Results for the gene: AURKA

Results for Proteins associated with the Gene: AURKA

AURKA

6790

O14965 NP_940839 NP_940837 NP_940836 NP_940838 NP_940835 NP_003591

NCBI

Known Diseases associated with this Protein:

COLON CANCER, SUSCEPTIBILITY TO

			5 18 5 10 8

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

Clicking a check box on the left will display or hide the corresponding domain(s).

To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: O14965

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RefSeq Protein: NP_940839

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RefSeq Protein: NP_940837

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RefSeq Protein: NP_940836

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RefSeq Protein: NP_940838

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RefSeq Protein: NP_940835

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RefSeq Protein: NP_003591

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Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_003591	STKc_ROCK2	cd05621	94	402	7.3e-10
NP_003591	STKc_ROCK1	cd05622	94	401	5.7e-09
NP_003591	STKc_TAO3	cd06633	99	402	1.5e-06
NP_003591	STKc_PAK1	cd06654	106	402	9.7e-10
NP_003591	STKc_PAK3	cd06656	107	401	4.6e-10
NP_003591	STKc_PAK5	cd06658	107	401	1.1e-08
NP_003591	PTKc_DDR2	cd05095	108	401	8.9e-05
NP_003591	STKc_JNK2	cd07876	108	402	1.7e-05
NP_003591	STKc_PAK4	cd06657	109	398	1.1e-08
NP_003591	STKc_PAK	cd06614	110	398	4.3e-21
NP_003591	PTKc_FGFR2	cd05101	111	388	1.1e-06
NP_003591	STKc_TAO	cd06607	111	402	1.4e-08
NP_003591	STKc_PAK_I	cd06647	111	400	8.6e-16
NP_003591	STKc_TAO2	cd06634	111	403	8.3e-09
NP_003591	STKc_PAK_II	cd06648	111	397	1.4e-13
NP_003591	STKc_PAK2	cd06655	111	403	8.4e-10
NP_003591	STKc_PAK6	cd06659	111	402	3e-13
NP_003591	PTKc_FGFR3	cd05100	114	403	4.7e-05
NP_003591	STKc_myosinIIIA	cd06638	114	383	8.1e-10
NP_003591	STKc_myosinIIIB	cd06639	114	384	2.3e-10
NP_003591	PTKc_FGFR1	cd05098	115	391	2.9e-06
NP_003591	STKc_MAP4K4_6	cd06636	115	383	4.8e-07
NP_003591	STKc_JNK3	cd07874	115	400	0.0004
NP_003591	STKc_JNK	cd07850	116	403	2.6e-06
NP_003591	STKc_p38alpha_MAPK14	cd07877	116	403	1.5e-05
NP_003591	STKc_CDK9	cd07865	118	383	1.1e-11
NP_003591	STKc_p38delta_MAPK13	cd07879	119	403	0.00015
NP_003591	STKc_p38beta_MAPK11	cd07878	120	403	1.9e-06
NP_003591	STKc_p38gamma_MAPK12	cd07880	120	403	5.1e-07
NP_003591	STKc_TAO1	cd06635	122	402	3.1e-08
NP_003591	PKc_MKK7	cd06618	122	403	8.3e-13
NP_003591	STKc_STK10_LOK	cd06644	122	402	3.3e-15
NP_003591	STKc_p38	cd07851	122	401	2.1e-10
NP_003591	STKc_JNK1	cd07875	122	402	0.00042
NP_003591	PTKc_Jak_rpt2	cd05038	123	385	1.6e-09
NP_003591	PTKc_FGFR4	cd05099	123	400	3.1e-07
