF-1R	cd05106	1037	1342	5.4e-21
NP_000236	STKc_TAO1	cd06635	1049	1365	0.00046
NP_000236	PTKc_Kit	cd05104	1051	1341	6.2e-18
NP_000236	STKc_MAP4K3	cd06645	1054	1338	0.00068
NP_000236	STKc_myosinIIIB	cd06639	1055	1340	4e-05
NP_000236	PTKc_FGFR1	cd05098	1056	1348	8.3e-46
NP_000236	PTKc_FGFR4	cd05099	1057	1362	4.5e-46
NP_000236	STKc_PAK5	cd06658	1057	1334	0.00087
NP_000236	STKc_PAK6	cd06659	1058	1363	0.00012
NP_000236	PTKc_FGFR2	cd05101	1059	1348	5.5e-43
NP_000236	STKc_TAO2	cd06634	1059	1366	0.00014
NP_000236	STKc_TAO	cd06607	1059	1365	0.00013
NP_000236	STKc_PAK_II	cd06648	1059	1344	1.1e-06
NP_000236	STKc_PAK_I	cd06647	1059	1360	1.4e-05
NP_000236	STKc_PAK1	cd06654	1059	1358	1.3e-05
NP_000236	STKc_PAK2	cd06655	1059	1359	3.3e-05
NP_000236	STKc_PAK3	cd06656	1059	1364	1.7e-05
NP_000236	STKc_PAK4	cd06657	1059	1336	0.00092
NP_000236	PTK_Tyk2_rpt1	cd05076	1060	1338	6e-05
NP_000236	STKc_PAK	cd06614	1060	1345	8.1e-11
NP_000236	STKc_myosinIIIA	cd06638	1060	1339	4.5e-07
NP_000236	PKc_MKK7	cd06618	1061	1371	1.9e-06
NP_000236	STKc_MAP4K4_6	cd06636	1061	1340	0.00038
NP_000236	PTKc_PDGFR	cd05055	1062	1341	2e-20
NP_000236	PTKc_FGFR3	cd05100	1063	1383	2.5e-43
NP_000236	STKc_STK10_LOK	cd06644	1066	1357	0.00013
NP_000236	PTKc_Tie2	cd05088	1068	1361	1.4e-43
NP_000236	PTKc_ALK_LTK	cd05036	1069	1339	5.5e-70
NP_000236	PTKc_EGFR_like	cd05057	1069	1353	5.1e-74
NP_000236	PTKc_Chk	cd05083	1069	1340	6.2e-55
NP_000236	STKc_ASK	cd06624	1069	1339	1.6e-06
NP_000236	PTKc_DDR	cd05051	1070	1339	1.1e-45
NP_000236	STKc_Sty1_Hog1	cd07856	1070	1389	0.00091
NP_000236	STKc_BUR1	cd07866	1070	1341	1.1e-09
NP_000236	PTKc_InsR_like	cd05032	1071	1339	2.2e-85
NP_000236	PTKc_EphR	cd05033	1071	1341	3.4e-60
NP_000236	PTK_Ryk	cd05043	1071	1344	7.4e-60
NP_000236	PTKc_Abl	cd05052	1071	1341	7.5e-70
NP_000236	PTKc_FAK	cd05056	1071	1345	9.7e-71
NP_000236	PTKc_Src_like	cd05034	1071	1340	1.1e-67
NP_000236	PTKc_Tec_like	cd05059	1071	1338	5.7e-60
NP_000236	PTKc_EphR_B	cd05065	1071	1341	1.4e-59
NP_000236	PTKc_EphR_A	cd05066	1071	1341	2.3e-60
NP_000236	PTKc_Lck_Blk	cd05067	1071	1340	3.8e-45
NP_000236	PTKc_Yes	cd05069	1071	1340	1.2e-37
NP_000236	PTKc_Fyn_Yrk	cd05070	1071	1340	1.7e-43
NP_000236	PTKc_Src	cd05071	1071	1342	5e-43
NP_000236	PTKc_Hck	cd05073	1071	1340	1.2e-46
