Results for the protein: O14920

Results for the Protein: O14920

14285497

3551

IKBKB

NCBI, UniProt

IKKB_HUMAN RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit beta; Short=I-kappa-B-kinase beta; Short=IKK-B; Short=IKK-beta; Short=IkBKB; AltName: Full=I-kappa-B kinase 2; Short=IKK2; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase beta; Short=NFKBIKB

			0 7 0 1 6

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Default View: Pkinase_Tyr - pfam07714 TyrKc - smart00219 STYKc - smart00221 S_TKc - smart00220 IKKbetaNEMObind - pfam12179	Swiss-Prot Protein: O14920 Identical to: NP_001547 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STYKc	smart00221	1.2e-55	15	287
TyrKc	smart00219	1.9e-13	15	307
S_TKc	smart00220	4.8e-54	25	312
IKKbetaNEMObind	pfam12179	1e-21	705	742

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_035626	Polymorphism	p.ALA360SER	N/A
Swiss-Prot	VAR_040569	Polymorphism	p.ALA710THR	N/A
Swiss-Prot	VAR_051628	Polymorphism	p.ALA736THR	N/A
dbSNP	rs2272736	Polymorphism	p.ARG526GLN	N/A
Swiss-Prot	VAR_021124	Polymorphism	p.ARG554TRP	N/A
Swiss-Prot	VAR_040567	Polymorphism	p.GLN369ARG	N/A
Swiss-Prot	VAR_040570	Polymorphism	p.PHE734LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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