NP_003591	STKc_MAP4K3	cd06645	123	382	6.6e-10
NP_003591	STKc_MAP4K5	cd06646	123	382	9e-09
NP_003591	STKc_ASK	cd06624	124	383	5.2e-21
NP_003591	PTKc_EGFR_like	cd05057	125	397	3.6e-06
NP_003591	PTKc_TrkA	cd05092	125	389	6.4e-08
NP_003591	PTKc_VEGFR2	cd05103	125	386	0.001
NP_003591	PTKc_HER2	cd05109	125	394	1e-05
NP_003591	PTK_HER3	cd05111	125	397	2.1e-05
NP_003591	STKc_CDK10	cd07845	125	397	1.5e-13
NP_003591	PTKc_ALK_LTK	cd05036	126	385	1.9e-12
NP_003591	PTKc_FGFR	cd05053	126	385	7.2e-08
NP_003591	PTKc_FAK	cd05056	126	389	8.7e-11
NP_003591	PTKc_EGFR	cd05108	126	403	0.00029
NP_003591	PTKc_Ror	cd05048	127	382	5.2e-07
NP_003591	PTKc_Trk	cd05049	127	380	1.8e-10
NP_003591	PTKc_Musk	cd05050	127	380	1.1e-07
NP_003591	PTKc_DDR	cd05051	127	380	0.00043
NP_003591	PTKc_EphR_A10	cd05064	127	387	0.00051
NP_003591	PTKc_Tie2	cd05088	127	393	6.1e-07
NP_003591	PTKc_Ror1	cd05090	127	382	2.9e-05
NP_003591	PTKc_Ror2	cd05091	127	382	1.2e-05
NP_003591	PTKc_TrkB	cd05093	127	396	1.5e-06
NP_003591	PTKc_TrkC	cd05094	127	402	0.00019
NP_003591	STKc_MEKK4	cd06626	127	383	2.5e-17
NP_003591	PKc_MEK2	cd06649	127	394	1.7e-06
NP_003591	PKc_MEK1	cd06650	127	398	9e-06
NP_003591	STKc_CDK8_like	cd07842	127	383	3e-10
NP_003591	STKc_TEY_MAPK_plant	cd07858	127	402	1.9e-06
NP_003591	STKc_CDK12	cd07864	127	383	9.3e-16
NP_003591	PTKc_InsR_like	cd05032	128	380	2.5e-07
NP_003591	PTKc_EphR	cd05033	128	383	1e-05
NP_003591	PTKc_Csk_like	cd05039	128	381	2.7e-07
NP_003591	PTKc_Abl	cd05052	128	382	4.3e-10
NP_003591	PTKc_InsR	cd05061	128	388	1.7e-05
NP_003591	PTKc_IGF-1R	cd05062	128	385	0.00012
NP_003591	PTKc_EphR_A	cd05066	128	383	3e-05
NP_003591	PTKc_Lck_Blk	cd05067	128	381	1.3e-05
NP_003591	PTKc_Frk_like	cd05068	128	381	2.5e-09
NP_003591	PTKc_Yes	cd05069	128	381	8.2e-06
NP_003591	PTKc_Fyn_Yrk	cd05070	128	381	7.2e-05
NP_003591	PTKc_Src	cd05071	128	383	0.00022
NP_003591	PTKc_Lyn	cd05072	128	381	4.8e-08
NP_003591	PTKc_Hck	cd05073	128	381	5.8e-07
NP_003591	PTKc_Csk	cd05082	128	381	2.3e-07
NP_003591	PTKc_Chk	cd05083	128	381	6.9e-06
NP_003591	PTKc_Btk_Bmx	cd05113	128	382	1.8e-11
NP_003591	PTKc_Srm_Brk	cd05148	128	381	4.7e-10
NP_003591	PKc_MKK4	cd06616	128	399	1.5e-08
NP_003591	STKc_SLK	cd06643	128	400	3.8e-11
NP_003591	STKc_ERK5	cd07855	128	402	1.3e-09
NP_003591	PTKc_EphR_A2	cd05063	129	383	4.4e-05
NP_003591	PTKc_EphR_B	cd05065	129	385	5.3e-05
NP_003591	PTKc_HER4	cd05110	129	398	0.00084
NP_003591	PTKc_Itk	cd05112	129	382	6.9e-10
NP_003591	STKc_MAP4K3_like	cd06613	129	382	2.1e-18
NP_003591	STKc_PCTAIRE_like	cd07844	129	383	2.7e-18
NP_003591	STKc_BUR1	cd07866	129	383	1.6e-12
NP_003591	STKc_PFTAIRE1	cd07869	129	395	3.4e-06
NP_003591	STKc_PFTAIRE2	cd07870	129	383	4.9e-09
NP_003591	STKc_PCTAIRE2	cd07872	129	403	1.1e-08
NP_003591	STKc_PCTAIRE1	cd07873	129	395	1.9e-08