NP_000236	PTKc_EphR_A2	cd05063	1071	1341	5.7e-55
NP_000236	PTKc_TrkA	cd05092	1071	1339	2.1e-46
NP_000236	PTKc_Itk	cd05112	1071	1338	9.8e-62
NP_000236	PTKc_Btk_Bmx	cd05113	1071	1338	3e-64
NP_000236	PTKc_Tec_Rlk	cd05114	1071	1338	3.3e-65
NP_000236	STKc_TNIK	cd06637	1071	1339	7.4e-05
NP_000236	STKc_PCTAIRE_like	cd07844	1071	1373	1.4e-05
NP_000236	STKc_TEY_MAPK_plant	cd07858	1071	1390	0.00033
NP_000236	STKc_PFTAIRE2	cd07870	1071	1356	6.4e-05
NP_000236	STKc_PCTAIRE3	cd07871	1071	1350	4.8e-05
NP_000236	STKc_PCTAIRE2	cd07872	1071	1360	3.1e-05
NP_000236	STKc_MST3	cd06641	1072	1360	1.2e-07
NP_000236	STKc_STK25-YSK1	cd06642	1072	1360	3e-08
NP_000236	STKc_MST4	cd06640	1072	1360	8e-07
NP_000236	STKc_CDK10	cd07845	1072	1366	1.1e-06
NP_000236	STKc_PCTAIRE1	cd07873	1072	1354	0.00015
NP_000236	SPS1	COG0515	1072	1390	9.7e-09
NP_000236	PTKc_InsR	cd05061	1073	1350	5.1e-58
NP_000236	PTKc_Ror1	cd05090	1073	1340	2.2e-41
NP_000236	PTKc_DDR1	cd05096	1073	1339	1.2e-40
NP_000236	PTKc_DDR2	cd05095	1073	1339	5.2e-45
NP_000236	PTKc_Csk_like	cd05039	1074	1340	1.2e-51
NP_000236	PTKc_IGF-1R	cd05062	1074	1339	2.1e-60
NP_000236	PTKc_EphR_A10	cd05064	1074	1341	5.6e-45
NP_000236	PTKc_Frk_like	cd05068	1074	1340	2.7e-67
NP_000236	PTKc_Lyn	cd05072	1074	1340	4.2e-48
NP_000236	PTKc_Csk	cd05082	1074	1340	5.1e-54
NP_000236	PTKc_Ror2	cd05091	1074	1340	6.2e-33
NP_000236	PTKc_VEGFR3	cd05102	1074	1344	2.1e-34
NP_000236	STKc_PKA	cd05580	1074	1344	3.7e-05
NP_000236	STKc_MAP4K3_like	cd06613	1074	1338	2.4e-08
NP_000236	STKc_MST1_2	cd06612	1074	1345	1.9e-11
NP_000236	PKc_MAPKK_plant_like	cd06623	1074	1339	3.9e-09
NP_000236	STKc_MAPK4_6	cd07854	1074	1390	0.00017
NP_000236	STKc_CDK12	cd07864	1074	1345	1e-06
NP_000236	PTKc_Jak_rpt2	cd05038	1075	1341	7.7e-60
NP_000236	PTK_HER3	cd05111	1075	1353	7.2e-48
NP_000236	PKc_MAPKK_PBS2_like	cd06622	1075	1390	0.001
NP_000236	STKc_MEKK3_like_1	cd06653	1075	1340	3.2e-05
NP_000236	STKc_MEKK3	cd06651	1075	1341	3.8e-07
NP_000236	PTKc_Jak1_rpt2	cd05079	1076	1341	6e-36
NP_000236	STKc_MAPKKK	cd06606	1076	1334	5.9e-19
NP_000236	STKc_MST3_like	cd06609	1076	1352	8.3e-08
NP_000236	STKc_ERK5	cd07855	1076	1382	0.00013
NP_000236	PTKc_TrkB	cd05093	1077	1343	8e-47
NP_000236	PTKc_TrkC	cd05094	1077	1351	5.1e-24
