Home News About DMDM Database Statistics Research Publications Contact  

Results for the Protein: P25092
311033390

GUC2C_HUMAN RecName: Full=Heat-stable enterotoxin receptor; Short=STA receptor; Short=hSTAR; AltName: Full=Guanylyl cyclase C; Short=GC-C; AltName: Full=Intestinal guanylate cyclase; Flags: Precursor

Known Diseases associated with this Protein:
  DIARRHEA 6
  DIARRHEA 6 (DIAR6)
  MECONIUM ILEUS
  MECONIUM ILEUS (MECIL)
4
9
2
1
10
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

PBP1_GC_C_enterotoxi - cd06369
PBP1_NPR_GC_like - cd06352
PBP1_NPR_like - cd06373
PBP1_ABC_transporter - cd04509
ANF_receptor - pfam01094
PTKc_PDGFR_alpha - cd05105
PTKc_Kit - cd05104
PTKc_PDGFR - cd05055
PTKc_DDR - cd05051
PTKc_EGFR_like - cd05057
PTKc_FGFR1 - cd05098
PTKc_FGFR2 - cd05101
PTKc_FAK - cd05056
PTKc_DDR2 - cd05095
PTKc_FGFR4 - cd05099
PTKc_InsR - cd05061
PTK_CCK4 - cd05046
PTKc_Axl_like - cd05035
PTKc_Abl - cd05052
PKc - cd00180
PTKc_EphR_A2 - cd05063
PTKc_Met_Ron - cd05058
STKc_TAO - cd06607
STKc_PAK - cd06614
PTKc_Fer - cd05085
PTKc_Btk_Bmx - cd05113
PTKc_TrkB - cd05093
PTKc_Tec_Rlk - cd05114
PTKc_Ror2 - cd05091
STKc_MST3 - cd06641
STKc_MST4 - cd06640
PTKc_Frk_like - cd05068
PTKc_Yes - cd05069
PTKc_Fyn_Yrk - cd05070
PTKc_EphR_A10 - cd05064
PTKc_Lck_Blk - cd05067
PTKc_Ror1 - cd05090
PTKc_Src - cd05071
PTKc_Tie1 - cd05089
PTKc_Hck - cd05073
PTKc_Lyn - cd05072
STKc_PDK1 - cd05581
PTKc_Itk - cd05112
PTKc_EphR_B - cd05065
PTKc_Jak1_rpt2 - cd05079
STKc_PAK_II - cd06648
PTKc_Chk - cd05083
PTKc_Tie2 - cd05088
SPS1 - COG0515
PTKc_Tyro3 - cd05074
PTKc_Zap-70 - cd05115
PTKc_Csk - cd05082
PTKc_Syk - cd05116
PTKc_EphR - cd05033
PTKc_Csk_like - cd05039
PTKc_RET - cd05045
PTKc_Fes - cd05084
PTKc_FGFR - cd05053
PTKc_IGF-1R - cd05062
STKc_OSR1_SPAK - cd06610
STKc_STK25-YSK1 - cd06642
STKc_Nek8 - cd08220
STKc_MAP4K3_like - cd06613
PTKc_ALK_LTK - cd05036
PTKc_Jak2_Jak3_rpt2 - cd05081
PTK_Jak_rpt1 - cd05037
TyrKc - smart00219
STYKc - smart00221
PTKc_Tyk2_rpt2 - cd05080
PKc_STE - cd05122
PTKc_Musk - cd05050
PTKc_EphR_A - cd05066
PTKc_TrkC - cd05094
PTKc_TrkA - cd05092
PTKc_Jak_rpt2 - cd05038
PTKc_Trk - cd05049
PTKc_InsR_like - cd05032
Pkinase - pfam00069
PTKc_Ror - cd05048
PTKc_Src_like - cd05034
PTKc_Srm_Brk - cd05148
STKc_Nek - cd08215
PTKc_Tie - cd05047
PKc_MAPKK_plant_like - cd06623
STKc_MAPKKK - cd06606
Pkinase_Tyr - pfam07714
PTKc_Ack_like - cd05040
PTKc_Syk_like - cd05060
PTKc_Fes_like - cd05041
STKc_MEKK4 - cd06626
STKc_MST3_like - cd06609
S_TKc - smart00220
PTKc - cd00192
STKc_MST1_2 - cd06612
STKc_YSK4 - cd06631
STKc_Cdc7_like - cd06627
PTKc_Tec_like - cd05059
PTKc_c-ros - cd05044
CyaA - COG2114
CYCc - smart00044
Guanylate_cyc - pfam00211
CHD - cd07302
Nucleotidyl_cyc_III - cd07556


Swiss-Prot Protein: P25092
Identical to: NP_004954
   Default View:































































































Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
PBP1_GC_C_enterotoxicd063696e-27835415
PBP1_ABC_transportercd045099.7e-1636382
PBP1_NPR_GC_likecd063521.7e-9336407
PBP1_NPR_likecd063737.7e-0636407
PTKc_PDGFR_alphacd051050.00038351751
PTKc_Kitcd051040.0001371749
PTKc_PDGFRcd050554e-06390749
PTKc_DDRcd050510.00027455747
PTKc_EGFR_likecd050573.6e-06455754
PTKc_FGFR1cd050982.4e-05459756
PTKc_FGFR2cd051011e-05460756
PTKc_FAKcd050567.4e-07461753
PTKc_DDR2cd050950.00056462747
PTKc_FGFR4cd050991.5e-06464774
PTKc_InsRcd050610.00063468760
PTK_CCK4cd050463.3e-06470747
PTKc_Axl_likecd050354.2e-05477749
PKccd001803.9e-28479745
PTKc_Ablcd050521.1e-07479749
PTKc_EphR_A2cd050632.6e-06480749
PTKc_Met_Roncd050589.8e-05480751
STKc_TAOcd066070.00053481787
PTKc_Fercd050859.1e-06482747
STKc_PAKcd066145.1e-08482723
PTKc_EphR_A10cd050641.9e-06483749
PTKc_Lck_Blkcd050672e-06483748
PTKc_Yescd050695.6e-06483748
PTKc_Fyn_Yrkcd050704.9e-05483748
PTKc_Srccd050716.2e-05483750
PTKc_Lyncd050722.4e-07483748
PTKc_Hckcd050731e-07483748
PTKc_Tie1cd050892e-05483766
PTKc_Ror1cd050906.3e-05483748
PTKc_Ror2cd050917.1e-06483748
PTKc_TrkBcd050937.1e-06483754
PTKc_Btk_Bmxcd051134.5e-10483746
PTKc_Tec_Rlkcd051145.5e-08483746
PTKc_Frk_likecd050684.7e-08483748
STKc_MST4cd066400.00016483772
STKc_MST3cd066413.9e-05483772
PTKc_EphR_Bcd050655.2e-07484749
PTKc_Jak1_rpt2cd050797.9e-05484749
PTKc_Itkcd051127.3e-09484746
STKc_PDK1cd055810.00017484749
PTKc_Chkcd050831.7e-07485748
STKc_PAK_IIcd066480.00068485765
PTKc_Tie2cd050883.7e-06486776
PTKc_Tyro3cd050740.00011487749
PTKc_Cskcd050821.4e-07487748
PTKc_Zap-70cd051157.7e-05487750
SPS1COG05154.2e-05487916
PTKc_EphRcd050339.8e-08489749
PTKc_Csk_likecd050392.1e-08489748
PTKc_Sykcd051164.7e-05489750
PTKc_RETcd050451.5e-05490752
PTKc_Fescd050845.5e-07490747
PTKc_FGFRcd050532.3e-06491750
PTKc_IGF-1Rcd050627.2e-05491747
STKc_OSR1_SPAKcd066101.4e-06492738
STKc_STK25-YSK1cd066428e-05492772
PTKc_ALK_LTKcd050367.1e-06493747
PTK_Jak_rpt1cd050376.8e-05493746
PTKc_Jak2_Jak3_rpt2cd050812.6e-08493749
STKc_MAP4K3_likecd066137e-05493749
STKc_Nek8cd082200.00065493750
PTKc_Muskcd050506e-07494747
PTKc_EphR_Acd050661.1e-06494749
PTKc_Tyk2_rpt2cd050806.1e-07494754
PKc_STEcd051225.1e-09494738
PTKc_Jak_rpt2cd050387.4e-09495749
PTKc_TrkAcd050926.1e-06495747
PTKc_TrkCcd050940.00014495754
PTKc_InsR_likecd050324.1e-08496747
PTKc_Trkcd050494.1e-08496747
PTKc_Src_likecd050342.1e-09497748
PTKc_Rorcd050484.7e-08497748
PTKc_Srm_Brkcd051481e-08497748
STKc_Nekcd082151.9e-06497750
PTKc_Tiecd050473.6e-05498750
PKc_MAPKK_plant_likecd066234.3e-05498743
STKc_MAPKKKcd066062.4e-07499738
PTKc_Ack_likecd050402e-09501747
PTKc_Fes_likecd050412.4e-10501747
PTKc_Syk_likecd050605.2e-07501750
STKc_MST3_likecd066090.00018501759
STKc_MEKK4cd066267.9e-05501739
PTKccd001924.9e-11504746
STKc_MST1_2cd066122.4e-05506739
STKc_Cdc7_likecd066273.4e-05507741
STKc_YSK4cd066310.00023507739
PTKc_Tec_likecd050591.5e-10510746
PTKc_c-roscd050444.4e-05517747
CHDcd073025.3e-688221000
Nucleotidyl_cyc_IIIcd075561.5e-39822963
ANF_receptorpfam010946.3e-4653386
Pkinasepfam000692.5e-10497745
CyaACOG21141.3e-277751010
Guanylate_cycpfam002113.4e-1028151001
TyrKcsmart002193e-12494745
STYKcsmart002212.6e-06494747
Pkinase_Tyrpfam077142.3e-14500745
S_TKcsmart002202.7e-09502749
CYCcsmart000441.4e-104788981

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_042223Polymorphismp.ARG114GLNN/A
Swiss-ProtVAR_042224Polymorphismp.ARG464LEUN/A
Swiss-ProtVAR_068174Diseasep.ASP387GLYMeconium ileus (MECIL)
Swiss-ProtVAR_042221Polymorphismp.CYS30ARGN/A
Swiss-ProtVAR_042227Polymorphismp.GLN1045ARGN/A
Swiss-ProtVAR_042225Polymorphismp.GLU610LYSN/A
Swiss-ProtVAR_042222Polymorphismp.GLY61ARGN/A
Swiss-ProtVAR_042226Polymorphismp.ILE859VALN/A
dbSNPrs1420635 Polymorphismp.PHE281LEUN/A
Swiss-ProtVAR_067724Diseasep.SER840ILEDiarrhea 6 (DIAR6)
Swiss-ProtVAR_042228Polymorphismp.TYR1072CYSN/A
OMIM601330.0002 Diseasep.ASP387GLYMECONIUM ILEUS
OMIM601330.0001 Diseasep.SER840ILEDIARRHEA 6



   |   1000 Hilltop Circle, Baltimore, MD 21250   |   Department of Biological Sciences   |   Phone: 410-455-2258