NP_003591	STKc_PCTAIRE3	cd07871	129	383	4.8e-10
NP_003591	PTKc_Tie1	cd05089	130	399	4.2e-07
NP_003591	PTKc_Tec_Rlk	cd05114	130	382	4e-12
NP_003591	STKc_TNIK	cd06637	130	383	2.7e-09
NP_003591	STKc_MAPK15	cd07852	130	403	1.4e-10
NP_003591	STKc_CDC2L6	cd07867	130	383	1.2e-05
NP_003591	STKc_CDK8	cd07868	130	383	3.6e-05
NP_003591	STKc_Nek6	cd08228	130	386	5.4e-17
NP_003591	STKc_Nek7	cd08229	130	386	1.9e-16
NP_003591	STKc_Nek6_Nek7	cd08224	130	386	3e-22
NP_003591	PTKc_Src_like	cd05034	131	381	1.9e-09
NP_003591	STKc_ROCK_NDR_like	cd05573	131	403	2.7e-20
NP_003591	STKc_phototropin_lik	cd05574	131	391	3.3e-20
NP_003591	STKc_PKA	cd05580	131	390	7.8e-42
NP_003591	STKc_PDK1	cd05581	131	383	9.5e-64
NP_003591	STKc_DMPK_like	cd05597	131	403	2.1e-09
NP_003591	STKc_LATS	cd05598	131	403	4.1e-10
NP_003591	STKc_NDR_like	cd05599	131	401	6.8e-13
NP_003591	STKc_Sid2p_Dbf2p	cd05600	131	403	2.4e-13
NP_003591	STKc_CRIK	cd05601	131	403	7.8e-15
NP_003591	STKc_MAST	cd05609	131	403	7e-19
NP_003591	STKc_PRKX_like	cd05612	131	400	3.4e-43
NP_003591	STKc_MRCK_alpha	cd05623	131	403	4.8e-10
NP_003591	STKc_MRCK_beta	cd05624	131	403	6.8e-10
NP_003591	STKc_LATS2	cd05626	131	403	2.9e-05
NP_003591	STKc_NDR2	cd05627	131	403	5.4e-08
NP_003591	STKc_NDR1	cd05628	131	403	4.6e-11
NP_003591	STKc_NDR_like_fungal	cd05629	131	403	2.7e-07
NP_003591	PKc_MAPKK	cd06605	131	388	9.7e-15
NP_003591	STKc_myosinIII_like	cd06608	131	383	1.3e-15
NP_003591	STKc_OSR1_SPAK	cd06610	131	383	5.9e-17
NP_003591	STKc_SLK_like	cd06611	131	397	2e-13
NP_003591	STKc_MST1_2	cd06612	131	383	1.8e-16
NP_003591	PKc_MEK	cd06615	131	396	1.4e-12
NP_003591	PKc_MKK3_6	cd06617	131	398	5.9e-14
NP_003591	PKc_MKK5	cd06619	131	400	8.7e-07
NP_003591	PKc_MAPKK_Byr1_like	cd06620	131	399	2.5e-11
NP_003591	PKc_MAPKK_Pek1_like	cd06621	131	393	3.6e-15
NP_003591	PKc_MAPKK_PBS2_like	cd06622	131	402	1e-10
NP_003591	PKc_MAPKK_plant_like	cd06623	131	389	1.4e-33
NP_003591	STKc_MST3_like	cd06609	131	403	2.5e-21
NP_003591	STKc_MEKK3_like	cd06625	131	383	3.8e-25
NP_003591	STKc_MST4	cd06640	131	401	1.8e-19
NP_003591	STKc_MST3	cd06641	131	401	5.6e-17
NP_003591	STKc_STK25-YSK1	cd06642	131	401	4.5e-19
NP_003591	STKc_MEKK2	cd06652	131	384	1.1e-09
NP_003591	STKc_MEKK3_like_1	cd06653	131	383	4.5e-18
NP_003591	STKc_CDKL	cd07833	131	383	5.7e-14
NP_003591	STKc_CdkB_plant	cd07837	131	384	1.8e-12
NP_003591	STKc_CDC2L1	cd07843	131	383	4.3e-13
NP_003591	STKc_CDKL2_3	cd07846	131	383	2e-11
NP_003591	STKc_CDKL1_4	cd07847	131	383	4.3e-18
NP_003591	STKc_ERK1_2_like	cd07849	131	400	5.9e-09
NP_003591	STKc_CDKL5	cd07848	131	383	6e-07
NP_003591	STKc_CDK6	cd07862	131	383	1.2e-06
NP_003591	SPS1	COG0515	131	403	1e-47
NP_003591	PTKc_RET	cd05045	132	387	8.5e-05
NP_003591	PTKc_Tec_like	cd05059	132	384	4.6e-10
