Results for the protein: P19544

Results for the Protein: P19544

139778

7490

WT1

NCBI, UniProt

WT1_HUMAN RecName: Full=Wilms tumor protein; AltName: Full=WT33

Known Diseases associated with this Protein:
  DENYS-DRASH SYNDROME (DDS)
  FRASIER SYNDROME (FS)
  NEPHROTIC SYNDROME 4 (NPHS4)
  WILMS TUMOR 1 (WT1)

37

3

0

0

40

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Default View: ZnF_C2H2 - smart00355	Swiss-Prot Protein: P19544 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
ZnF_C2H2	smart00355	0.00069	383	405
ZnF_C2H2	smart00355	0.00065	414	438

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_043798	Polymorphism	p.ALA131THR	N/A
Swiss-Prot	VAR_007745	Disease	p.ARG366CYS	Wilms tumor 1 (WT1)
Swiss-Prot	VAR_015053	Disease	p.ARG312GLN	Nephrotic syndrome 4 (NPHS4)
Swiss-Prot	VAR_015061	Disease	p.ARG394GLN	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_007746	Disease	p.ARG366HIS	Wilms tumor 1 (WT1)
Swiss-Prot	VAR_043802	Disease	p.ARG366LEU	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_043807	Disease	p.ARG394LEU	Wilms tumor 1 (WT1)
Swiss-Prot	VAR_043808	Disease	p.ARG394PRO	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_007750	Disease	p.ARG394TRP	Wilms tumor 1 (WT1)
Swiss-Prot	VAR_007751	Disease	p.ASP396ASN	Nephrotic syndrome 4 (NPHS4)
Swiss-Prot	VAR_007752	Disease	p.ASP396GLY	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_043809	Disease	p.ASP396TYR	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_015058	Disease	p.CYS385ARG	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_043805	Disease	p.CYS388ARG	Nephrotic syndrome 4 (NPHS4)
Swiss-Prot	VAR_043799	Disease	p.CYS355GLY	Wilms tumor 1 (WT1)
Swiss-Prot	VAR_007744	Disease	p.CYS360GLY	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_015059	Disease	p.CYS388PHE	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_007743	Disease	p.CYS330TYR	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_015055	Disease	p.CYS355TYR	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_043800	Disease	p.CYS360TYR	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_043806	Disease	p.CYS388TYR	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_043803	Disease	p.GLN369PRO	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_007741	Disease	p.GLY253ALA	Wilms tumor 1 (WT1)
Swiss-Prot	VAR_043804	Disease	p.GLY379CYS	Nephrotic syndrome 4 (NPHS4)
Swiss-Prot	VAR_015057	Disease	p.HIS377ARG	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_043812	Disease	p.HIS405ARG	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_007747	Disease	p.HIS373GLN	Wilms tumor 1 (WT1)
Swiss-Prot	VAR_043810	Disease	p.HIS397PRO	Nephrotic syndrome 4 (NPHS4)
Swiss-Prot	VAR_015056	Disease	p.HIS373TYR	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_007748	Disease	p.HIS377TYR	Nephrotic syndrome 4 (NPHS4)
Swiss-Prot	VAR_043811	Disease	p.HIS401TYR	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_058021	Polymorphism	p.LEU281PRO	N/A
Swiss-Prot	VAR_015062	Disease	p.LEU398PRO	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_015054	Disease	p.MET342ARG	Denys-Drash syndrome (DDS)
Swiss-Prot	VAR_043801	Disease	p.PHE364LEU	Nephrotic syndrome 4 (NPHS4)
Swiss-Prot	VAR_007749	Disease	p.PHE383LEU	Nephrotic syndrome 4 (NPHS4)
Swiss-Prot	VAR_015060	Disease	p.PHE392LEU	Frasier syndrome (FS)
Swiss-Prot	VAR_007739	Disease	p.PRO181SER	Wilms tumor 1 (WT1)
Swiss-Prot	VAR_007740	Disease	p.SER223ASN	Wilms tumor 1 (WT1)
Swiss-Prot	VAR_007742	Polymorphism	p.SER273GLY	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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