Results for the protein: NP

Results for the Protein: NP_001177728

299829210

10733

PLK4

NCBI

serine/threonine-protein kinase PLK4 isoform 2 [Homo sapiens]

			0 3 0 3 0

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RefSeq Protein: NP_001177728

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK	cd05596	3e-06	1	297
STKc_ROCK2	cd05621	1.7e-05	1	295
PKc_MKK7	cd06618	1.4e-09	1	253
STKc_TAO3	cd06633	0.00054	1	276
STKc_myosinIIIB	cd06639	1.9e-06	1	234
STKc_PAK_I	cd06647	4.1e-07	1	259
STKc_PAK_II	cd06648	7.5e-11	1	245
STKc_PAK1	cd06654	9.7e-07	1	261
STKc_PAK2	cd06655	1.3e-06	1	255
STKc_PAK4	cd06657	6.8e-05	1	252
STKc_PAK5	cd06658	3.5e-05	1	251
STKc_PAK6	cd06659	8.5e-09	1	261
STKc_PAK3	cd06656	9.2e-08	1	267
STKc_p38	cd07851	1.7e-09	1	267
STKc_Sty1_Hog1	cd07856	2.3e-08	1	265
STKc_p38alpha_MAPK14	cd07877	0.0003	1	295
STKc_p38beta_MAPK11	cd07878	0.00027	1	272
STKc_p38gamma_MAPK12	cd07880	3.7e-05	1	272
STKc_CDK9	cd07865	2e-09	1	233
STKc_PAK	cd06614	1.1e-16	2	247
STKc_TAO1	cd06635	7.8e-06	2	276
STKc_myosinIIIA	cd06638	1.7e-07	2	233
STKc_MAP4K3	cd06645	6.1e-08	2	232
STKc_MAP4K5	cd06646	8.7e-07	2	232
STKc_STK10_LOK	cd06644	3.6e-08	2	253
STKc_CDK10	cd07845	2.9e-12	2	244
PTKc_EphR_A2	cd05063	0.00036	3	232
STKc_ASK	cd06624	2.9e-10	3	233
STKc_MAP4K4_6	cd06636	1.1e-05	3	233
STKc_JNK	cd07850	0.00019	3	262
STKc_CDK6	cd07862	5.1e-05	3	233
PTKc_EGFR_like	cd05057	1.6e-05	4	225
PTK_Ryk	cd05043	0.00019	5	213
PTKc_PDGFR	cd05055	9.5e-05	5	214
PTKc_FAK	cd05056	9.9e-07	5	232
STKc_ROCK1	cd05622	9.8e-06	5	296
STKc_TNIK	cd06637	1.1e-07	5	233
STKc_MAPK15	cd07852	1.9e-10	5	258
STKc_MAPK4_6	cd07854	4.5e-08	5	270
STKc_PFTAIRE2	cd07870	4.1e-07	5	233
PTKc_Ror	cd05048	5.7e-05	6	188
STKc_CDK12	cd07864	5.5e-10	6	233
PTKc_ALK_LTK	cd05036	4.3e-07	7	233
PTKc_Jak_rpt2	cd05038	2.3e-07	7	235
PKc_MAPKK_Pek1_like	cd06621	5.2e-07	7	245
STKc_MST4	cd06640	2.9e-08	7	255
STKc_STK25-YSK1	cd06642	9.4e-09	7	254
STKc_SLK	cd06643	1.4e-08	7	250
STKc_MST3	cd06641	1.8e-07	7	255
STKc_CDK5	cd07839	2.2e-09	7	233
STKc_TEY_MAPK_plant	cd07858	1.3e-06	7	278
PTKc_InsR_like	cd05032	1.4e-06	8	230
PTKc_EphR	cd05033	6.9e-06	8	232
PTKc_Trk	cd05049	4.4e-06	8	230
PTKc_Abl	cd05052	4e-05	8	232
PTKc_FGFR	cd05053	1.3e-05	8	214
PTKc_EphR_B	cd05065	0.00061	8	232