NP_003591	PKc_STE	cd05122	132	382	6.7e-60
NP_003591	STKc_Yank1	cd05578	132	383	6.4e-42
NP_003591	STKc_MSK_N	cd05583	132	402	3.8e-35
NP_003591	STKc_cPKC	cd05587	132	403	6.7e-21
NP_003591	STKc_GRK4_like	cd05605	132	396	1.7e-15
NP_003591	STKc_MSK1_N	cd05613	132	402	4.1e-27
NP_003591	STKc_MSK2_N	cd05614	132	401	2.2e-17
NP_003591	STKc_cPKC_alpha	cd05615	132	403	7.4e-11
NP_003591	STKc_cPKC_beta	cd05616	132	403	8.9e-10
NP_003591	STKc_GRK6	cd05630	132	403	2.5e-08
NP_003591	STKc_GRK4	cd05631	132	396	7e-10
NP_003591	STKc_GRK5	cd05632	132	396	1.1e-08
NP_003591	STKc_MAPKKK	cd06606	132	383	1.5e-50
NP_003591	STKc_Cdc7_like	cd06627	132	383	1.4e-26
NP_003591	STKc_MAPKKK_Byr2_lik	cd06628	132	383	2.8e-35
NP_003591	STKc_MEKK1	cd06630	132	384	2.4e-15
NP_003591	STKc_YSK4	cd06631	132	383	5.5e-12
NP_003591	STKc_MEKK3	cd06651	132	385	2.2e-16
NP_003591	STKc_CCRK	cd07832	132	384	3.8e-18
NP_003591	STKc_MAPK	cd07834	132	402	2.2e-11
NP_003591	STKc_Pho85	cd07836	132	383	1e-20
NP_003591	STKc_CDK5	cd07839	132	383	8.7e-12
NP_003591	STKc_CDK7	cd07841	132	394	5.5e-17
NP_003591	STKc_NLK	cd07853	132	403	2.4e-06
NP_003591	STKc_MPK1	cd07857	132	399	4.3e-10
NP_003591	STKc_TDY_MAPK_plant	cd07859	132	403	4.8e-06
NP_003591	STKc_CDK2_3	cd07860	132	383	1e-22
NP_003591	STKc_CDK1_euk	cd07861	132	383	3.9e-24
NP_003591	STKc_CDK4	cd07863	132	383	3.4e-08
NP_003591	STKc_Nek	cd08215	132	383	1.4e-40
NP_003591	STKc_Nek2	cd08217	132	383	6.7e-20
NP_003591	STKc_Nek1	cd08218	132	383	6.2e-31
NP_003591	STKc_Nek3	cd08219	132	383	1.4e-26
NP_003591	STKc_Nek8	cd08220	132	383	3.8e-27
NP_003591	STKc_Nek9	cd08221	132	383	7.7e-14
NP_003591	STKc_Nek11	cd08222	132	383	3e-22
NP_003591	STKc_Nek4	cd08223	132	383	4.8e-19
NP_003591	STKc_Nek5	cd08225	132	383	2.6e-30
NP_003591	STKc_Nek10	cd08528	132	383	6.6e-14
NP_003591	STKc_FA2-like	cd08529	132	383	1.3e-15
NP_003591	STKc_CNK2-like	cd08530	132	383	9.3e-15
NP_003591	PTKc_Axl_like	cd05035	133	382	1.1e-06
NP_003591	PTK_Ryk	cd05043	133	359	0.00017
NP_003591	PTKc_Tyro3	cd05074	133	382	5.1e-06
NP_003591	PTKc_Axl	cd05075	133	382	3.2e-05
NP_003591	PTKc_Jak1_rpt2	cd05079	133	385	6.4e-05
NP_003591	PTKc_Tyk2_rpt2	cd05080	133	386	1.1e-05
NP_003591	PTKc_Jak2_Jak3_rpt2	cd05081	133	403	8.9e-08
NP_003591	STKc_CMGC	cd05118	133	383	2.9e-19
NP_003591	STKc_PKN	cd05589	133	403	6.7e-22
NP_003591	STKc_LATS1	cd05625	133	403	1.4e-05
NP_003591	STKc_MAPKKK_Bck1_lik	cd06629	133	383	1e-15
NP_003591	STKc_CDK_like	cd07829	133	383	1.7e-22
NP_003591	STKc_MAK_like	cd07830	133	383	1.8e-14
NP_003591	STKc_CDK1_like	cd07835	133	383	1.3e-20
NP_003591	STKc_CDK9_like	cd07840	133	383	2.3e-18
NP_003591	STKc_MAPK4_6	cd07854	133	403	1.8e-06
NP_003591	STKc_Sty1_Hog1	cd07856	133	401	8.4e-09
NP_003591	STKc_CDK4_6_like	cd07838	133	383	2.9e-14
