Results for the protein: O94911

Results for the Protein: O94911

115503766

10351

ABCA8

NCBI, UniProt

ABCA8_HUMAN RecName: Full=ATP-binding cassette sub-family A member 8

			0 12 0 9 3

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Swiss-Prot Protein: O94911

Identical to: NP_009099

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Ttg2A	COG1127	4e-11	468	704
ABCC_TAP	cd03248	2.1e-05	470	653
PstB	COG1117	1.3e-07	473	667
CcmA	COG1131	1.3e-38	476	753
ABCG_EPDR	cd03213	6.5e-12	477	657
Uup	COG0488	0.00036	477	858
CbiO	COG1122	1.4e-11	477	682
ABCC_MRP_domain2	cd03244	2.1e-07	478	659
ABCC_bacteriocin_exp	cd03245	9.3e-11	478	657
ABC_CysA_sulfate_imp	cd03296	1.8e-06	478	668
GlnQ	COG1126	5.1e-12	478	676
ABC_MetN_methionine_	cd03258	2.4e-13	479	665
OpuBA	COG1125	2e-09	479	747
SalX	COG1136	8.1e-15	479	660
AbcC	COG1135	5.8e-10	479	774
ABC_KpsT_Wzt	cd03220	1.6e-13	480	657
ABCC_MRP_Like	cd03228	5.4e-15	480	652
ABC_Class3	cd03229	2.5e-18	480	652
ABC_DR_subfamily_A	cd03230	5.4e-39	480	653
ABCC_Protease_Secret	cd03246	5.3e-08	480	635
ABCC_cytochrome_bd	cd03247	1.4e-10	480	657
ABC_MTABC3_MDL1_MDL2	cd03249	4e-07	480	675
ABCC_MRP_domain1	cd03250	4.7e-09	480	652
ABCC_MsbA	cd03251	8e-09	480	673
ABCC_Glucan_exporter	cd03254	6.3e-08	480	667
ABC_MJ0796_LolCDE_Ft	cd03255	3.7e-15	480	653
ABCC_Hemolysin	cd03252	2.8e-06	480	675
ABC_PhnC_transporter	cd03256	1.2e-09	480	661
ABC_PstB_phosphate_t	cd03260	2.6e-11	480	662
ABC_Org_Solvent_Resi	cd03261	5.8e-14	480	670
ABC_HisP_GlnQ	cd03262	6.1e-12	480	653
ABCC_ATM1_transporte	cd03253	8.5e-08	480	675
ABC_drug_resistance_	cd03264	6.4e-14	480	657
ABC_DrrA	cd03265	2.4e-18	480	663
ABC_NatA_sodium_expo	cd03266	1.8e-13	480	657
ABC_BcrA_bacitracin_	cd03268	3.3e-14	480	657
ABC_subfamily_A	cd03263	6.6e-56	480	663
ABC_FtsE_transporter	cd03292	4.5e-10	480	653
ABC_Pro_Gly_Betaine	cd03294	1.1e-09	480	660
ABC_OpuCA_Osmoprotec	cd03295	8.2e-09	480	668
ABC_ATPase	cd00267	2.4e-33	481	652
ABC_Iron-Siderophore	cd03214	1e-10	481	657
ABC_cobalt_CbiO_doma	cd03225	6.2e-17	481	652
ABC_cobalt_CbiO_doma	cd03226	5.5e-11	481	654
ABC_ThiQ_thiamine_tr	cd03298	2.5e-09	492	657
ModF	COG1119	2.6e-10	1219	1462
MglA	COG1129	2.9e-06	1232	1574
COG1123	COG1123	9.7e-09	1235	1574
YhbG	COG1137	1.7e-13	1235	1475
CcmA	COG1131	2.5e-78	1236	1557
TauB	COG1116	3.6e-12	1237	1506
DppF	COG1124	1.4e-09	1237	1486
TagH	COG1134	2.8e-11	1237	1481
FepC	COG1120	3.6e-11	1238	1491
ABC_NikE_OppD_transp	cd03257	1.4e-13	1239	1460
ABC_Carb_Monos_I	cd03216	3.8e-17	1240	1461
ABC_YhbG	cd03218	1.3e-11	1240	1475
ABC_KpsT_Wzt	cd03220	4.3e-16	1240	1460
ABCF_EF-3	cd03221	5.7e-09	1240	1455
ABCC_MRP_Like	cd03228	3.8e-13	1240	1455
ABC_Class3	cd03229	5.8e-16	1240	1455
ABC_DR_subfamily_A	cd03230	6.4e-72	1240	1456
ABC_MJ0796_LolCDE_Ft	cd03255	1.8e-12	1240	1456
ABC_Carb_Solutes_lik	cd03259	1.6e-15	1240	1460
ABC_drug_resistance_	cd03264	3e-26	1240	1460
ABC_DrrA	cd03265	3.3e-35	1240	1466
ABC_NatA_sodium_expo	cd03266	3.5e-17	1240	1460
ABC_NatA_like	cd03267	1.9e-15	1240	1460
ABC_BcrA_bacitracin_	cd03268	1.7e-24	1240	1460
ABC_subfamily_A	cd03263	4e-94	1240	1466