NP_000236	PTKc_EGFR	cd05108	1077	1383	5.1e-51
NP_000236	PTKc_HER2	cd05109	1077	1353	1.2e-57
NP_000236	PKc_STE	cd05122	1077	1333	2.6e-13
NP_000236	PTKc_HER4	cd05110	1077	1373	1e-50
NP_000236	STKc_GRK4_like	cd05605	1077	1381	1.9e-05
NP_000236	STKc_GRK4	cd05631	1077	1366	0.00019
NP_000236	STKc_GRK5	cd05632	1077	1366	0.0003
NP_000236	STKc_myosinIII_like	cd06608	1077	1337	1.2e-08
NP_000236	STKc_CDK9_like	cd07840	1077	1345	6.2e-10
NP_000236	STKc_NLK	cd07853	1077	1368	5.3e-05
NP_000236	STKc_CDK8_like	cd07842	1077	1341	7.7e-05
NP_000236	STKc_Nek4	cd08223	1077	1340	1.6e-05
NP_000236	STKc_Nek6_Nek7	cd08224	1077	1343	2.3e-07
NP_000236	PTKc_Axl_like	cd05035	1078	1341	3.3e-107
NP_000236	PTKc_RET	cd05045	1078	1344	1.9e-56
NP_000236	PTKc_Ror	cd05048	1078	1340	2e-48
NP_000236	PTKc_Trk	cd05049	1078	1339	7.8e-57
NP_000236	PTKc_Musk	cd05050	1078	1339	1.3e-49
NP_000236	PTKc_FGFR	cd05053	1078	1342	4.5e-67
NP_000236	PTKc_Tyro3	cd05074	1078	1341	5.1e-90
NP_000236	PTKc_Axl	cd05075	1078	1341	1.7e-80
NP_000236	PTKc_Jak2_Jak3_rpt2	cd05081	1078	1341	6.6e-41
NP_000236	PTKc_Tyk2_rpt2	cd05080	1078	1342	2.3e-23
NP_000236	PTKc_Tie1	cd05089	1078	1360	1.4e-46
NP_000236	PTKc_DDR_like	cd05097	1078	1339	3e-47
NP_000236	PTKc_VEGFR2	cd05103	1078	1344	1.4e-31
NP_000236	STKc_cPKC	cd05587	1078	1388	0.00057
NP_000236	STKc_PKN	cd05589	1078	1382	1.4e-06
NP_000236	STKc_PRKX_like	cd05612	1078	1380	2.1e-06
NP_000236	STKc_cPKC_beta	cd05616	1078	1388	0.00034
NP_000236	STKc_SLK_like	cd06611	1078	1347	6.5e-07
NP_000236	STKc_CDK1_like	cd07835	1078	1368	7.1e-07
NP_000236	STKc_TDY_MAPK_plant	cd07859	1078	1388	0.00078
NP_000236	STKc_CDK6	cd07862	1078	1373	0.00025
NP_000236	STKc_Nek3	cd08219	1078	1339	8.8e-09
NP_000236	STKc_Nek5	cd08225	1078	1339	1.8e-06
NP_000236	STKc_Nek6	cd08228	1078	1343	1.4e-06
NP_000236	STKc_Nek7	cd08229	1078	1339	8.6e-08
NP_000236	PTK_CCK4	cd05046	1079	1339	6.7e-46
NP_000236	PTKc_Srm_Brk	cd05148	1079	1340	1e-50
NP_000236	STKc_Yank1	cd05578	1079	1340	1.3e-07
NP_000236	STKc_PDK1	cd05581	1079	1341	3.3e-10
NP_000236	STKc_OSR1_SPAK	cd06610	1079	1340	1.2e-09
NP_000236	STKc_Cdc7_like	cd06627	1079	1334	8.5e-13
NP_000236	STKc_SLK	cd06643	1079	1354	1.7e-05
NP_000236	STKc_MEKK2	cd06652	1079	1340	0.00037