PTKc_Frk_like	cd05068	9.9e-08	8	231
PTKc_Fyn_Yrk	cd05070	0.00027	8	231
PTKc_Lyn	cd05072	2e-05	8	231
PTKc_Csk	cd05082	0.00025	8	231
PTKc_Chk	cd05083	0.00011	8	236
PTKc_Tie2	cd05088	2.7e-05	8	250
PTKc_TrkA	cd05092	0.00022	8	238
PTKc_TrkB	cd05093	0.00034	8	245
PTKc_HER2	cd05109	0.00057	8	244
PTK_HER3	cd05111	0.00046	8	225
PTKc_Itk	cd05112	1e-06	8	232
PTKc_EGFR	cd05108	0.00014	8	283
PTKc_Btk_Bmx	cd05113	3.7e-06	8	228
PKc_MKK4	cd06616	1.8e-06	8	252
PKc_MAPKK_Byr1_like	cd06620	1.4e-06	8	248
PKc_MEK1	cd06650	0.001	8	266
PKc_MEK2	cd06649	0.00094	8	260
STKc_BUR1	cd07866	1.4e-12	8	233
STKc_PFTAIRE1	cd07869	0.00011	8	246
STKc_PCTAIRE3	cd07871	6.8e-08	8	233
STKc_PCTAIRE2	cd07872	1.4e-06	8	261
STKc_PCTAIRE1	cd07873	6.8e-06	8	249
STKc_PCTAIRE_like	cd07844	2e-08	8	263
STKc_Nek8	cd08220	2.8e-09	8	233
PTKc_Csk_like	cd05039	4.4e-07	9	231
PTKc_Tie1	cd05089	2.2e-05	9	256
PTKc_Tec_Rlk	cd05114	0.0001	9	232
STKc_CDC2L1	cd07843	1e-12	9	233
STKc_Nek6_Nek7	cd08224	2.9e-11	9	236
STKc_Nek7	cd08229	2.1e-09	9	236
STKc_Nek6	cd08228	2.1e-07	9	236
PTKc_Src_like	cd05034	1.1e-09	10	231
PTKc_Musk	cd05050	1.2e-05	10	235
PTKc_Yes	cd05069	5.9e-05	10	231
PTKc_Src	cd05071	0.00011	10	233
PTKc_Hck	cd05073	0.00012	10	231
PTKc_Srm_Brk	cd05148	3.2e-09	10	231
STKc_ROCK_NDR_like	cd05573	5.6e-15	10	305
STKc_phototropin_lik	cd05574	6.4e-13	10	252
STKc_PDK1	cd05581	7.2e-43	10	233
STKc_DMPK_like	cd05597	4.7e-08	10	294
STKc_LATS	cd05598	1.5e-07	10	281
STKc_CRIK	cd05601	7.3e-12	10	287
STKc_NDR_like	cd05599	9.9e-10	10	318
STKc_Sid2p_Dbf2p	cd05600	8.3e-09	10	277
STKc_MAST	cd05609	1.7e-10	10	306
STKc_PRKX_like	cd05612	1.9e-16	10	260
STKc_PKA	cd05580	8.2e-19	10	269
STKc_MRCK_alpha	cd05623	2.9e-07	10	314
STKc_MRCK_beta	cd05624	4.1e-07	10	283
STKc_NDR1	cd05628	7.3e-07	10	318
STKc_NDR_like_fungal	cd05629	2.8e-06	10	321
STKc_NDR2	cd05627	2.4e-05	10	316
STKc_LATS2	cd05626	3.9e-05	10	281
PKc_MAPKK	cd06605	4.8e-10	10	238
STKc_MST3_like	cd06609	1e-16	10	252
STKc_myosinIII_like	cd06608	1e-11	10	233
STKc_OSR1_SPAK	cd06610	3.6e-12	10	233
STKc_MST1_2	cd06612	9.1e-16	10	233
STKc_MAP4K3_like	cd06613	7.5e-14	10	232
PKc_MEK	cd06615	6.5e-09	10	251
PKc_MKK3_6	cd06617	4.3e-09	10	252
PKc_MKK5	cd06619	0.00014	10	255
PKc_MAPKK_PBS2_like	cd06622	1.1e-07	10	289