NP_003591	PK_STRAD	cd08216	134	390	4.8e-06
NP_003591	STKc_p70S6K	cd05584	136	402	5.2e-26
NP_003591	STKc_MEKK1_plant	cd06632	136	383	8.2e-18
NP_003591	PTKc	cd00192	137	382	7.6e-14
NP_003591	PTK_Jak_rpt1	cd05037	137	378	1.3e-05
NP_003591	PTKc_Ack_like	cd05040	137	380	5.9e-13
NP_003591	PTKc_Fes_like	cd05041	137	383	8e-12
NP_003591	PTKc_Aatyk	cd05042	137	380	3.1e-06
NP_003591	PTKc_c-ros	cd05044	137	380	2.1e-07
NP_003591	PTKc_Met_Ron	cd05058	137	387	2.3e-05
NP_003591	PTKc_Syk_like	cd05060	137	379	5.5e-08
NP_003591	PTK_Jak2_Jak3_rpt1	cd05078	137	379	5.4e-05
NP_003591	PTKc_Fes	cd05084	137	383	9.5e-09
NP_003591	PTKc_Syk	cd05116	137	383	6.4e-08
NP_003591	PTKc_Aatyk1_Aatyk3	cd05087	137	385	0.00015
NP_003591	STKc_PKC	cd05570	137	403	3.8e-19
NP_003591	STKc_PKB	cd05571	137	402	1.4e-20
NP_003591	STKc_SGK	cd05575	137	403	1.1e-14
NP_003591	STKc_RSK_N	cd05582	137	403	3.5e-28
NP_003591	STKc_aPKC	cd05588	137	403	9.9e-09
NP_003591	STKc_nPKC_epsilon	cd05591	137	401	1.4e-18
NP_003591	STKc_nPKC_theta_delt	cd05592	137	403	2.4e-20
NP_003591	STKc_PKB_gamma	cd05593	137	403	8.8e-12
NP_003591	STKc_PKB_alpha	cd05594	137	401	3.1e-13
NP_003591	STKc_PKB_beta	cd05595	137	400	5.6e-16
NP_003591	STKc_SGK1	cd05602	137	403	2.2e-11
NP_003591	STKc_SGK2	cd05603	137	401	1e-16
NP_003591	STKc_nPKC_eta	cd05590	137	403	1.8e-22
NP_003591	STKc_SGK3	cd05604	137	403	2.6e-12
NP_003591	STKc_aPKC_zeta	cd05617	137	400	1.7e-08
NP_003591	STKc_aPKC_iota	cd05618	137	403	6.8e-07
NP_003591	STKc_nPKC_theta	cd05619	137	403	1.4e-16
NP_003591	STKc_nPKC_delta	cd05620	137	403	1.8e-07
NP_003591	STKc_MOK	cd07831	137	383	2.8e-13
NP_003591	STKc_Rim15_like	cd05611	138	382	4.2e-14
NP_003591	PKc	cd00180	139	381	8.2e-85
NP_003591	PTK_CCK4	cd05046	139	380	1.6e-07
NP_003591	PTKc_Tie	cd05047	139	379	1.1e-06
NP_003591	PTKc_Fer	cd05085	139	383	8.1e-09
NP_003591	PTKc_Zap-70	cd05115	139	386	3.9e-07
NP_003591	STKc_AGC	cd05123	139	383	1.1e-70
NP_003591	STKc_cGK_PKG	cd05572	139	389	9.8e-44
NP_003591	STKc_GRK	cd05577	139	391	7.1e-13
NP_003591	STKc_MAST_like	cd05579	139	388	2.1e-34
NP_003591	STKc_Sck1_like	cd05586	139	403	2.9e-10
NP_003591	STKc_beta_ARK	cd05606	139	403	1.1e-09
NP_003591	STKc_GRK7	cd05607	139	395	3.9e-09
NP_003591	STKc_GRK1	cd05608	139	403	1.8e-11
NP_003591	STKc_YPK1_like	cd05585	139	403	1.8e-26
NP_003591	STKc_GRK3	cd05633	139	403	5.1e-08
NP_003591	STKc_NAK1_like	cd06917	139	402	1.4e-16
NP_003591	Pkinase	pfam00069	133	383	8.5e-84
NP_003591	Pkinase_Tyr	pfam07714	133	381	1.6e-18
NP_003591	TyrKc	smart00219	133	383	2.2e-15
NP_003591	STYKc	smart00221	133	383	7.8e-93
NP_003591	S_TKc	smart00220	143	383	7.2e-101
NP_003591	KIND	smart00750	216	391	9.2e-07

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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