NP_000236	STKc_CCRK	cd07832	1079	1346	5.8e-07
NP_000236	STKc_Pho85	cd07836	1079	1357	8.6e-05
NP_000236	STKc_CDK7	cd07841	1079	1334	2.9e-09
NP_000236	STKc_CDKL1_4	cd07847	1079	1380	0.00082
NP_000236	STKc_CDK2_3	cd07860	1079	1368	1.1e-05
NP_000236	STKc_CDK4	cd07863	1079	1361	0.0002
NP_000236	STKc_CDK1_euk	cd07861	1079	1368	6.1e-05
NP_000236	PK_STRAD	cd08216	1079	1347	0.0004
NP_000236	STKc_Nek1	cd08218	1079	1339	0.00024
NP_000236	STKc_Nek9	cd08221	1079	1339	7.9e-06
NP_000236	STKc_CNK2-like	cd08530	1079	1339	1.4e-06
NP_000236	STKc_Nek10	cd08528	1079	1339	4.2e-07
NP_000236	STKc_MAPKKK_Bck1_lik	cd06629	1080	1308	1.9e-10
NP_000236	STKc_MAPK	cd07834	1080	1388	6e-06
NP_000236	STKc_CDK4_6_like	cd07838	1080	1341	1.4e-06
NP_000236	STKc_Nek11	cd08222	1080	1340	1.4e-06
NP_000236	STKc_RSK_N	cd05582	1081	1387	9.2e-05
NP_000236	STKc_p70S6K	cd05584	1081	1385	5.9e-05
NP_000236	PKc_MKK4	cd06616	1081	1362	4.8e-06
NP_000236	STKc_MEKK4	cd06626	1081	1334	8.7e-06
NP_000236	STKc_MAPKKK_Byr2_lik	cd06628	1081	1339	6.8e-12
NP_000236	STKc_FA2-like	cd08529	1081	1340	4.6e-08
NP_000236	PTKc	cd00192	1082	1338	2.1e-142
NP_000236	PTK_Jak_rpt1	cd05037	1082	1338	2.8e-08
NP_000236	PTKc_Ack_like	cd05040	1082	1339	5.7e-53
NP_000236	PTKc_Fes_like	cd05041	1082	1339	3.8e-62
NP_000236	PTKc_Aatyk	cd05042	1082	1336	2.3e-17
NP_000236	PTKc_c-ros	cd05044	1082	1339	3.4e-77
NP_000236	PTKc_Tie	cd05047	1082	1342	3.4e-50
NP_000236	PTKc_Met_Ron	cd05058	1082	1343	5.7e-196
NP_000236	PTKc_Syk_like	cd05060	1082	1342	8.4e-65
NP_000236	PTK_Jak2_Jak3_rpt1	cd05078	1082	1338	4.9e-09
NP_000236	PTK_Jak1_rpt1	cd05077	1082	1338	3.4e-08
NP_000236	PTKc_Fes	cd05084	1082	1339	1.3e-61
NP_000236	PTKc_Fer	cd05085	1082	1339	9.8e-59
NP_000236	PTKc_Aatyk2	cd05086	1082	1340	2.6e-24
NP_000236	PTKc_Aatyk1_Aatyk3	cd05087	1082	1339	5.2e-24
NP_000236	PTKc_Syk	cd05116	1082	1342	5.1e-51
NP_000236	STKc_CMGC	cd05118	1082	1341	3.2e-08
NP_000236	STKc_PKC	cd05570	1082	1350	3.2e-07
NP_000236	STKc_PKB	cd05571	1082	1390	5.2e-06
NP_000236	STKc_nPKC_epsilon	cd05591	1082	1388	9.7e-05
NP_000236	STKc_nPKC_theta_delt	cd05592	1082	1389	2e-05
NP_000236	STKc_PKB_gamma	cd05593	1082	1388	5.2e-05
NP_000236	STKc_PKB_alpha	cd05594	1082	1390	0.00018
NP_000236	STKc_PKB_beta	cd05595	1082	1390	0.00056