PKc_MAPKK_plant_like	cd06623	1e-16	10	239
STKc_MEKK3_like	cd06625	1.2e-15	10	233
STKc_MEKK2	cd06652	5.4e-07	10	234
STKc_MEKK3_like_1	cd06653	7.5e-08	10	233
STKc_NAK1_like	cd06917	3e-11	10	249
STKc_CDKL	cd07833	3.8e-10	10	233
STKc_CdkB_plant	cd07837	8e-13	10	234
STKc_CDKL2_3	cd07846	1.7e-09	10	233
STKc_CDKL1_4	cd07847	1.2e-06	10	233
STKc_CDKL5	cd07848	0.00076	10	233
STKc_ERK1_2_like	cd07849	1.7e-08	10	264
SPS1	COG0515	8e-45	10	393
PTKc_Tec_like	cd05059	9e-08	11	229
PKc_STE	cd05122	3.6e-18	11	232
STKc_Yank1	cd05578	1.2e-17	11	233
STKc_MSK_N	cd05583	2.4e-11	11	250
STKc_GRK4_like	cd05605	4.9e-09	11	255
STKc_MSK1_N	cd05613	1.3e-08	11	253
STKc_MSK2_N	cd05614	1.9e-10	11	283
STKc_cPKC_alpha	cd05615	1.6e-10	11	282
STKc_cPKC_beta	cd05616	5.5e-09	11	313
STKc_cPKC	cd05587	4.5e-18	11	309
STKc_GRK6	cd05630	1.4e-05	11	255
STKc_GRK5	cd05632	1.6e-07	11	255
STKc_GRK4	cd05631	2.3e-06	11	255
STKc_TAO	cd06607	5.6e-07	11	276
STKc_Cdc7_like	cd06627	4e-21	11	233
STKc_MAPKKK_Byr2_lik	cd06628	1.4e-10	11	233
STKc_MAPKKK	cd06606	4e-30	11	233
STKc_YSK4	cd06631	5.2e-11	11	233
STKc_MEKK1	cd06630	1.5e-10	11	234
STKc_TAO2	cd06634	9.5e-06	11	277
STKc_MEKK3	cd06651	2.5e-10	11	235
STKc_CCRK	cd07832	2.3e-13	11	234
STKc_MAPK	cd07834	8.3e-12	11	261
STKc_CDK7	cd07841	6.5e-13	11	245
STKc_CDK8_like	cd07842	4.4e-08	11	233
STKc_Pho85	cd07836	4.6e-07	11	233
STKc_NLK	cd07853	5e-09	11	305
STKc_CDK2_3	cd07860	1.8e-06	11	233
STKc_CDK1_euk	cd07861	3.4e-06	11	233
STKc_CDK4	cd07863	8.3e-06	11	233
STKc_MPK1	cd07857	1.8e-09	11	262
STKc_TDY_MAPK_plant	cd07859	4.7e-06	11	320
STKc_Nek	cd08215	4e-31	11	233
STKc_Nek2	cd08217	2.3e-13	11	233
STKc_Nek1	cd08218	1.6e-21	11	233
STKc_Nek3	cd08219	1.2e-21	11	233
STKc_Nek11	cd08222	1.1e-11	11	233
STKc_Nek5	cd08225	2e-22	11	233
STKc_Nek4	cd08223	1.8e-12	11	233
STKc_Nek10	cd08528	1.7e-07	11	230
STKc_FA2-like	cd08529	2.7e-13	11	227
STKc_CNK2-like	cd08530	1e-14	11	233
PTKc_Axl_like	cd05035	0.00085	12	232
PTKc_Tyk2_rpt2	cd05080	0.00021	12	236
PTKc_Jak2_Jak3_rpt2	cd05081	3.9e-06	12	235
STKc_CMGC	cd05118	1.7e-15	12	233
STKc_PKN	cd05589	1.3e-11	12	305
STKc_LATS1	cd05625	1.4e-05	12	312
STKc_MAPKKK_Bck1_lik	cd06629	1.9e-10	12	233
STKc_CDK_like	cd07829	3.1e-20	12	233
STKc_MAK_like	cd07830	8.4e-14	12	233
STKc_CDK1_like	cd07835	3.1e-07	12	233