ABC_NrtD_SsuB_transp	cd03293	4.9e-15	1240	1464
ABC_MalK_N	cd03301	3.2e-11	1240	1460
ABC_PotA_N	cd03300	6.6e-09	1240	1470
ABC_ModC_molybdenum_	cd03297	5.1e-13	1240	1460
ABC_ATPase	cd00267	6.3e-52	1241	1455
ABC_Iron-Siderophore	cd03214	5.2e-14	1241	1460
ABC_Carb_Monos_II	cd03215	1.2e-10	1247	1456
ABCG_PDR_domain1	cd03233	8.4e-08	1247	1460
PhnK	COG1101	1.8e-08	1247	1489
ABCG_White	cd03234	1.1e-09	1248	1460
ABCC_CFTR2	cd03289	0.00032	1248	1526
CbiO	COG1122	1.6e-11	1248	1484
ABC_cobalt_CbiO_doma	cd03225	5.1e-19	1250	1455
ABC_CysA_sulfate_imp	cd03296	1.6e-08	1250	1476
ZnuC	COG1121	6.2e-12	1250	1491
ABC_RNaseL_inhibitor	cd03222	4.2e-07	1252	1478
ABCG_PDR_domain2	cd03232	3.3e-06	1252	1435
ABC_CcmA_heme_export	cd03231	3.5e-08	1254	1453
LivF	COG0410	6.7e-13	1254	1475
ABCD_peroxisomal_ALD	cd03223	0.00071	1256	1456
DppD	COG0444	1.9e-08	1256	1529
ABC_putative_ATPase	cd03269	1.3e-27	1257	1460
ABC_RNaseL_inhibitor	cd03237	8.4e-07	1258	1470
ABC_FeS_Assembly	cd03217	2.2e-07	1259	1470
ABC_Metallic_Cations	cd03235	2.9e-11	1259	1460
ABC_RNaseL_inhibitor	cd03236	1.3e-05	1259	1503
CysA	COG1118	2.7e-09	1260	1563
LivG	COG0411	2.9e-13	1261	1471
ABC_ModC_like	cd03299	1.1e-09	1262	1474
ABC_TM1139_LivF_bran	cd03224	2.2e-17	1263	1468
sufC	COG0396	4.9e-09	1263	1481
ABC_Mj1267_LivG_bran	cd03219	6e-16	1265	1467
ABCC_NFT1	cd03369	0.001	1267	1462
SunT	COG2274	0.00036	21	676
CydC	COG4987	0.00019	251	677
CydD	COG4988	9e-06	266	678
COG4181	COG4181	9.3e-08	475	657
ProV	COG4175	0.00016	476	714
COG3638	COG3638	1.4e-09	477	691
FtsE	COG2884	5.8e-08	479	643
ThiQ	COG3840	1.6e-08	479	663
NatA	COG4555	1.6e-15	479	687
CeuD	COG4604	1.4e-05	480	659
ModC	COG4148	1.5e-05	497	742
ABC_tran	pfam00005	0.00059	523	605
ArpD	COG4618	0.00071	1069	1489
PhnK	COG4107	0.00018	1234	1485
PotA	COG3842	3.4e-10	1235	1577
COG3845	COG3845	0.00019	1236	1578
SapF	COG4167	3.3e-05	1236	1482
AppF	COG4608	2.6e-08	1236	1495
PhnL	COG4778	7.7e-06	1236	1458
MalK	COG3839	1.7e-10	1237	1559
COG4586	COG4586	1.7e-13	1237	1559
COG4152	COG4152	5.1e-15	1238	1560
TauB	COG4525	5.8e-09	1238	1504
NatA	COG4555	1.5e-31	1239	1490
COG4619	COG4619	2.3e-07	1248	1470
CcmA	COG4133	2.2e-10	1249	1456
ArtP	COG4161	6.9e-09	1249	1476
COG4674	COG4674	4.4e-08	1252	1479
COG4136	COG4136	1.4e-05	1255	1455
HisP	COG4598	2e-06	1258	1478
COG4559	COG4559	1.5e-06	1259	1499
BtuD	COG4138	0.00034	1260	1492
ABC_tran	pfam00005	9.4e-22	1290	1406
AAA	smart00382	6.1e-11	508	652
AAA	smart00382	0.00069	1275	1455

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs62638729	Polymorphism	p.ALA253GLY	N/A
dbSNP	rs35621847	Polymorphism	p.ALA416VAL	N/A
dbSNP	rs16973424	Polymorphism	p.CYS680GLY	N/A
dbSNP	rs35403175	Polymorphism	p.GLY1430SER	N/A
Swiss-Prot	VAR_027591	Polymorphism	p.GLY331SER	N/A
Swiss-Prot	VAR_048131	Polymorphism	p.LEU619ARG	N/A
dbSNP	rs77734018	Polymorphism	p.PHE419SER	N/A
dbSNP	rs16973446	Polymorphism	p.THR256ALA	N/A
dbSNP	rs35643726	Polymorphism	p.THR12SER	N/A
dbSNP	rs76430844	Polymorphism	p.THR632SER	N/A
Swiss-Prot	VAR_027592	Polymorphism	p.TYR489PHE	N/A
dbSNP	rs79398827	Polymorphism	p.VAL1082MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258