NP_000236	STKc_SGK2	cd05603	1082	1388	0.0003
NP_000236	STKc_SGK	cd05575	1082	1389	0.00028
NP_000236	STKc_nPKC_theta	cd05619	1082	1364	3.2e-05
NP_000236	STKc_aPKC_zeta	cd05617	1082	1390	0.0007
NP_000236	PKc_MAPKK	cd06605	1082	1342	4.1e-05
NP_000236	STKc_MEKK3_like	cd06625	1082	1339	3.4e-09
NP_000236	STKc_MEKK1	cd06630	1082	1342	2.9e-06
NP_000236	STKc_MEKK1_plant	cd06632	1082	1334	3e-10
NP_000236	STKc_YSK4	cd06631	1082	1339	2.2e-08
NP_000236	STKc_NAK1_like	cd06917	1082	1353	1.3e-08
NP_000236	STKc_CDK_like	cd07829	1082	1342	9.4e-09
NP_000236	STKc_MAK_like	cd07830	1082	1341	1.8e-05
NP_000236	STKc_CDK5	cd07839	1082	1350	7.3e-06
NP_000236	STKc_CDC2L1	cd07843	1082	1341	2.9e-05
NP_000236	STKc_CdkB_plant	cd07837	1082	1367	3.3e-06
NP_000236	STKc_Nek	cd08215	1082	1339	1.1e-12
NP_000236	STKc_Nek2	cd08217	1082	1337	1.6e-07
NP_000236	STKc_Nek8	cd08220	1082	1339	3.4e-05
NP_000236	STKc_beta_ARK	cd05606	1083	1371	6.5e-05
NP_000236	STKc_GRK3	cd05633	1083	1365	0.00033
NP_000236	PKc	cd00180	1084	1337	1.3e-57
NP_000236	PTKc_Zap-70	cd05115	1084	1342	3.9e-52
NP_000236	STKc_AGC	cd05123	1084	1341	6e-09
NP_000236	STKc_cGK_PKG	cd05572	1084	1348	1.2e-06
NP_000236	STKc_YPK1_like	cd05585	1084	1387	0.00013
NP_000236	STKc_MAST_like	cd05579	1084	1320	2e-06
NP_000236	STKc_GRK	cd05577	1084	1347	3.6e-06
NP_000236	STKc_GRK7	cd05607	1084	1364	6.8e-05
NP_000236	STKc_GRK1	cd05608	1084	1364	7.3e-06
NP_000236	PKc_MAPKK_Byr1_like	cd06620	1110	1354	0.00015
NP_000236	PKc_MKK3_6	cd06617	1110	1339	5.9e-06
NP_000236	Sema	pfam01403	55	500	1.7e-170
NP_000236	PSI	pfam01437	519	562	7e-12
NP_000236	TIG	pfam01833	563	654	7.3e-16
NP_000236	TIG	pfam01833	657	738	1.8e-14
NP_000236	TIG	pfam01833	742	835	2.9e-09
NP_000236	Pkinase	pfam00069	1078	1337	7.6e-39
NP_000236	Sema	smart00630	52	487	2.1e-145
NP_000236	PSI	smart00423	520	562	5.1e-09
NP_000236	IPT	smart00429	562	655	2e-19
NP_000236	IPT	smart00429	656	739	1.8e-19
NP_000236	IPT	smart00429	741	836	1.2e-22
NP_000236	IPT	smart00429	838	934	1.1e-08
NP_000236	Pkinase_Tyr	pfam07714	1078	1337	3.5e-143
NP_000236	TyrKc	smart00219	1078	1337	1.9e-133
NP_000236	STYKc	smart00221	1078	1339	2.6e-49
NP_000236	S_TKc	smart00220	1088	1341	4.8e-42

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258