Results for the protein: Q16363

Results for the Protein: Q16363

292495093

3910

LAMA4

NCBI, UniProt

LAMA4_HUMAN RecName: Full=Laminin subunit alpha-4; AltName: Full=Laminin-14 subunit alpha; AltName: Full=Laminin-8 subunit alpha; AltName: Full=Laminin-9 subunit alpha; Flags: Precursor

Known Diseases associated with this Protein:
CARDIOMYOPATHY, DILATED 1JJ (CMD1JJ)

1

9

0

0

10

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: EGF_Lam - cd00055 Laminin_EGF - pfam00053 EGF_Lam - smart00180 Laminin_I - pfam06008 Laminin_II - pfam06009 LamG - cd00110 LamG - smart00282 Laminin_G_2 - pfam02210 Laminin_G_1 - pfam00054	Swiss-Prot Protein: Q16363 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
EGF_Lam	cd00055	4.4e-14	131	185
EGF_Lam	cd00055	5.8e-18	186	239
LamG	cd00110	1.7e-28	835	1012
LamG	cd00110	6.3e-32	1049	1208
LamG	cd00110	7.8e-19	1236	1377
LamG	cd00110	8e-42	1469	1624
LamG	cd00110	8.4e-33	1648	1799
Laminin_EGF	pfam00053	9.8e-10	82	129
Laminin_EGF	pfam00053	1.6e-09	132	184
Laminin_EGF	pfam00053	5.4e-15	187	241
Laminin_G_2	pfam02210	6.2e-06	875	1014
Laminin_G_1	pfam00054	6.4e-06	1079	1213
Laminin_G_2	pfam02210	4.2e-26	1079	1210
Laminin_G_1	pfam00054	0.00077	1263	1382
Laminin_G_2	pfam02210	8.8e-20	1263	1379
Laminin_G_1	pfam00054	8.5e-21	1499	1629
Laminin_G_2	pfam02210	1.4e-35	1499	1626
Laminin_G_1	pfam00054	5.6e-15	1676	1804
Laminin_G_2	pfam02210	2e-32	1676	1801
EGF_Lam	smart00180	7.2e-12	82	129
EGF_Lam	smart00180	1.8e-12	132	184
EGF_Lam	smart00180	9.5e-21	187	241
Laminin_I	pfam06008	9e-104	295	555
Laminin_II	pfam06009	9.4e-53	734	861
LamG	smart00282	3.4e-33	857	1014
LamG	smart00282	4.4e-32	1071	1210
LamG	smart00282	7.2e-12	1255	1379
LamG	smart00282	1e-40	1491	1626
LamG	smart00282	7.8e-34	1668	1801

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_061348	Polymorphism	p.ALA283GLU	N/A
Swiss-Prot	VAR_056141	Polymorphism	p.ARG154TRP	N/A
Swiss-Prot	VAR_056143	Polymorphism	p.ASN1549SER	N/A
Swiss-Prot	VAR_025551	Polymorphism	p.GLY1117SER	N/A
Swiss-Prot	VAR_056140	Polymorphism	p.GLY94SER	N/A
Swiss-Prot	VAR_056142	Polymorphism	p.LEU492HIS	N/A
Swiss-Prot	VAR_025552	Polymorphism	p.PRO1119ARG	N/A
Swiss-Prot	VAR_069708	Disease	p.PRO950LEU	Cardiomyopathy, dilated 1JJ (CMD1JJ)
Swiss-Prot	VAR_025550	Polymorphism	p.TYR498HIS	N/A
Swiss-Prot	VAR_056144	Polymorphism	p.VAL1815ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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