STKc_MOK	cd07831	4.4e-14	12	233
STKc_CDK4_6_like	cd07838	7.5e-14	12	233
STKc_CDK9_like	cd07840	7e-16	12	233
STKc_ERK5	cd07855	2e-10	12	265
STKc_MEKK1_plant	cd06632	2.1e-14	13	233
PK_STRAD	cd08216	0.00015	13	249
STKc_SLK_like	cd06611	5.8e-12	14	250
STKc_p70S6K	cd05584	4.1e-18	15	307
STKc_MEKK4	cd06626	5.3e-13	15	233
PTKc	cd00192	2.8e-12	16	232
PTKc_Ack_like	cd05040	6e-09	16	234
PTKc_c-ros	cd05044	0.00023	16	233
PTKc_Tie	cd05047	5.2e-05	16	229
PTKc_Syk_like	cd05060	3.2e-07	16	219
PTKc_Fes	cd05084	0.00012	16	233
PTKc_Fer	cd05085	1.5e-05	16	233
PTKc_Syk	cd05116	2.7e-05	16	233
PTKc_Fes_like	cd05041	4.5e-09	16	233
STKc_PKC	cd05570	6.1e-16	16	281
STKc_PKB	cd05571	4.6e-13	16	307
STKc_SGK	cd05575	7.5e-09	16	287
STKc_RSK_N	cd05582	1e-12	16	281
STKc_aPKC	cd05588	6.1e-10	16	309
STKc_nPKC_eta	cd05590	7.6e-11	16	306
STKc_nPKC_epsilon	cd05591	9.1e-11	16	297
STKc_nPKC_theta_delt	cd05592	3.8e-15	16	307
STKc_PKB_gamma	cd05593	1.1e-09	16	326
STKc_PKB_alpha	cd05594	6e-11	16	311
STKc_PKB_beta	cd05595	6.7e-10	16	301
STKc_SGK1	cd05602	3.1e-06	16	314
STKc_SGK2	cd05603	2.4e-08	16	313
STKc_SGK3	cd05604	5.1e-06	16	289
STKc_aPKC_zeta	cd05617	3.4e-09	16	309
STKc_aPKC_iota	cd05618	1.2e-07	16	309
STKc_nPKC_theta	cd05619	4.6e-12	16	310
STKc_nPKC_delta	cd05620	1.8e-07	16	314
STKc_beta_ARK	cd05606	1.4e-07	17	253
STKc_GRK3	cd05633	8.3e-07	17	262
STKc_Nek9	cd08221	5.3e-12	17	233
PKc	cd00180	3.7e-56	18	231
PTKc_Aatyk	cd05042	1.1e-06	18	216
PTKc_Zap-70	cd05115	2.7e-05	18	236
STKc_AGC	cd05123	9e-40	18	233
STKc_GRK	cd05577	6.8e-12	18	249
STKc_cGK_PKG	cd05572	3.7e-17	18	239
STKc_MAST_like	cd05579	1.9e-19	18	238
STKc_Sck1_like	cd05586	4.7e-07	18	362
STKc_YPK1_like	cd05585	5.8e-09	18	295
STKc_GRK1	cd05608	2.5e-08	18	253
STKc_GRK7	cd05607	1.7e-06	18	258
STKc_Rim15_like	cd05611	1.5e-07	20	235
Pkinase	pfam00069	3.9e-60	12	233
POLO_box	pfam00659	1e-14	860	924
S_TKc	smart00220	4.9e-62	2	233
Pkinase_Tyr	pfam07714	2e-15	12	233
TyrKc	smart00219	3.1e-12	12	233
STYKc	smart00221	2.6e-49	12	233
KIND	smart00750	8.1e-06	69	241

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs17012739	Polymorphism	p.GLU798ASP	N/A
dbSNP	rs3811740	Polymorphism	p.SER200THR	N/A
dbSNP	rs61735390	Polymorphism	p.THR796MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258