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Results for the Protein: NP_001191818
325910904
217

aldehyde dehydrogenase, mitochondrial isoform 2 precursor [Homo sapiens]

Known Diseases associated with this Protein:
  ALCOHOL DEPENDENCE, PROTECTION AGAINST, INCLUDED;;
  ALCOHOL SENSITIVITY, ACUTE
  HANGOVER, SUSCEPTIBILITY TO, INCLUDED;;|
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Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

ALDH_PutA-P5CDH - cd07125
COG4230 - COG4230
ALDH_RL0313 - cd07148
ALDH_KGSADH-like - cd07084
ALDH_PutA-P5CDH-RocA - cd07124
ALDH_P5CDH - cd07083
ALDH_F16 - cd07111
ALDH_F1AB_F2_RALDH1 - cd07141
ALDH_CALDH_CalB - cd07133
ALDH_F2BC - cd07142
ALDH_F1-2_Ald2-like - cd07091
ALDH_F1L_FTFDH - cd07140
ALDH_F11_NP-GAPDH - cd07082
PutA - COG1012
ALDH_KGSADH-YcbD - cd07097
ALDH_F6_MMSDH - cd07085
ALDH_ACDHII-AcoD - cd07116
ALDH_ACDHII_AcoD-lik - cd07559
ALDH_StaphAldA1 - cd07117
ALDH_AldA_AN0554 - cd07143
ALDH_F7_AASADH-like - cd07086
ALDH_ALD2-YMR170C - cd07144
ALDH_AldA-Rv0768 - cd07139
ALDH_F7_AASADH - cd07130
ALDH_AldH-CAJ73105 - cd07131
ALDH_CddD_SSP0762 - cd07138
ALDH_MaoC-N - cd07128
ALDH_F12_P5CDH - cd07126
ALDH_PADH_NahF - cd07113
ALDH_BADH-GbsA - cd07119
ALDH_LactADH-AldA - cd07088
ALDH_HBenzADH - cd07151
ALDH_SaliADH - cd07105
Aldedh - pfam00171
ALDH_F3FHI - cd07137
ALDH_BenzADH-like - cd07104
ALDH - cd07078
ALDH-SF - cd06534
ALDH_GABALDH-PuuC - cd07112
ALDH_AlkH-like - cd07134
ALDH_y4uC - cd07149
ALDH_VaniDH_like - cd07150
ALDH_F21_RNP123 - cd07147
ALDH_F21_LactADH-lik - cd07094
ALDH_LactADH_F420-Bi - cd07145
ALDH_PhpJ - cd07146
ALDH_DhaS - cd07114
ALDH_F10_BADH - cd07110
ALDH_F14-YMR110C - cd07135
ALDH_HMSADH_HapE - cd07115
ALDH_CddD-AldA-like - cd07089
ALDH_PsfA-ACA09737 - cd07120
ALDH_F8_HMSADH - cd07093
ALDH_F9_TMBADH - cd07090
ALDH_ABALDH-YdcW - cd07092
ALDH_F5_SSADH_GabD - cd07103
ALDH_PhdK-like - cd07107
ALDH_AldA-AAD23400 - cd07106
ALDH_MGR_2402 - cd07108
ALDH_AAS00426 - cd07109
ALDH_SSADH2_GabD2 - cd07101
ALDH_EDX86601 - cd07102
ALDH_F15-22 - cd07098
ALDH_DDALDH - cd07099
ALDH_SNDH - cd07118
ALDH_BenzADH - cd07152
ALDH_F3-13-14_CALDH- - cd07087
ALDH_F4-17_P5CDH - cd07123
ALDH_SSADH1_GabD1 - cd07100
ALDH_F3AB - cd07132
ALDH_YwdH-P39616 - cd07136
ALDH_SGSD_AstD - cd07095




Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
ALDH_PutA-P5CDHcd071257.2e-161470
ALDH_RL0313cd071484.9e-152463
ALDH_KGSADH-likecd070842.8e-0913463
ALDH_PutA-P5CDH-RocAcd071244.6e-4315465
ALDH_P5CDHcd070832.2e-3719465
ALDH_F16cd071117e-12926463
ALDH_F1AB_F2_RALDH1cd0714131464
ALDH_CALDH_CalBcd071334e-1832463
ALDH_F1-2_Ald2-likecd0709134463
ALDH_F1L_FTFDHcd071408.5e-15034465
ALDH_F2BCcd071421.6e-27034463
ALDH_F11_NP-GAPDHcd070821.3e-3236464
ALDH_F6_MMSDHcd070859.3e-3037465
ALDH_KGSADH-YcbDcd070977.6e-8937463
ALDH_ACDHII-AcoDcd071165.8e-12137465
PutACOG10125.7e-19437468
ALDH_StaphAldA1cd071179.1e-14938465
ALDH_ACDHII_AcoD-likcd075591.9e-16038465
ALDH_F7_AASADH-likecd070861.6e-4839463
ALDH_F7_AASADHcd071304e-1939412
ALDH_AldH-CAJ73105cd071311.3e-7839466
ALDH_CddD_SSP0762cd071381.7e-11139463
ALDH_AldA-Rv0768cd071394.1e-10639463
ALDH_ALD2-YMR170Ccd071449.5e-20939465
ALDH_AldA_AN0554cd071433.5e-23239465
ALDH_LactADH-AldAcd070881.3e-9440463
ALDH_PADH_NahFcd071131.2e-8440465
ALDH_BADH-GbsAcd071195.3e-16740461
ALDH_F12_P5CDHcd071261.3e-0540451
ALDH_MaoC-Ncd071283e-0640457
ALDH_HBenzADHcd071511.2e-4543465
ALDH_SaliADHcd071052.2e-4644463
ALDH_F3FHIcd071378.7e-1445463
ALDH_BenzADH-likecd071041.3e-9047463
ALDH-SFcd065345.9e-20348463
ALDHcd070786.1e-21448463
ALDH_GABALDH-PuuCcd071124.5e-16851463
ALDH_AlkH-likecd071342.5e-2151463
ALDH_F21_LactADH-likcd070941.8e-7254463
ALDH_LactADH_F420-Bicd071453.2e-7954463
ALDH_PhpJcd071461.7e-3954463
ALDH_F21_RNP123cd071477.8e-3254463
ALDH_y4uCcd071491.6e-6354463
ALDH_VaniDH_likecd071504.1e-9754463
ALDH_F9_TMBADHcd070903.1e-14656466
ALDH_ABALDH-YdcWcd070922.1e-11756463
ALDH_F8_HMSADHcd070931.7e-15056463
ALDH_F5_SSADH_GabDcd071031.7e-10556463
ALDH_PhdK-likecd071079e-9956465
ALDH_MGR_2402cd071088.4e-9456463
ALDH_AldA-AAD23400cd071062.2e-8456463
ALDH_AAS00426cd071091e-13256463
ALDH_HMSADH_HapEcd071155.1e-19956465
ALDH_DhaScd071141.8e-15956463
ALDH_PsfA-ACA09737cd071206.3e-7456463
ALDH_F10_BADHcd071106.9e-13556463
ALDH_CddD-AldA-likecd070895.1e-12056463
ALDH_F14-YMR110Ccd071353.6e-1856463
ALDH_F15-22cd070981.3e-3057465
ALDH_DDALDHcd070992.4e-5257463
ALDH_EDX86601cd071021.3e-4557463
ALDH_SSADH2_GabD2cd071012.8e-2957463
ALDH_SNDHcd071181.1e-10759463
ALDH_BenzADHcd071523e-4662463
ALDH_F3-13-14_CALDH-cd070871.6e-1863463
ALDH_F4-17_P5CDHcd071236.3e-1163443
ALDH_SSADH1_GabD1cd071001.4e-4464463
ALDH_F3ABcd071326.9e-1472456
ALDH_YwdH-P39616cd071361.1e-1472464
ALDH_SGSD_AstDcd070959e-1894445
COG4230COG42301.2e-062470
Aldedhpfam001717.8e-20945461

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
dbSNPrs671 Polymorphismp.GLU457LYSN/A
OMIM100650.0001 Diseasep.GLU457LYSALCOHOL SENSITIVITY, ACUTE||ALCOHOL DEPENDENCE, PROTECTION AGAINST, INCLUDED;;||HANGOVER, SUSCEPTIBILITY TO, INCLUDED;;|



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